Factors Affecting Early Postoperative Visual Acuity in Cataract Patients with High Myopia
Rongrong Zhang, Fu Li, MD, Yan Yu, Tiantian Wang, Changfan Wu
Article Type: Research Article | First Published: August 22, 2020
To analyze the short-term results of cataract surgery in patients with high myopia and determine the risk factors responsible for early postoperative visual outcome. A total of 93 patients (115 eyes) with high myopia who underwent phacoemulsification and intraocular lens (IOL) implantation were enrolled in this retrospective study. Complete ophthalmologic examinations were performed preoperatively and postoperatively. According to the best-corrected visual acuity (BCVA) at one week after surgery...
Contrast Sensitivity Studies and Test- A Review
Pateras E and Karioti M
Article Type: Review Article | First Published: June 11, 2020
Contrast sensitivity (CS) expresses the quality of human vision. This article presents the main points for the interpretation of CS and what structures of the eye and brain contribute to achieving it. There is still information on the ways and types of CS clinical examination, factors and conditions affecting it, and the latest technological developments in its measurement. Visual acuity (V.A.) is the measure of the spatial resolution of the eye (the clarity or sharpness of vision) and its measu...
Choroidal Metastases as the First Manifestation of Recurrence of Breast Carcinoma
Susana Henriques, Susana Almeida Baptista, Fernando Trancoso Vaz, Mara Ferreira and Isabel Prieto
Article Type: Case Report | First Published: June 05, 2020
Choroidal metastases are the most frequent malignant intraocular tumor. In most cases, they arise after identification of the primary tumor and are associated with involvement of other organs. Less frequently, the ocular lesion may be the first presentation of a primary tumor or relapse of primary disseminated tumor. We present a case of choroidal metastasis as the first manifestation of recurrence of a breast tumor, diagnosed 4 years earlier. We analyze the clinical presentation, ancillary diag...
Neurodevelopmental Disabilities in Children with Retinopathy of Prematurity: A Report from India
Nagamani Beligere, MD, MPH, Vijayalakshmi Perumalsamy, MD, Jeyaseeli H Flora, MS and Marla J Garska, MS
Article Type: Research Article | First Published: March 30, 2020
We assessed the neurodevelopment, visual and neurological outcomes among children with a diagnosis of ROP referred to an ophthalmic center in India between 2014-2016. Neurodevelopmental status was assessed using skills inventory, for premature and primary school children who are blind and visually impaired. Visual and motor coordination status was assessed using Buketencia Developmental Test of Visual Motor Integration....
Resolution of Intraocular Lens Precipitates with Topical Corticosteroids
Tanner J Ferguson, MD, Jordan D Deaner, MD, Craig See, MD, and Careen Y Lowder, MD, PhD
Article Type: Case Report | First Published: March 30, 2020
We describe a case of a patient who developed late-onset intraocular lens (IOL) cellular precipitates 8 months after IOL placement. The patient had a history of clinically inactive toxoplasmosis and developed visually significant IOL precipitates 8 months after uncomplicated cataract surgery with a previously unremarkable postoperative course without other signs of ocular inflammation. The IOL deposits improved and resolved with use of topical steroids, which coincided with an improvement in vis...
Proteasome and Autophagy Pathway in Corneal Epithelial Cells with Limbal Stem Cell Deficiency
Fawzia Bardag-Gorce, Michael Di Lorenzo, Robert Niihara, Sarah Sunada, Amanda Laporte, Kavita Narwani, Daileen Cortez, Jeremy Stark, Mynor Garcia, Alissa Diaz, Joan Oliva, Richard Hoft, and Yutaka Niihara
Article Type: Original Article | First Published: February 28, 2020
Immunofluorescent staining showed that both pathways were positive in normal corneal epithelium. However, while proteasome subunits were decreased in LSCD-CEC, autophagy biomarker MAPLC3B and ATG12-ATG5 complex were significantly increased in LSCD-CEC, compared to healthy CEC. These results indicate that LSCD-induced impairment of UPP may cause a compensatory stimulation of autophagy. However, despite autophagy up regulation, damaged and unwanted proteins, such as modified keratin K4 and K13 agg...