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International Journal of
Radiology and Imaging Technology ISSN: 2572-3235

Citation

Antje Fahrig (2019) DIBH-VMAT for Consolidation RT in Mediastinal B-NHL can Significantly Reduce Doses to OAR Report of Two Cases. Int J Radiol Imaging Technol 5:043. doi.org/10.23937/2572-3235.1510044

Copyright

© 2019 Fahrig A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

CASE REPORT | OPEN ACCESS DOI: 10.23937/2572-3235.1510044

DIBH-VMAT for Consolidation RT in Mediastinal B-NHL can Significantly Reduce Doses to OAR Report of Two Cases

Antje Fahrig, PD1*, Th Koch1, Ch Heine, MSc1, M Lenhart2 and L Fischer von Weikersthal3

1Radiation Oncology Department, Klinikum Bamberg, Sozialstiftung Bamberg, Germany

2Radiology Department, Klinikum Bamberg, Sozialstiftung Bamberg, Germany

3Hematology and Oncology Department, Gesundheitszentrum St. Marien GmbH, Klinikum St. Marien Amberg, Germany

Abstract

Background

Consolidative radiotherapy after immuno-chemotherapy in localized bulky diffuse large B-cell lymphoma (DLBCL) patients significantly improves both, overall and progression-free survival and treatment is in principle curative. Therefore protection of organs at risk is highly relevant.

Case, planning and results

Two 53-years and 18-years old patients with bulky mediastinal DLBCL were planned with and without deep inspiration breath-hold (DIBH) and volumetric modulated arc therapy (VMAT). DIBH reduced the doses to the heart and the lungs while homogeneity and conformity were not compromised. The number of Monitor Units (MU) needed was significantly reduced by DIBH-VMAT. Both patients were treated in DIBH-VMAT.

Conclusion

Planning with DIBH in bulky mediastinal DLBCL is feasible and should be taken into account due to the high relevance with regard to acute and late toxicity.