Saracoglu A, Tetik S (2018) Hemostatic Coagulation Management in Trauma. Int J Anesthetic Anesthesiol 5:080.


© 2018 Saracoglu A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

REVIEW ARTICLE | OPEN ACCESS DOI: 10.23937/2377-4630/1410080

Hemostatic Coagulation Management in Trauma

Ayten Saracoglu1* and Sermin Tetik2

1Department of Anesthesiology and Reanimation, Marmara University Medical School, Turkey

2Department of Biochemistry, Marmara University School of Pharmacy, Turkey


Trauma is still a leading cause of death in the 21st Century mainly due to uncontrolled hemorrhage. Trauma has also an increasing cost of treatment in patients. Recently we have been aware of the importance of complex hemostatic and immunoinflammatory responses in pathogenesis of "Trauma Induced Coagulopathy". As a result of understanding of changes on coagulation pathway in trauma, different hypotheses put forward explaining the trauma induced coagulopathy. New treatment algorithms also take place in early coagulation management of patients with traumatic coagulopathy. In this review, we aimed to explain pathophysiological determinant of trauma induced coagulopathy and recent evidence-based hemostatic treatment approach for patients with trauma.