This article reports a left cerebellopontine angle glioblastoma presenting with two week history of rapidly progressive hearing loss and trigeminal pain, treated by subtotal resection and radiotherapy with concomitant and adjuvant temozolomide. At one year, local tumor control and diffuse neoplastic seeding in the cervical spinal cord were evidenced.

Glioblastomas involving the cerebellopontine angle are exceptional with only 10 reported cases. The possibility of a glioblastoma should be considered in the differential diagnosis of malignant cerebellopontine angle tumors. The standard treatment including maximum tumor resection and Stupp protocol is justified to obtain local tumor control.