Open Access DOI:10.23937/2643-4474/1710133
Wrong Use of Oxygenated Water to Preparation the Skin before Surgery
Ali Riazi, Ata Mahdkhah, Navid Askariardehjani and Zhale Kazemi
Article Type: Case Report | First Published: February 27, 2023
Oxygenated water or hydrogen peroxide is a chemical compound with the formula H2 O2 . Oxygenated water is a common oxidant made from a combination of oxygen and hydrogen. Oxygenated water decomposes slowly in the absence of catalysts. This unstable compound decomposes under heat and decomposes into water and oxygen over time. This commercial material is sensitive to light and decomposes rapidly in the presence of light and is therefore stored in dark containers. This compound has antibacterial, ...
Open Access DOI:10.23937/2643-4474/1710132
Dwyer Instrumentation for Scoliosis, a Challenge for Neuraxial Anesthesia: A Case Report
Sai Pentyala, MD, Mickael Marc Antoine A Khouzami, MD, Barbara Orlando, MD, PhD, Nwadiogo Ejiogu, MD, MA and Deborah Stein, MD
Article Type: Case Report | First Published: December 19, 2022
We describe the case of a patient with severe scoliosis, following Dwyer instrumentation and Harrington rods insertion during adolescence, presenting for labor analgesia. Ultrasonography in accordance with radiographic imaging was used to guide the placement of an epidural catheter, successfully used for pain control during labor in an otherwise challenging patient....
Open Access DOI:10.23937/2643-4474/1710131
Concurrent Pituitary Adenoma and Intraventricular Glioblastoma Multiforme: A Case Report and Review of the Literature
Chattrabongkot Chokaouychai, MD and Raywat Noiphithak, MD
Article Type: Case Report | First Published: December 14, 2022
Intracranial tumors of different histologic morphologies in concurrent existence are extremely rare with an incidence rate less than 0.9% among the cases of primary brain tumors. Here, we report a case of a 57-year-old male who was diagnosed with coexistence of nonfunctioning pituitary adenoma (PA) and intraventricular glioblastoma multiforme (GBM). She presented with blurred vision from pituitary tumor and right-sided weakness from intraventricular tumor. Interhemispheric transcallosal approach...
Open Access DOI:10.23937/2643-4474/1710130
Intraoperative Pulseless Electrical Activity Cardiac Arrest during Intracranial Aneurysm Clipping: Case Report
Alaa Al-Mohammad, PhD, Soghakhawari, MRCS, Will Muirhead, FRCS, Lila Dinner, FRCA and Mary Murphy, FRCS
Article Type: Case Report | First Published: November 25, 2022
Cardiac arrest is a rare intraoperative complication with few cases reported during neurosurgery. Proposed causes of PEA cardiac arrest in this setting include medications, irrigation, coronary vasospasm, and elicitation of the trigeminocardiac reflex. Here, we report the case of a 52-year- old man who suffered an intra-operative pulseless electrical activity (PEA) cardiac-arrest while undergoing elective clipping of a right MCA bifurcation aneurysm through pterional craniotomy....
Open Access DOI:10.23937/2643-4474/1710129
Anatomical Classification of Arterial Compression in Neurovascular Syndromes: Microsurgical Perspective
KUZUCU Pelin, MD, TÜRKMEN Tolga, MD, KARA Enes, MD, GÖKALP Elif, MD, YAMAN Mesut Emre and AYKOL Şükrü, MD
Article Type: Original Article | First Published: November 19, 2022
Trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia are defined as neurovascular syndromes and are conditions of compression of the cranial nerves by vascular structures. The aim of this study is to make the surgical approach safer by providing aggregate data on vascular structures and their aspects that cause compression in neurovascular syndromes....
Open Access DOI:10.23937/2643-4474/1710126
FAHR's Disease and MCA Aneurysm Bleeding Case Report
Aykut İLİKHAN, Şükrü ORAL, Mehmet Berat ERTURHAN and Masud YUSİFOV
Article Type: Case Report | First Published: November 09, 2022
Fahr's disease is named after the German neurologist Karl Theodor Fahr, who first reported it in 1930. This is a rare neurological condition characterized by abnormal idiopathic calcification of the basal ganglia and is usually inherited in autosomal dominant manner. These calcifications are consisted of calcium carbonate and phosphate, and may also occur in some other locations, such as thalamus, hippocampus, dentate nucleus, cerebral cortex, and cerebellar subcortical white matter....
