Advanced bioinformatics methods were used to gain a thorough understanding of the genetic landscape of colorectal cancer. The transcriptome RNA-seq raw data were obtained from PRJEB24758 in the European Nucleotide Archive (ENA) database. Then, the Sequence Read Archive (SRA) runs a selection to download the sequences database. The transcriptomic RNA released data is analyzed by the bioinformatics tool, which also uses online analytic tools to help visualize the results and identify key genes tha...

Many hematologic malignancies, including leukemia (AML/CML), myelodysplastic syndrome (MDS), and aplastic anemia, predominantly affect older adults. Allogeneic hematopoietic stem cell transplantation (AHSCT) offers a potential cure for intermediate- to high-risk disease. However, it is infrequently offered to patients older than 70 due to concerns about tolerability. AHSCT in elderly patients remains a challenge. Further studies are needed to refine patient selection criteria, identify key demog...