Review Timeline | CrossMark Policy | ClinMed Features
logo
Journal of

Dermatology Research and TherapyISSN: 2469-5750

Early Online

 Open Access DOI:10.23937/2469-5750/1510132

Dermatologic Lasers: Comprehensive Review of Cosmetic and Therapeutic Uses

Emily H. Miller

Article Type: Literature Review | Indexed Archive: Volume 11

Laser and light therapy for dermatology has revolutionized the practice of dermatology to offer highly accurate, effective therapies for a wide range of skin conditions. This article provides a comprehensive description of dermatologic lasers, covering their history, mechanism of action, classification, application, and relative efficacy....

 Open Access DOI:10.23937/2469-5750/1510131

Use of Verteporfin to Regrow Hair and Reduce Fibrosis after Transplantation

Melissa Toyos, MD, Rolando Toyos, MD, Allison Toyos

Article Type: Review Article | Indexed Archive: Volume 11

Verteporfin is FDA-approved for wet macular degeneration. Recent Stanford research has revealed a novel use for verteporfin promoting scarless skin regeneration by inhibition of Yes-associated protein (YAP), preventing the activation of En1-positive fibroblasts causing scars....

 Open Access DOI:10.23937/2469-5750/1510130

Post-Sternotomy Scarring: Current Challenges and Treatment Strategies for Keloids and Hypertrophic Scars

Wadhah A. Al-Fakih, MD and Shaima A. Al-Bagoush, MBChB

Article Type: Review Article | Indexed Archive: Volume 11

Sternotomy is a common surgical approach in cardiac surgery, but it is associated with the development of both hypertrophic scars (HTS) and keloids. These scars are often problematic, leading to aesthetic concerns, functional impairments, and in some cases, pain or discomfort. This study reviews the various management strategies for keloid and hypertrophic scars post-sternotomy....

 Open Access DOI:10.23937/2469-5750/1510129

What is the Role of Telemedicine and Artificial Intelligence in Pediatric Dermatology?

Sahithi Talasila, BS

Article Type: Review Article | Indexed Archive: Volume 10

Telemedicine has revolutionized pediatric dermatology by offering remote access to specialized care and reducing healthcare costs. The integration of Artificial Intelligence (AI) further enhances diagnostic accuracy and efficiency, transforming patient outcomes. This review examines the current literature on telemedicine and AI in pediatric dermatology, highlighting studies on improved access to care, economic benefits, and diagnostic advancements. Telemedicine has significantly improved access ...

 Open Access DOI:10.23937/2469-5750/1510128

Extramedullary Acute Undifferentiated Leukemia Presenting in the Skin and Lymph Nodes

Jeremy O'Brien, MD, Zern Chantel, MD and Ikpatt Offiong Francis, MD

Article Type: Case Report | Indexed Archive: Volume 10

Extramedullary presentation of acute undifferentiated leukemia is uncommon, and it is unclear if this is an initial manifestation of a subsequent systemic disease. We present a 67-year-old Caucasian female with skin lesions and multiple enlarged lymph nodes. Microscopy showed diffuse leukemic infiltrates, positive for dim CD45, CD34, CD117, TdT, CD56 and CD43, but negative for HLADR, MPO, CD4, CD68, CD3, CD4, CD20, CD19, and CD79a. We discuss the differential diagnosis of acute undifferentiated ...

 Open Access DOI:10.23937/2469-5750/1510127

Case Series of Kaposi Sarcoma in HIV-negative Men who have Sex with Men: Potential Therapeutic Approaches

N.T. Hilhorst, B. Devocht, E. Verhaeghe, L. Lapeire, L. Vandekerckhove, S. Desmet, MA. De Scheerder and L. Brochez

Article Type: Case Series | Indexed Archive: Volume 10

Kaposi sarcoma (KS) is a tumor originating from endothelial cells, both vascular and lymphatic, and is associated with human herpesvirus 8 (HHV-8). Four distinct KS subtypes have been defined: Classic, endemic, iatrogenic, and epidemic or acquired immunodeficiency syndrome (AIDS)-related KS. A fifth subtype has more recently been recognized in men who have sex with men (MSM) in the absence HIV infection. We report here on three cases of KS in HIV-negative MSM and review the literature. Two patie...

 Open Access DOI:10.23937/2469-5750/1510126

Sweet Syndrome Induced by AFINITOR: Case Report

Edgar Bedang Mone Keby da Costa, El khalil El Bakali, Papys Mendes, Youssef Zemmez, Rachid Frikh and Naoufal Hjira

Article Type: Case Report | Indexed Archive: Volume 10

This is the most common neutrophilic dermatosis and the prototype of superficial dermal acute neutrophilic dermatoses. Its incidence is rare. Sweet's syndrome predilection is for adults aged 30 to 50, but children have also been reported. There is a female predilection [1]. It is distributed worldwide, with no racial predilection. The typical picture is of a sudden-onset rash, accompanied by high fever and neutrophilic leukocytosis [2]. Recombinant granulocyte-colony stimulating factor (G-CSF) h...

