Elisa RT, Caterina F, Angela BM, Laura A, Luca P, et al. (2019) Axillary Fox-Fordyce Disease Induced By Laser Hair Removal. J Dermatol Res Ther 5:071.


© 2019 Elisa RT, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

CASE REPORT | OPEN ACCESS DOI: 10.23937/2469-5750/1510071

Axillary Fox-Fordyce Disease Induced By Laser Hair Removal

Robustelli Test Elisa1*, Ferreli Caterina1, Brundu Maria Angela1, Atzori Laura1, Pilloni Luca2 and Rongioletti Franco1

1Section of Dermatology, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

2Section of Pathology, Department of Surgery, University of Cagliari, Cagliari, Italy


Fox-Fordyce disease (FFD) is an uncommon chronic inflammatory skin disease of the apocrine sweat glands that could be considered as a rare adverse event of laser hair removal. It is postulated that laser therapy could induce damage to the follicular infundibulum, resulting in epidermal detachment and altered keratinocytes maturation which led to keratin plugging. Here, we present a case of a post-pubertal woman who developed axillary itchy lesions with clinical and histological features compatible with FFD, after a series of axillary laser hair removal treatments. The management of the condition is unsatisfying: We suggested our patient stopping epilation sessions and applying topical corticosteroids, with good response on symptoms but no significant effect on the lesions.