Localised hypoplasia or aplasia of the great saphenous vein (GSV) is not uncommon, with reports primarily describing limited area of hypoplasia/aplasia around the knee. Long segment of hypoplasia/aplasia extending along the thigh and distally to lower calf is rare. We report a case of an 81-year-old lady with long segment of the GSV aplasia depicted 3 cm distal to sapheno-femoral junction (SFJ), down to 5 cm above the right ankle with direct communication with the short saphenous vein (SSV).