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Citation

Çakıcı EK, Şükür EDK, YazılıtaŞ F, Gür G, Güngör T, et al. (2019) White Coat Hypertension in Children and Adolescents: Innocent or Not?. J Hypertens Manag 5:043. doi.org/10.23937/2474-3690/1510043

Copyright

© 2019 Çakıcı EK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

RESEARCH ARTICLE | OPEN ACCESS DOI: 10.23937/2474-3690/1510043

White Coat Hypertension in Children and Adolescents: Innocent or Not?

Evrim Kargın Çakıcı*, Eda Didem Kurt Şükür, Fatma YazılıtaŞ, GökÇe Gür, Tülin Güngör, Evra Çelikkaya, Deniz Karakaya and Mehmet Bülbül

Department of Pediatric Nephrology and Rheumatology, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey

Abstract

Background

The clinical significance of white coat hypertension is still uncertain. We aimed to evaluate children with white coat hypertension regarding their clinical, laboratory characteristics, evidence of target organ damage and compare them to normotensive and hypertensive children.

Methods

Fourty patients diagnosed with white coat hypertension, 40 patients with primary hypertension and 40 normotensive children of similar age, gender and body mass index were included in the study. Ambulatory blood pressure monitoring and echocardiographic examination were performed to all children. Clinical and laboratory characteristics were noted.

Results

All ambulatory blood pressure monitoring parameters, except night-time diastolic blood pressures and loads, were significantly higher in patients with white coat hypertension compared to normotensive ones. Left ventricular hypertrophy was 35% in the primary, 15% in the white coat hypertension group, and no left ventricular hypertrophy was detected in normotensive patients. No significant difference was found between 3 groups in terms of proteinuria or retinopathy.

Conclusion

Children diagnosed with white coat hypertension had ambulatory blood pressure monitoring measurements and left ventricular mass index values smaller than patients with primary hypertension but more than normotensive children. Echocardiographic changes might suggest that white coat hypertension can be associated with target-organ damage.