An overview and commentary are presented on the role of stress and glucocorticoids in the pathogeny of age-related psychiatric and neurologic disorders, first of all depressive illness and Alzheimer's disease. The connections of these disorders with senescence-induced changes in bioregulation of hypothamo-pituitary-adrenal axis activity are discussed, focusing attention on biphasic glucocorticoid effects, gender differences, adverse effects of exogenous corticosteroids and the importance of stre...

The aim of this systematic review was to review the recent literature regarding the effect of heat waves on mortality in elderly adults. A systematic search of the literature, was conducted by two reviewers during March 2018, using three electronic databases (PubMed, Web of Science, and Scopus). The PRISMA guidelines were used for the quality assessment of the published studies. The literature search identified a total of 345 articles, while only 24 studies met the inclusion criteria and were in...

The proportion of older people in the Australian population is increasing, heralding a change in how illness presents as well as the profile of people presenting with illness. This changing disease profile is most strikingly observed in conditions which disproportionately affect the old and particularly the oldest old. It is exemplified by stroke which is a leading cause of death and disability in Australia with 70% of stroke patients aged 65 and older....

The purpose of this case study is to share an innovative program developed for Registered Nurses (RNs) working in long-term care settings in the Midwest region of the United States and outcomes of the Geriatric Nurse Leadership Academy for Long-Term Care (Leadership Academy). In the United States, the growth of the population over the age of 65 and the need to quality and competent care in long term care has grown exponentially. The Leadership Academy was developed as one component of a research...