 Open Access DOI:10.23937/2469-5750/1510125

Rapidly Transforming Mycosis Fungoides

Edgar Bedang Mone Keby da Costa, El Khalil El Bakali, Mohamed Amine Ennaciri, Asmae Benzekri, Youssef Zemmez, Rachid Frikh and Naoufal Hjira

Article Type: Case Report | Indexed Archive: Volume 10

Mycosis fungoides and its variants account for almost 50% of all cutaneous lymphomas and around 65% of cutaneous T-cell lymphomas. We report the clinical case of a patient with a tumoral nodule, with progressive evolution and rapid transformation. Our patient was undergoing chemotherapy. After mycosis fungoides, CD30+ cutaneous lymphoproliferations are the most frequent pathologies among cutaneous T-cell lymphomas, accounting for 20% of this group....

 Open Access DOI:10.23937/2469-5750/1510123

Paraneoplastic Pemphigus Pemphigoid Like

Edgar Bedang Mone Keby da Costa, El khalil El Bakali, Hasna Kerrouche, Mohamed Amine Essaudi, Youssef Zemmez, Rachid Frikh and Naoufal Hjira

Article Type: Case Report | Indexed Archive: Volume 10

Paraneoplastic pemphigus is a very rare disease. However, it has been described in many countries. It most often affects middle-aged adults, but a few pediatric cases have also been reported. We report the clinical case of a patient being followed for colon cancer who developed erythematous plaques topped by clear and hemorrhagic bullae. Our patient was undergoing treatment with oral corticosteroids and chemotherapy. Paraneoplastic pemphigus was first described in 1990. Since then, numerous case...

 Open Access DOI:10.23937/2469-5750/1510122

Dermoscopy of Cheilitis: A Comprehensive Review of Principal Findings

Imane KACIMI ALAOUI, Sara ELLOUDI, Sara EL-AMMARI, Zakia DOUHI, Meryem SOUGHI, Hanane BAYBAY and Fatima-Zahra MERNISSI

Article Type: Comprehensive Review | Indexed Archive: Volume 9

Cheilitis, an inflammatory condition affecting the lips, presents with various etiologies and clinical manifestations. Early and accurate diagnosis of cheilitis is essential for appropriate treatment and management. Dermoscopy has emerged as a valuable diagnostic tool in dermatology, allowing for non-invasive visualization of skin structures. This review article aims to provide an in-depth understanding of dermoscopic findings in the context of cheilitis...

 Open Access DOI:10.23937/2469-5750/1510120

Acne Scars: Prevalence and Impact on Quality of Life in Moroccan Patients

Hasna Kerrouch, Youssef Zemmez, Rachid Frikh and Naoufal Hjira

Article Type: Research Article | Indexed Archive: Volume 9

Acne is a common dermatologic condition affecting more than 80% of 11 to 30-year-olds, who often suffer from acne scars. Despite the scarcity of data, acne scarring is thought to negatively impact the quality of life of patients. Therefore, the aim of the present study was to evaluate the prevalence of acne scars and their impact on the quality of life (QOL) in moroccan acne patients....

 Open Access DOI:10.23937/2469-5750/1510119

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis at a Moroccan Referral Hospital

Hasna Kerrouch, Hicham Titou, Rachid Frikh, Mohammed Boui and Naoufal Hjira

Article Type: Research Article | Indexed Archive: Volume 9

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare and severe mucocutaneous reaction mainly due to drugs. Few studies have focused on this medical emergency. This study aims is to describe the epidemiologic, clinical, and treatment outcomes of the patients with SJS/TEN....

 Open Access DOI:10.23937/2469-5750/1510118

Extraneural Soft Tissue Perineurioma: A Case Report

Najoua Ammar, Mariam Meziane, Laila Benzekri, Kawtar Znati and Karima Senouci

Article Type: Case Report | Indexed Archive: Volume 8

A perineurioma is a rare benign peripheral nerve sheath tumor derived from perineurial cells. Based on clinical and pathologic features, perineuriomas can be classified into two subtypes: Intraneural perineurioma and the extraneural perineurioma. Soft tissue perineuriomas are rare. Herein, we report a case of Extraneural perineurioma localized in the back....

