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Review Article  |   Volume 3, Issue 11

Acute Disseminated Encephalomyelitis (ADEM) Secondary to Neurosyphilis

Ryan Kahn, Christopher Dermarkarian, Elizabeth Crocco, Gabrielle Yeaney and Marcia Williams
Abstract

Acute disseminated encephalomyelitis (ADEM) is a rare autoimmune demyelinating disease of the central nervous system. For our case presentation, a 52-year-old Hispanic male presented with altered mental status and focal neurological defects. MRI showed multiple lesions scattered throughout the brain. VDRL and FTA-ABS was positive in the CSF. Brain biopsy demonstrated foamy macrophages, loss of myelin, and perivascular T cells. The diagnosis was acute disseminated encephalomyelitis secondary to neurosyphilis.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410143

Review Article  |   Volume 3, Issue 11

Neonatal Polycythemia: A Review

S Umit Sarici, Murat Ozcan and Demet Altun
Abstract

Polycythemia in the newborn is defined as either venous hematocrit or hemoglobin levels above 65% and 22 g/dl, respectively. Its incidence is reported between 1 to 5%. In this article definition and epidemiology of polycythemia, physiological changes in postnatal hematocrit levels, relationship between polycythemia and hyperviscosity, pathophysiology and diagnosis of polycythemia, etiology, clinical signs and complications of polycythemia with a special emphasis on treatment algorithms and long-term neurodevelopmental outcome considering all current review articles and meta-analyses are reviewed.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410142

Case Report  |   Volume 3, Issue 11

Thyroid Metastasis from Colorectal Cancer: A Case Report and Review of Literature

Mennet A, De Blasi V, Simone G, Mormont M and Morel P
Abstract

A 68-year-old man with sigmoid carcinoma was initially treated by surgical resection and adjuvant chemotherapy. Two years later, he was admitted to the hospital for recurrence of his disease with iliac parietal nodules and nodules in the recto-vesical pouch. Follow-up imaging with 18-Fluoro-2-Deoxy-D-Glucose Positron Emission Tomography (18-FDG PET) showed a focal increased uptake in the left side of the neck at the level of the thyroid gland and the absence of lung or liver metastases.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410141

Case Report  |   Volume 3, Issue 11

An Ileal Perforation Associated with Extended Spectrum β-Lactamases-Producing Escherichia Coli: Medical Case Report

Michael Owusu, Augustina Annan, Nimako Sarpong, Ellis Owusu-Dabo, Yaw Adu-Sarkodie, Kwadwo Sarfo Marfo, Isaac Osei and Kofi Tawiah Mensah
Abstract

Intestinal perforation is one of the leading fatal causes of death among individuals mostly in developing countries. Although many reports have associated perforations with typhoid infections, reports on the role of other bacterial pathogens especially resistant strains in causing ileal perforations are limited. We report a rare case of ileal perforation associated with extended-spectrum beta-lactamase (ESBL) - producing Escherichia coli (E. coli) in Ghana.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410140

Case Report  |   Volume 3, Issue 11

Transcatheter Closure Combined with Antibiotic Therapies for Patients with Infective Endocarditis and Congenital Heart Disease

Boli Ran, Minfeng Li, Yeqing Li, Yang Lin, Weimin Liu, Qiulin Luo, Yongxin Fu, Qianmei Tang, Ya Yang and Yunfei Pu
Abstract

The experience of transcatheter closure combined with antibiotic therapies at our cardiovascular center was retrospectively analyzed in 5 cases of infective endocarditis with congenital heart disease. Transcatheter closure was performed at least 7 to 10 days after the patient's body temperature had recovered normal following effective antibiotic therapies, and after cardiac vegetations were not detected by echocardiography.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410139

Case Series  |   Volume 3, Issue 11

Percutaneous Coronary Intervention for Single Coronary Artery: Two Case Studies

Yang Zhuo, Yu-qi Fan, Zhao-fang Yin, Li Fan, Zhi-hua Han, Chang-qian Wang and Zuo-jun Xu
Abstract

Single coronary artery (SCA), a congenital and rare anomaly, is defined as a coronary artery arising from the sinus of valsalva and supplying the entire heart. According to modified Lipton's classification criteria, L-1 subtype is the rarest type of SCA. Here we present two L-I subtype cases. In case one, one of the side branches from the first septal artery proceeded as the right coronary artery (RCA). In case two, the distal septal artery and distal circumflex artery together served as the RCA. Both two patients underwent percutaneous coronary intervention because of unstable coronary artery disease.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410138

Case Report  |   Volume 3, Issue 11

Unresolved Issues concerning Inadequate Immune Response after Rabies Post-Exposure Prophylaxis in an Immunocompromised Patient

Rana Shibli and Shmuel Rishpon
Abstract

We present an immunocompromised patient with inadequate immune response to the rabies post exposure prophylaxis (PEP), and our management strategy after this inadequate response. Currently, evidence based strategy for action after failure of PEP is partial. Since the prevalence of immunocompromised patients is increasing, further studies and guidelines are necessary.

  PDF   |    Full Text | DOI: 10.23937/2378-3656/1410137