Open Access DOI:10.23937/2469-567X/1510091
siRNA-Therapy for Hepatitis B Virus (HBV): A Novel Choice for HBV Treatment
Myra Sarfraz Iqbal
Article Type: Review Article | First Published: 2023/11/11
Hepatitis B virus (HBV) is a virus that may lead to chronic infection of the liver. Once infected, HBV may stay in the blood and liver for a lifetime. HBV is a non-retro virus that infects hepatocytes, with an underlying mechanism of converting its relaxed circular DNA (rcDNA), into closed circular DNA (cccDNA). The cccDNA then serves as a transcription template to transcribe viral RNAs utilizing the transcription factors meant for the host system's transcription....
Open Access DOI:10.23937/2469-567X/1510090
Prevalence of Mycobacterium tuberculosis among HIV Patients Attending Federal Medical Centre Asaba, Delta State
Odiase Edgar Onyeka, Olley Mitsan, Daniel Ohilebo Ugbomoiko, Theophilus Ogie Erameh, Ezekiel Dauda Gambo, Ofili Sandra Kanwulia, Muhammad Adamu Ibrahim and Paul Yiran Ntasin
Article Type: Original Research | First Published: 2023/10/09
Co-infection with tuberculosis (TB) and human immunodeficiency virus (HIV) is a major public health issue worldwide. Despite greater access to antiretroviral medication (ART), mortality in PLHIV remains high, with tuberculosis (TB) being the major cause of death. The rising prevalence of HIV/TB co-infection is concerning. Understanding the incidence of tuberculosis among HIV seropositive people...
Open Access DOI:10.23937/2469-567X/1510089
AI in the Management of HIV: Case Study Cameroon
ANGYIBA Serge Andigema, NGNOTOUOM NGNOKAM Tania Cyrielle, KOUDOM Patrice Landry and ABENA Jerry Vladimir
Article Type: Research Article | First Published: 2023/07/19
With the spread of HIV, the world is currently confronting an unprecedented problem. The application of artificial intelligence (AI) to the management of HIV is a hotly debated subject. Over 6,000 people are newly diagnosed with HIV each year in the United States, where an estimated 1.2 million people have the disease (CDC, 2020). HIV-positive individuals need ongoing medical care as their condition worsens in order to track the virus' development and ensure that the right therapy is being given...
Open Access DOI:10.23937/2469-567X/1510088
Cardiovascular Involvement in People Living with Human Immunodeficiency Virus on Highly Active Antiretroviral Therapy
H.K. Aggarwal, Deepak Jain, P Harish, Shaveta Dahiya, Sandeep Kaur and Ashwani Kumar
Article Type: Research Article | First Published: 2023/06/21
The present study was a cross-sectional, observational study carried out in a tertiary care centre from January 2021 to July 2022. 200 HIV positive individuals on HAART for atleast 2 years were included who underwent ECG, chest radiograph, 2D Echocardiography and CD4+ T cell count along with other routine investigations. Presence of cardiovascular involvement was determined on the basis of echocardiographic abnormalities and these findings were associated with demographic, haematological and bio...
Open Access DOI:10.23937/2469-567X/1510087
Aids and Non-Hodgkin Lymphoma: Report of a Case
López de la Cruz Denisse, Azucena Casanova Lara and María Valeria Jiménez Báez
Article Type: Case Report | First Published: 2023/06/15
AIDS (Acquired Immunodeficiency Syndrome) is a condition caused by the Human Immunodeficiency Virus (HIV). HIV is a virus that attacks the immune system and weakens the body's ability to fight off infections and diseases. Approximately 37.6 million people (about twice the population of New York) worldwide are infected with the human immunodeficiency virus (HIV) according to data from the Joint United Nations Program on HIV-AIDS....
Open Access DOI:10.23937/2469-567X/1510085
Current Update of Severe Acute Respiratory Syndrome Coronavirus 2
Behre Dari Mosa, Yasin Awol Wabe and Neja Awol Mohammed
Article Type: Case Report | First Published: 2023/04/19
Coronaviruses are group viruses belong to Corona viridae family the order Nidovirales, and the genus Coronavirus. They are the largest group of viruses causing respiratory infections. There are four genera under this family; Alpha coronavirus, Beta coronavirus, Gamma coronavirus, and Delta coronavirus....
Open Access DOI:10.23937/2469-567X/1510084
Thrombotic Microangiopathies as Initial Presentation of HIV: Two Case Reports and Literature Review
Rawan AlAgha
Article Type: Case Report | First Published: March 09, 2023
Thrombotic microangiopathies have been recently a recognizable presentation of patients infected with Human Immunodeficiency Virus (HIV). Most of those who present similarly noted to have poor prognosis as majority have advanced HIV with low CD4 counts. It has postulated by some authors and researches that it should be recognized as an AIDS defining condition. Here we present two cases of adult males who presented with features of thrombotic microangiopathy and were diagnosed to have HIV for the...