Open Access DOI:10.23937/2643-4474/1710124
Primary Glioblastoma of Trigeminal Root Entry Zone and Internal Auditory Canal: Case Report
Jalil Habert, ThiNgocPhuong Nguyen, MD, Emmanuel Hologne, MD, Anne Doe de Maindreville, MD, Sofiene Cheikh-Rouhou, MD and Laurent Pierot, MD, PhD
Article Type: Case Report | First Published: October 17, 2022
Glioblastoma developed from cranial nerves are extremely rare. We report the case of a 71-year-old woman with glioblastoma arising from both trigeminal root entry zones and Internal Auditory Canal (IAC) nerves. The patient presented with facial numbness and paresthesia in both trigeminal sensory territories with initial Magnetic Resonance Imaging (MRI) at 1-month follow up showing contrast enhancement and thickening of both trigeminal nerves root entry zone and moderate thickening of IAC bundle,...
Open Access DOI:10.23937/2643-4474/1710123
Case Report: Use of MLC601 in Severe Traumatic Brain Injury
Ramesh Kumar, Peh Hong Shawn and Narayanaswamy Venketasubramanian
Article Type: Case Report | First Published: October 14, 2022
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. The medical management of TBI involves stabilization of the individual and focusing on preventing further injury. There are no proven pharmacological therapies to enhance recovery after severe TBI....
Open Access DOI:10.23937/2643-4474/1710122
The Association of Adem with Hydrocephalus and COVID-19
Ali Riazi, Atta Mahdkhah and Navid Askariardehjani
Article Type: Case Report | First Published: September 30, 2022
Adem is an autoimmune disease that can happen after any kind of inflammation and infection. This disease is highly progressive and occurs in the central nervous system. This disease commonly affects children. And in general, it is part of very uncommon diseases. This disease affects more males than females. In most cases, ADEM is associated with or caused by a viral disease or bacteria....
Open Access DOI:10.23937/2643-4474/1710121
Sigma Perforation and Septic Peritonitis after an Anterior Lumbar: A Case Report and Literature Review
Ricou E, MD, Fa-Binefa, MD, Maldonado V, MD, Torrents R, MD and Moya I, MD2
Article Type: Case Report | First Published: September 30, 2022
Anterior lumbar interbody fusion (ALIF) has become widely accepted for the treatment of discogenic low back pain, achieving similar radiological and clinical treatments to other techniques. To describe sigma perforation and septic peritonitis as a potentially fatal complication after an anterior interbody fusion....
Open Access DOI:10.23937/2643-4474/1710120
Adult Pilocytic Astrocytoma: A Report of Two Cases and Literature Review
Daisuke Wajima, MD, PhD, Takaaki Nagashima, MD, Toshiaki Goda, MD, Rin Shimozato, MD, Tomonori Tekeshita, MD, PhD and Tomoaki Nagamine, MD
Article Type: Case Report | First Published: September 28, 2022
Pilocytic astrocytoma (PA) is classified as a benign tumor, which is rarely reported in adults. We present two case reports of adult PAs (APAs) and a literature review. In Case 1, a 25-year-old man presented with progressive right parieto-temporal head puffing. Head computed tomography (CT) revealed multiple large cystic tumors with a midline shift....
Open Access DOI:10.23937/2643-4474/1710119
Hirayama Disease: A Case Report and Review of Literature
Dr. Anurag Chandrakant Dandekar and Dr. Nirav A Mehta
Article Type: Case Report | First Published: September 15, 2022

Hirayama disease is a rare disorder seen in young patients in their second or third decade of life with slowly progressive self-limiting distal upper limb muscle weakness with seldom symmetrical involvement. It is a peculiar anterior horn cell disease that is managed conservatively with limited surgical options available as per literature....
Open Access DOI:10.23937/2643-4474/1710118
Role of Perioperative Plasma D-dimer in Intracerebral Hemorrhage after Brain Tumor Surgery: A Prospective Study
Estela Val Jordán, Agustín Nebra Puertas, Juan Casado Pellejero, Concepción Revilla López, Nuria Fernández Monsteirín, Lluis Servia Goixart and Manuel Quintana Díaz
Article Type: Prospective Observational | First Published: July 30, 2022
Intracerebral hemorrhage (ICH) is one of the most feared complications after brain tumor surgery. Despite several factors are considered to influence bleeding, an increasing number of clinical studies emphasize that hemostatic disorders, developed during surgical aggression and tumoral status, could explain unexpected ICH....
Open Access DOI:10.23937/2643-4474/1710117
Intraparenchymal Hemorrhage in En coup de sabre: A Case Report
Benjamin Ramsey, BS, Chelsea Reynolds, DO and Catherine McClung Smith, MD
Article Type: Case Report | First Published: July 30, 2022
Linear scleroderma, otherwise known as encoup de sabre (ECDS), is a form of scleroderma that affects the face and scalp and typically presents with unilateral streaks of induration with pigment changes of the skin which can involve the underlying dermis, soft tissue, and bone. In cases where there is progression to unilateral facial atrophy, this is known as parry-romberg syndrome (PRS)....
