The main feature of modern injection methods of dental anesthesia is in the local venous spreading of the anesthetic in the near-toothed spongy substance of the bone and dental pulp. The vascular mechanism is controlled by the epinephrine anesthetic solution and patient vegetal system. Spongy dental anesthesia is universal, highly effective, relatively safe, easy to implement and increasingly widespread. Classification proposed by us is the division of injection methods of anesthesia into traditional diffuse: Infiltrative and conductive, and diffuse-vascular: Intraosseous, intraligamentary, intraseptal and intrapulparial.