Open Access DOI:10.23937/2377-3634/1410040
Risk of Falls in People with Diabetes Mellitus
Alessandra Madia Mantovani, Mariana de Carvalho Pinto, Roselene Mondolo Regueiro Lorenconi, Mariana Romanholi Palma, Fernanda Elisa Ribeiro and Cristina Elena Prado Teles Fregonesi
Article Type: Research Article | Indexed Archive: Volume 2
Aim: To identify the risk of falling through a functional mobility test in non-diabetics, individuals with diabetic neuropathy and individuals with diabetic neuropathy and vasculopathy. Methodology: The study was composed of 61 subjects of both genders divided into the control group CG (n=32), diabetic neuropathy group DNG (n=18) and diabetic neuropathy-vasculopathy group (DNVG) (12). The participants underwent initial an evaluation through somatosensory sensitivity tests, diagnosis of polyneuro...
Open Access DOI:10.23937/2377-3634/1410039
Young-Onset Type 2 Diabetes - Time to Realign Clinical Priorities
Soon H Song
Article Type: Commentary | Indexed Archive: Volume 2
Traditionally considered as a disease of the middle-aged, type 2 diabetes (T2D) has become increasingly more prevalent in children, adolescence and young adults below the age of 40. Of concern, this evolution of young-onset T2D is a global phenomenon. Obesity is a major predisposing factor as the age of onset is inversely associated with body mass index, reflecting the consequences of sedentary lifestyle afflicting different nations and cultural backgrounds....
Open Access DOI:10.23937/2377-3634/1410038
Diabetes and Dementia
Mario Barbagallo and Ligia J. Dominguez
Article Type: Commentary | Indexed Archive: Volume 2
Persons with type 2 diabetes mellitus (DM2) have an increased incidence of cognitive decline and dementia. An increased cortical and subcortical atrophy has been found after controlling for vascular disease and inadequate cerebral circulation. A possible role of insulin resistance and hyperinsulinemia has been suggested to mediate the link between DM2 and Alzheimer's Disease (AD). Altered insulin signaling may contribute to AD biochemical and histopathological lesions. Both hyperglycemia and hyp...
Open Access DOI:10.23937/2377-3634/1410036
Toxic AGEs (TAGE) Theory in the Pathogenesis of NAFLD and ALD
Masayoshi Takeuchi, Akiko Sakasai-Sakai, Jun-ichi Takino, Takanobu Takata, Tadashi Ueda and Mikihiro Tsutsumi
Article Type: Mini Review | Indexed Archive: Volume 2
Nonalcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) have become serious health problems worldwide. These two diseases have similar pathological spectra, ranging from simple hepatic steatosis to steatohepatitis, liver cirrhosis, and hepatocellular carcinoma. NAFLD and ALD are frequently accompanied by extrahepatic complications, including cardiovascular disease and malignancy, which influence patient survival. The chronic ingestion of an excessive daily diet (sweetened beve...
Open Access DOI:10.23937/2377-3634/1410035
The Relationship between Diabetes and Retirement from Work: A Ten Year Follow-Up in National Registers
Bryan Cleal and Kjeld Poulsen
Article Type: Research Article | Indexed Archive: Volume 2
Objectives: To investigate the relationship between diabetes, mortality and exit from work using various Danish Pension schemes. Methods: We linked the Danish National Diabetes register with socioeconomic and population-based registers and followed prevalent and incident cases of diabetes for ten years, adjusting for gender, age and socio-occupational group. We analysed the proportion of individuals with diagnosed diabetes before and after entering a normal retirement pen-sion, voluntary early r...
Open Access DOI:10.23937/2377-3634/1410034
Prevalence and Risk Factors of Poorly Controlled Diabetes Mellitus in a Clinical Setting in Guayaquil, Ecuador: A Cross-Sectional Study
Arosemena Coronel M, Sanchez Armijos J, Tettamanti Miranda D, Vasquez Cedeno D, Chang A and Navarro Chavez M
Article Type: Research Article | Indexed Archive: Volume 2
Objective: This study aimed to explore the prevalence of and factors associated with poorly controlled diabetes mellitus (PCDM) in a clinic setting in Ecuador. Methods: A single-center, cross-sectional study conducted in the outpatient endocrinology clinic in Guayaquil, Ecuador registered 209 participants with type 2 diabetes mellitus, tested for glycosylated hemoglobin and interviewed face-to-face using questions from the Instrument to Measure Lifestyle in Diabetics (IMEVID) Questionnaire. Logi...