Open Access DOI:10.23937/2643-4474/1710116
Early Distal Coil Migration Requiring Surgical Treatment
Mickaela Echavarria Demichelis, MD, Derek O Pipolo, MD, Alvaro Campero, MD, PhD,Juan F Villalonga, MD, Nicolas Kusznir, MD and Matias Baldoncini, MD
Article Type: Case Report | First Published: July 21, 2022
Coil migration is a rare but devastating endovascular complication that can lead to severe neurological deficit. There are only 11 cases reported in the literature, with the majority located within the middle and anterior cerebral arteries. The objective of this article is to describe our experience in the management of an unusual case of a cerebral aneurysm with distal coil migration....
Open Access DOI:10.23937/2643-4474/1710114
Prolactin-Secreting Clival Ectopic Pituitary Adenoma
Lydia A Leavitt
Article Type: Case Report | First Published: June 03, 2022
A 69-year-old female with a 30-year history of hyperprolactinemia symptomatically controlled with dopamine agonist therapy presented with complaints of worsening headaches. Findings on physical examination and endocrine studies were unremarkable....
Open Access DOI:10.23937/2643-4474/1710113
Quadrigeminal Miracle: Regaining Hearing
Maidan Aiman, MD, Moldabekov Aidos, MD, Zhetpisbaev Berik, MD, Ryskeldiyev Nurzhan, Ashirov Nurali, MD, Teltayev Daniyar, MD and Akshulakov Serik
Article Type: Case Report | First Published: June 03, 2022
Pineal region tumors are classically presented with vertical gaze palsy, hypothalamic symptoms, or, more often, hydrocephalus, by obstructing the aqueduct. This case report describes a patient with obstructive hydrocephalus and a hearing loss as an initial complaint of pineal region tumor....
Open Access DOI:10.23937/2643-4474/1710112
Frontosphenoidal Craniosynostosis: An Uncommon Cause of Anterior Plagiocephaly
Victoria Becerra, MD, PhD, Jose Hinojosa, MD, PhD, Santiago Candela, MD, PhD, Diego Culebras, MD and Mariana Alamar, MD
Article Type: Case Report | First Published: June 03, 2022
We report three patients diagnosed with anterior plagiocephaly caused by frontosphenoidal synostosis and compare it with the clinical features and surgical implications of a patient affected by unilateral coronal craniosynostosis....
Open Access DOI:10.23937/2643-4474/1710110
Intraventricular Metastatic Melanomas: Two Case Reports
Mohamed Alhantoobi, Almunder Algird, Jian-Qiang Lu, John Provias and Kesava Reddy
Article Type: Case Report | First Published: May 20, 2022
A 55-year-old male with a history of left thigh invasive melanoma resected a year ago with negative margins, presented to emergency department with a few days of severe headaches followed by urinary incontinence and decreased level of consciousness....
Open Access DOI:10.23937/2643-4474/1710111
Cerebral Salt Wasting after Pituitary Surgery for Acromegaly: A Case Report
Christian Schill, BS, Sabrina Meftali, MD, Hugh Moulding, MD, PhD and Bankim Bhatt, MD
Article Type: Case Report | First Published: May 21, 2022
Cerebral salt wasting, a rare complication of cranial neurosurgery, has not been reported after a functional pituitary tumor resection. The simultaneous presentation of diabetes insipidus (DI) and cerebral salt wasting after pituitary surgery presents a unique diagnostic challenge. We present a case of a 27 y.o. man with a 6-month history of acromegaly as evident by an IGF-1 of 1040 ng/ mL (reference range: 101-307 ng/mL). MRI of the pituitary revealed a 3.2 cm × 3.2 cm × 3.1 cm macroadenoma e...
Open Access DOI:10.23937/2643-4474/1710109
Cervical Myelopathy Mimicking Intramedullary Tumor: A Case Report and Review of Literature
Atul Vats, Shahid Khan and Farooq Aziz
Article Type: Case Report | First Published: May 20, 2022
Cervical spondylotic myelopathy can mimic an intramedullary tumor. We report a case of a young male who presented with gradually progressive myelopathy. MRI cervical spine with contrast revealed a contrast enhancing lesion. Anterior cervical discectomy with fusion was done. In case of a progressive cervical myelopathy with atypical radiographic appearance initial decompression and follow-up with an MRI might be the procedure of choice, if a clear diagnosis for a causative treatment cannot be mad...