 Open Access DOI:10.23937/2469-5750/1510117

Characteristics of Physiological Skin Changes in Pregnancy in a Public Maternity in Southern Brazil

Júlia Opolski Nunes da Silva, Rodrigo Ribeiro e Silva, Maria Gabriela Schneider, Maria Carolina Miano Selbach, Maria Eduarda Schramm Guisso, Dieter Alisson Neumann, Luiza Andraus Dantas, Felipe Reinert Avilla Machado, Gabriela Kunz Elias, Marina Quirino Leandro da Silva and Raquel Bissacotti Steglich

Article Type: Research Article | Indexed Archive: Volume 8

To analyze the characteristics of physiological dermatological changes during pregnancy. This is a descriptive study, carried out in a public maternity hospital in southern Brazil, from June to August 2021 through a randomized sample of puerperal women. Through a self-reported interview, maternal-fetal data, sun exposure, photoprotection and skin changes were analyzed. Results: A total of 439 postpartum women were evaluated, 415 (94.5%) of whom presented some dermatological alteration. 237 (54.0...

 Open Access DOI:10.23937/2469-5750/1510116

Short Course Treatment with Dapsone in a 59-Year-Old Male with Dermatitis Herpetiformis: A Case Report

Zacaria B Pario Jr, MD and Victoria P Guillano, MD

Article Type: Review Article | Indexed Archive: Volume 8

Dermatitis Herpetiformis is a chronic autoimmune blistering skin condition that is often associated with gluten-sensitive enteropathy. The primary lesion of DH is an erythematous papule, plaque, or, most commonly, a vesicle that can be pruritic. Most DH patients have an associated GI abnormality and a higher incidence of other autoimmune diseases, such as thyroid disease, insulin- dependent diabetes, lupus erythematosus, and vitiligo. In 70% of cases, patient with DH will require dapsone after...

 Open Access DOI:10.23937/2469-5750/1510115

Evaluation of A Novel Topical Formulation for The Treatment of Problematic Skin: Results of An Italian Clinical Study

Alice Casari, Rima Al Sibai, Michela Mediani, Monica Molinari and Walter Fiore

Article Type: Original Research | Indexed Archive: Volume 8

Problematic skin conditions such as atopic dermatitis, acne vulgaris, and psoriasis are directly linked to microbial imbalance or ‘dysbiosis’. Alterations of skin microbial communities along with other contributing factors, cause skin barrier dysfunction triggering immune and inflammatory responses....

 Open Access DOI:10.23937/2469-5750/1510114

Pseudoxanthoma Elasticum

Youssef Zemmez, Ihssane Hallab, Abir Boulhilat, Adil Elkhoyaali, Jaouad El azhari, Hasna Kerrouch, Rachid Frikh, Mohamed Boui and Naoufal Hjira

Article Type: Case Report | Indexed Archive: Volume 8

Pseudoxanthoma elasticum (PXE) is an inherited disease of elastic tissue primarily affecting the skin, eyes, and arteries. We report a clinical case to emphasize the need for early diagnosis and follow-up, a multidisciplinary approach and the management of complications. A 62-year-old patient consulted for wrinkled layers of papules typically “shagreen”. The skin lesions were disseminated throughout the body but predominated in the folds, abdomen and neck....

 Open Access DOI:10.23937/2469-5750/1510113

Chronic Psoriasis with Vulvar Presentation: A Case Report

Nathan Joshua Manales, BS, Maricela Chavez, MD, MS, Miriam Shayeb, MS and Gary Ventolini, MD

Article Type: Case Report | Indexed Archive: Volume 8

Psoriasis is a fairly common chronic skin condition that presents itself as erythematous, itchy patches with the most commonly affected areas being the elbows, knees, buttocks, scalp, and sites of trauma. Psoriasis of the genitals affects less than half of those diagnosed with psoriasis and can cause major discomfort and frustration. This case report aims to highlight as well as to help discern the presence of vulvar psoriasis among other causes. This report describes a patient with chronic psor...

 Open Access DOI:10.23937/2469-5750/1510112

Reactive Eccrine Syringofibroadenoma: A Case Report

AG Ndoumba Afouba, GA Majoumo Mukam, BS Esson Mapoko, AC Kabeyene Okono, R Bene Belembe and Z Sando

Article Type: Case Report | Indexed Archive: Volume 8

Eccrine syringofibroadenoma is a rare adnexal tumor of sweat glands, with different clinical presentations. It is mainly found at the extremities, but also occurs on the trunk, the nail pulp, or the eyelids. The microscopic examination shows anastomosing cords of cuboidal cells deriving from the epidermis, infiltrating the dermis and separated by a fibrovascular stroma. There are five subtypes among which reactive eccrine syringofibroadenoma, associated with lesions such as chronic ulcer, The ev...

Volume 8
Issue 1