Espinosa de los Monteros Pérez LE, Jimsénez Rojas LV, Gómez-Barreto D, Vázquez Moreno JA (2019) Frequency andc Characterization Meningococcal Carriage Isolates, among Prisoner's Inmates from Mexico City. J Infect Dis Epidemiol 5:082.


© 2019 Espinosa de los Monteros Pérez LE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

RESEARCH ARTICLE | OPEN ACCESS DOI: 10.23937/2474-3658/1510082

Frequency and Characterization Meningococcal Carriage Isolates, among Prisoner's Inmates from Mexico City

Luz Elena Espinosa de los Monteros Pérez1*, Jiménez Rojas LV2, Gómez-Barreto D2 and Vázquez Moreno JA3

1Hospital General Dr. Manuel Gea Gonzalez, Microbiology Research Laboratory, Mexico

2Pediatric Hospital of Mexico, Infectology, Mexico

3National Reference Laboratory for Meningococci, Carlos III Institute of Health, Spain


Meningococcal disease in Mexico has a very low incidence; it is one of the countries with few reported cases as prevalence of the carrier state is unknown. Some studies have shown that many invasive meningococcal diseases are restricted to a specific number of hyper-virulent strains that contrast with carrier isolates. The aim of this study was to determine the frequency and characterization of meningococcal carriage isolates among prisoner's inmates. Nasopharyngeal swabs were obtained, Neisseria meningitidis was identified by standard methods, Polymerase Chain Reaction, and penicillin susceptibility was carried out. Multilocus Sequence Typing was performed as well. The study included 461 inmates. The overall carrier frequency was 10.41%, serogroups were isolated: B (20), C (17), Y (8) and nongroupable (3), 70.8% (34/48) of isolates showed some level of resistance to penicillin. Genetic diversity among isolates is observed and the presence of hypervirulent clones was demonstrated as ST42/44 CC and ST11/ET37CC.