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Otolaryngology and RhinologyISSN: 2572-4193

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 Open Access DOI:10.23937/2572-4193.1510031

Synchronous Clival Chordoma and Sellar-Suprasellar Germinoma in a Pediatric Patient: Case Report and Review of Literature

Vidur Bhalla, Thomas Muelleman, Chelsea S Hamill, D David Beahm, Hesham M Soliman, Roukoz B Chamoun and Kathy Newell

Article Type: Case Report | First Published: May 31, 2017

Pediatric brain tumors are the leading cause of cancer in children. While children more likely present with craniopharyngiomas, germinomas or optic gliomas, synchronous intracranial lesions are highly uncommon. Here, we describe the case of a 10-year-old female who presented with central Diabetes Insipidus (DI)....

 Open Access DOI:10.23937/2572-4193.1510030

Synchronous Laryngeal Tuberculosis and Cancer, a First in Literature

Thilaga Rajendran, Velayutham Kamaru Ambu and Azila Alias

Article Type: Case Report | First Published: March 30, 2017

Laryngeal cancer is rising in incidence among elderly men with history of smoking. Laryngeal tuberculosis is a rare clinical entity and the incidence is significantly less than 1% of all tuberculosis. This case report highlights the co-existence of laryngeal cancer and TB in a 75-year-old man who presented to us with a 4-year history of hoarseness....

 Open Access DOI:10.23937/2572-4193.1510029

In Vitro Modulation of MMP-2 and MMP-9 Secretion by Cytokines, Inducers, and Inhibitors in Head and Neck Squamous Carcinoma Cells (FaDu) and Tongue Carcinoma Cells (SCC-25)

M Waheed Roomi, Bilwa Bhanap, Aleksandra Niedzwiecki and Matthias Rath

Article Type: Research Article | First Published: February 21, 2017

Head and neck squamous cell carcinoma (HNSCC) is a devastating disease with poor prognosis. Matrix metalloproteinases (MMPs), specifically, MMP-2 and MML-9 play a critical role in tumorigenesis by their ability to modify tumor microenvironments, facilitating cell invasion and metastasis. We compared MMP secretion by various cytokines, inducers, mitogen, inhibitors that regulate MMP-2 and MMP-9 activities in FaDu and Tongue cancer cell lines....

 Open Access DOI:10.23937/2572-4193.1510028

Inadvertent Vocal Fold Polypectomy During Tracheal Intubation; A Case Report

Sean Keane, Patrick Dillon and John E Fenton

Article Type: Case Report | First Published: January 21, 2017

A 48-year-old male presented for microlaryngoscopy and vocal fold polypectomy, which was complicated by polyp displacement into the lower respiratory airway during direct laryngoscopy and tracheal intubation. It is the first reported incidence of such a case. Following preoperative assessment and preparation, anaesthesia was induced and the airway secured using direct laryngoscopy and tracheal intubation with a microlaryngoscopy tube (MLT), which was reported uneventful....

Volume 3
Issue 1