Open Access DOI:10.23937/2643-4474/1710108
Meningosarcoma in The Infratemporal Fossa: An Unusual Presentation
Guido GABRIELE, Flavia CASCINO, Linda LATINI and Biagio Roberto CARANGELO
Article Type: Case Report | First Published: April 30, 2022
Meningosarcoma represent a rare disease with an uncertain prognosis. Moreover, localization of tumours in the infratemporal fossa is rare. Lack of associated symptomatology of infratemporal fossa’s lesions could result in a diagnosis and treatment delay. Also, surgical management of infratemporal fossa neoplasm remain challenging. The authors present the case of a meningosarcoma extended to the infratemporal fossa, which presented in an advanced stage and required other treatment further than ...
Open Access DOI:10.23937/2643-4474/1710107
Intracranial Injection of Fibrinolytic Agent in a Patient with Iatrogenic Artery Thrombosis following Clipping of the Middle Cerebral Artery Aneurysm
Pilipenko Yuri, MD, PhD, Konovalov Anton, MD, PhD, Poluektov Yuri and Eliava Shalva, MD, PhD
Article Type: Case Report | First Published: April 25, 2022
Patient F, male, 43-years-old, presented with a subarachnoid hemorrhage. CT angiography revealed an 8 mm saccular aneurysm in the trifurcation of the left middle cerebral artery (MCA) (Figure 1). When the patient’s condition stabilized, he was transferred to our center for surgical treatment 30 days after the hemorrhage. The patient’s condition was satisfactory at admission. No cerebral neurological symptoms were detected. The patient underwent microsurgical clipping of the aneurysm neck in ...
Open Access DOI:10.23937/2643-4474/1710106
A Case of Transdural and Metastatic Intracranial Meningeal Spread following Resection of a Temporal Frontal Lobe Gliosarcoma
Loukas Georgiou, BS, Mark Burton, MD, Brian Walker, DO and Anastasios Georgiou, MD
Article Type: Case Report | First Published: April 20, 2022
Gliosarcoma is a very uncommon primary brain malignancy and is considered a subtype of glioblastoma. It represents approximately 2% of cases classified as glioblastoma. Treatment of gliosarcoma follows the paradigm for glioblastoma with recommendations for a maximal allowable resection followed by post-operative radiation therapy to the operative bed with concurrent temozolomide. Although still being a rare occurrence, gliosarcomas have a relatively higher propensity for transdural growth either...
Open Access DOI:10.23937/2643-4474/1710105
Usage of Denosumab for Giant Cell Rich Tumors: A Case Study and Literature Review
Shivum Desai, BS, Jingya Miao, MS, Alice S Wang, BS and Omid Hariri, DO, MSc
Article Type: Case Study and Literature Review | First Published: April 20, 2022
Denosumab is a human monoclonal antibody to receptor activator of NF-κB ligand (RANKL), which has been FDAapproved for the management of giant cell tumor of bone. Here, we present a case of 21-year-old female with solid aneurysmal bone cyst (ABC) treated with denosumab for 6 months to date. The patient experienced positive outcomes as the result of denosumab therapy. Although the use of denosumab has been reported in a number of studies, its off-label use for treatment of ABC and other giant ce...
Open Access DOI:10.23937/2643-4474/1710104
A Rare Cause of Increased Intracranial Pressure and Papilloedema: An Intradiploic Epidermoid Cyst
George Bonanos, Shahid Kahn, Peter Kralt and Nitin Mukerji
Article Type: Case Report | First Published: April 15, 2022
We present a rare cause of increased Intracranial Pressure (ICP) and papilloedema in a male adult. The presenting symptoms of blurred vision and headaches were investigated with brain imaging which revealed an intradiploic epidermoid cyst, extending intracranially compressing the torcular Herophilli. Presence of papilloedema should trigger cranial imaging to look for causes of raised intracranial pressure. Obstruction of the venous sinuses flow is a recognized cause of raised intracranial pressu...
Open Access DOI:10.23937/2643-4474/1710103
Prenatally Diagnosed Suprasellar Arachnoid Cyst: When to Treat?
Baticam NS, Alloy E, Rolland A, Fuchs F and Roujeau T
Article Type: Case Report | First Published: April 08, 2022
Suprasellar Arachnoid Cysts (SAC) are rare heterogenous entities that can be diagnosed and treated prenatally or postnatally, depending on their type and symptoms. We report a case of a prenatally diagnosed suprasellar arachnoid cyst treated postnatally. The cyst was diagnosed on a routine ultrasound at 22 weeks of gestation. It was a very large cyst in the prepontine region, compressing the brain stem and the 4th ventricle, causing a ventriculomegaly. The cyst was rapidly evolutive in the ultra...