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Infectious Diseases and EpidemiologyISSN: 2474-3658

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 Open Access DOI:10.23937/2474-3658/1510190

COVID-19 Responses: Unintended and Undiscussed Potential Consequences

Joel B Epstein, DMD, MSD, Sean Mark, PhD and Richard G Mathias, MD, PhD

Article Type: Commentary | First Published: January 30, 2021

With the focus upon “flattening the curve”, ongoing non-COVID-19 medical care needs have been displaced and care delayed. These have included oncology care and cardiac care, and research interruption and delay as examples of unintended consequences of the COVID-19 response, the implications of which will be realized in upcoming years. Reduction in health care productivity due to infection control recommendations that increase time of preparation and increase time of providers and staff and t...

 Open Access DOI:10.23937/2474-3658/1510189

Detection of Measles IgM and Malaria Parasite among Febrile Children in Zaria, Nigeria

Maryam Aminu, Yakubu Irimiya Parason, Umar Abdullahi, Mohammed Ibrahim Tahir, Fatai Akindele Olaniyan and Mohammed Aminu Usman

Article Type: Research Article | First Published: January 30, 2021

Measles and malaria are highly infectious diseases worldwide and are of major public health concern. Although measles is a leading cause of death of young children in many developing countries, it is vaccine preventable. This study was carried out to determine the seroprevalence of measles IgM as well as the prevalence of malaria parasite among febrile children attending Ahmadu Bello University Medical Center, Samaru Zaria, Nigeria. A total of 80 blood samples purposively and randomly collected ...

 Open Access DOI:10.23937/2474-3658/1510188

Latent Tuberculosis Treatment in People Living with HIV/ AIDS in Algeria, Time to Act: A Review

Ouyahia Amel, Rais Mounira, PhD, Gasmi Abdelkader, PhD, Kouicem Aya Tinhinane, Kouicem Mohamed Safir and Lacheheb Abdelmadjid

Article Type: Review Article | First Published: January 28, 2021

In 2017, World Health Organization (WHO) estimates that 920000 of People living with HIV/AIDS (PLWHA) developed tuberculosis disease worldwide, which is the number one infectious killer of PLWHA. To the end of 2019 there are an estimated 13000 PLWHA in Algeria, the estimated rate of the killing couple HIV-tuberculosis in 2018 was 14.7% (276 cases). We aimed in this review article to report the current situation of management of LTBI in Algeria, highlight the net gain of such treatment in PLWHA a...

 Open Access DOI:10.23937/2474-3658/1510187

Overview of the Rationale for L-Glutamine Treatment in Moderate-Severe COVID-19 Infection

Adebola Okunola E Obayan, MD, PhD (Surgery), FRCSC

Article Type: Original Article | First Published: January 13, 2021

This overview focuses on how to overcome the treatment challenges posed by COVID-19 infection and reduce mortality with antioxidant therapy. The rationale for this treatment approach is explored by addressing the following objectives. COVID-19 is the viral pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (WHO). SARS-CoV-2 is an enveloped positive- sense virus in the RNA beta Coronavirus family. Identifying a definitive treatment for COVID-19 infection and...

 Open Access DOI:10.23937/2474-3658/1510186

Risk Factors, Seroprevalence and Infectivity of Hepatitis B Virus amongst Children Resident in Orphanages in a Developing Country

Chioma Paulina Ogbonna, MBBS, FMCPaed, Christian Chukwukere Ogoke, MBBS, FWACP, Anthony Nnaemeka Ikefuna, MBBS, FMCPaed, FRCP, Tochukwu Chukwukadibia Ezeofor, MBBS, FMC, FMCpaed, Emeka Charles Nwolisa, MBBS, FWACP, FRCP, Franklin Chime Emerenini, MBBch, FMCpaed, and Christopher Bismarck Eke MBBS, FWACP

Article Type: Original Article | First Published: January 13, 2021

Hepatitis B infection (HBV) remains a significant clinical and public health problem and is hyperendemic in Nigeria. In highly endemic regions, infections spread from mother to child, or by horizontal transmission, with the burden of infection being highest in under-fives. Nigeria has a large number of orphans and vulnerable children, with reports of high seroprevalence of HBV infection in orphanages. There is no such report from our locality, despite having a high number of orphans. Therefore, ...

 Open Access DOI:10.23937/2474-3658/1510185

Antibiotic De-escalation Practice in General Intensive Care Unit Penang General Hospital

Shiao Hui Lim, Chen Chuan Kuai and Chew Har Lim

Article Type: Research Article | First Published: January 11, 2021

De-escalation of empirical antibiotic therapy according to results of microbiological cultures will effectively target the causative pathogen, besides reducing broad-spectrum antibiotic exposure and minimizing the selection pressure on the development of resistant microorganisms. Primarily, the study aimed to assess the practice of broad-spectrum antibiotic de-escalation in General Intensive Care Unit (GICU). Secondary objectives were to describe the indication of broad-spectrum antibiotics use,...

Volume 7
Issue 1