Open Access DOI:10.23937/2378-3656/1410105

The Spread of Melanoma to the Adrenal Glands: Historical Cases

Wilson I B Onuigbo

Article Type: Review Article | Publication Updated: May 12, 2016

Personal interest in cancer metastasis to the adrenal glands began in 1957 and matured in a Doctorate Thesis in 1961. Part of its eminence lay in cases in which it was the only soil selected for attack. What of the melanoma? The available historical account did not contain this answer. Therefore, this paper aims to determine the situation in the classical Transactions of the Pathological Society of London, which began to publish during the 1846 - 1848 period....

 Open Access DOI:10.23937/2378-3656/1410104

Neurobiology of KB220Z-Glutaminergic-Dopaminergic Optimization Complex [GDOC] as a Liquid Nano: Clinical Activation of Brain in a Highly Functional Clinician Improving Focus, Motivation and Overall Sensory Input Following Chronic Intake

Lucien L Duquette, Frank Mattiace, Kenneth Blum, Roger L Waite, Teresa Boland,Thomas McLaughlin1, Kristina Dushaj, Marcelo Febo and Rajendra D Badgaiyan

Article Type: Case Report | Publication Updated: May 11, 2016

With neurogenetic and epigenetic tools utilized in research and neuroimaging, we are unraveling the mysteries of brain function, especially as it relates to Reward Deficiency Syndrome (RDS). We encourage the development of pharmaceuticals or nutraceuticals that promote a reduction in dopamine resistance and balance brain neurochemistry, leading to dopamine homeostasis. We disclose self-assessment of a highly functional professional under work-related stress following KB220Z use, a liquid (aqua) ...

 Open Access DOI:10.23937/2378-3656/1410103

Giant Mucinous Cystadenoma of the Ovary Mimicking Ascites: A Case Report

Marco Rossato, Marta Burei and Roberto Vettor

Article Type: Case Report | Publication Updated: April 30, 2016

In the present case report we describe a 67 years old woman with clinically apparent ascites and no systemic causes for it and a giant mucinous cystadenoma of the right ovary diagnosed utilizing the CT scan and confirmed by the histological findings. Ascites consists in the accumulation of fluid within the peritoneal cavity and is a common finding with a wide range of causes. Although at least 80% of patients with ascites are found to have liver cirrhosis other pathologies as well as heart failu...

 Open Access DOI:10.23937/2469-5718/1510042

Effect of Flare Reaction to Intra-Articular Hyaluronan Injection on Cartilage Boundary Lubricating Ability of Human Synovial Fluid

Taryn E Ludwig, Jenelle R McAllister, Victor Lun, J Preston Wiley and Tannin A Schmidt

Article Type: Original Article | Publication Updated: July 01, 2016

Lubrication of articular cartilage is achieved by a combination of lubrication mechanisms. Fluid film lubrication occurs at high speeds and low loads when cartilage surfaces are separated by a layer of synovial fluid (SF). Boundary lubrication occurs at low speeds and high loads when cartilage surfaces are in contact and lubrication is provided through molecular interactions at the surface....

 Open Access DOI:10.23937/2469-5718/1510041

The Suitability of Global Rating Scales to Monitor Arthroscopic Training Progress

JJ Stunt, GMMJ Kerkhoffs, B van Ooij, IN Sierevelt, MU Schafroth, CN van Dijk, J Dragoo and GJM Tuijthof

Article Type: Original Article | Publication Updated: May 17, 2016

As developing arthroscopic skills is challenging and training time for residents is limited, arthroscopic skill competency of residents should be measured. Assessment tools, such as Global Rating Scales (GRS), have been developed for structured, objective feedback and to assess learning curves. The goal of this study is to assess known-groups and convergent validity of these scales, to evaluate the suitability of these scales to monitor training progress of residents....

 Open Access DOI:10.23937/2469-5718/1510040

Evaluation of Physical Activity Intensities and Energy Expenditure in Overweight and Obese Adults

Ludivine Paris, Martine Duclos, Romain Guidoux, Nicolas Lamaudiere and Sylvie Rousset

Article Type: Original Article | Publication Updated: April 04, 2016

Western lifestyle characterized by lack of physical activity and diet rich in fat and refined sugars is associated with various non-communicable chronic health diseases. The prevalence of obesity worldwide is steadily increasing. In 2014, 39% of adults worldwide were overweight and 13% were obese. Physical inactivity, sedentary behaviors and an excessively rich diet are responsible for chronic imbalance between energy intake and expenditure favoring the development of obesity and its co-morbid...

 Open Access DOI:10.23937/2469-5769/1510020

Over-The-Counter Products and Food Allergy in Children

Luis Miguel Borrego, Magna Correia, Ines Mota and Mario Morais-Almeida

Article Type: Case Report | Publication Updated: June 07, 2016

Over-the-counter medicines are available without prescription, allowing for convenience and facilitating self-care. We report a case of an adverse reaction to a pharmaceutical formula for gingival eruption in a child with milk allergy. The objective of this report is to alert health-care professionals regarding the potential threat of over-the-counter formulations to children with food allergy. Over-the-counter (OTC) medicines are available without prescription. As the number of OTC drugs rise, ...

 Open Access DOI:10.23937/2469-5769/1510019

Linear Growth Predicts Acute Post-Transplant Outcomes in Paediatric Liver Transplant Patients

Jillian S Owens, Michele Strom, Farsad Farassati, Krista Van Roestel, Kathryn Chambers, Penni Kean, Megan Carricato, Vicky L Ng, Yaron Avitzur and Glenda Courtney Martin

Article Type: Research Article | Publication Updated: May 24, 2016

Minimal research has been conducted on the effect of nutritional status on acute post-transplant outcomes in pediatric liver transplant patients. The purpose of this study was to determine the effect of pre-transplant nutritional status (height, weight, albumin, hemoglobin, Vitamin A, Vitamin E, Vitamin D, mean corpuscular volume (MCV), calcium, magnesium and phosphorus) on acute post-transplant outcomes (length of hospital stay and infection rate)....

 Open Access DOI:10.23937/2469-5769/1510018

Initial Mental Health Evaluation of Internationally Adopted Youth: Goals and Timing Considerations

Rowena Ng, Jennifer Tang and Maria Kroupina

Article Type: Short Communication | Publication Updated: May 16, 2016

Internationally adopted (IA) children are at a greater risk for emotional, behavioral and adaptation difficulties, relative to typically-developing youth due to the fact that many of them experience severe social-emotional deprivation and other adverse experiences preadoption. Importantly, a disproportionate number of IA children show insecure attachment with caregivers even post-adoption, which has been associated with later problems with affect and behavioral regulation. Notably, research has ...

 Open Access DOI:10.23937/2474-3658/1510013

Tuberculosis Control in Jiangsu Province, China

Li Yan, Zhu Limei, Cheng Chen, Lu Wei, Booker G.W, Yu Hao and Polyak S.W

Article Type: Review Article | Publication Updated: May 02, 2016

Tuberculosis (TB) has been a major health problem for thousands of years. It took almost 200 years after the discovery of the disease in early 1689 to identify the causative pathogen, namely Mycobacterium tuberculosis by Robert Koch who was awarded a Nobel Prize in physiology or medicine in 1905 for his work in this area. Currently, TB is a global pandemic that outranks HIV-AIDS and malaria as the leading cause of death by infectious disease. In 1993 the World Health Organization declared TB a g...