Lahrichi A, Hali F, Baline K, Marnissi F, Chiheb S (2019) Lupus Miliaris Disseminatus Faciei Treated By Isotretinoin and Platelet Rich Plasma. J Dermatol Res Ther 5:072.


© 2019 Lahrichi A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

CASE REPORT | OPEN ACCESS DOI: 10.23937/2469-5750/1510072

Lupus Miliaris Disseminatus Faciei Treated By Isotretinoin and Platelet Rich Plasma

A Lahrichi1,2*, F Hali1,2, K Baline1,2, F Marnissi2,3 and S Chiheb1,2

1Department of Dermatology's Diseases, CHU Ibn Rochd, Casablanca, Morocco

2Faculty of Medicine and Pharmacy, University Hassan II, Casablanca, Morocco

3Anatomopathology Department, CHU Ibn Rochd, Casablanca, Morocco


Lupus miliaris disseminatus faciei (LMDF) is a rare benign dermatosis, of unknown etiology and treatment often disappointing.

An 18-year-old patient presented with lupoid papulonodular lesions in the face. The diagnosis of disseminated lupus of the face was retained after eliminating other diagnoses including sarcoidosis, syphilis and leprosy. An antibacillary treatment was started without improvement for 3 months with onset of lesions. A 0.5 mg/kg/day isotretinoin treatment was started with improvement of the lesions. Thereafter, the patient benefited from 6 sessions of injection of platelet-rich plasma (PRP) with sagging scars.

LMDF is an enigmatic entity, still controversial even though it is widely recognized. Some consider it an entity in its own right whose etiopathogenesis remains to be elucidated.