International Journal of

Ophthalmology and Clinical ResearchISSN: 2378-346X

Current Issue

 Open Access DOI:10.23937/2378-346X/1410101

Failure to Complete Induction in Anti-VEGF Therapy for Neovascular Age-Related Macular Degeneration

Joel Hanhart, Doron S Comaneshter and Shlomo Vinker

Article Type: Research Article | First Published: December 21, 2018

To evaluate the proportion and characteristics of patients diagnosed with neovascular age-related macular degeneration (AMD) who do not complete the loading dose of bevacizumab, given as first line agent. Using the electronic medical records of all patients affiliated to the largest health maintenance organization in Israel who received intravitreal injections of bevacizumab between September 2008 and October 2014, we isolated patients aged of 60 years or more treated for neovascular age-relate...

 Open Access DOI:10.23937/2378-346X/1410100

Circumferential Pupillary Capture by IOL due to Intraocular Gas Tamponade: A Case Report

Mesut Erdurmuş, Uğur Acar and Güngör Sobacı

Article Type: Case Report | First Published: December 21, 2018

A 55-years-old female presented with pain in the right eye for 15 days. She had a history of complicated cataract surgery followed by pars plana vitrectomy, intraocular gas injection and sulcus fixated intraocular lens implantation. On ophthalmologic examination, pupillary capture by intraocular lens, shallow anterior chamber, corneal edema and elevated intraocular pressure despite maximum medical therapy was observed. Intraocular gas induced secondary pupillary block glaucoma diagnosis was made...

 Open Access DOI:10.23937/2378-346X/1410099

Association of Various Systemic Factors with Intraocular Pressure

Pragati Garg, Mohit Gupta, Swati Yadav, Luxmi Singh and Bharti Nigam

Article Type: Research Article | First Published: December 21, 2018

Raised intraocular pressure (IOP) is the principal modifiable risk factor for the development and progression of glaucoma. Glaucoma is defined as progressive optic neuropathy, based on visual field loss and/or optic disc findings, is more likely to be associated with elevated intraocular pressure (IOP), although IOP is not the only risk factor for glaucomatous optic nerve damage. The complex physiology involved in aqueous humor formation and its maintenance indicates its dependence on other syst...

 Open Access DOI:10.23937/2378-346X/1410093

Thorough Perioperative Laser Photocoagulation in Prevention of Neovascular Glaucoma after Vitrectomy for Diabetic Macular Edema

Yuka Aoyama-Araki, Fumiyuki Araki, Tomoyasu Shiraya and Satoshi Kato

Article Type: ORIGINAL RESEARCH | First Published: September 20, 2018

Neovascular glaucoma (NVG) is a severe complication that may follow pars plana vitrectomy (PPV) for diabetic macular edema (DME). The objective of this study was to evaluate the effectiveness of perioperative fluorescein angiography (FA) and targeted photocoagulation of the non-perfused area (NPA) in preventing the occurrence of postoperative NVG....

 Open Access DOI:10.23937/2378-346X/1410092

Giant Sebaceous Cell Carcinoma of Upper Eyelid - Case Report

Santosh Singh Patel, Reshu Malhotra, ML Garg, AK chandrakar and Dhanshree Kalway

Article Type: CASE REPORT | First Published: September 19, 2018

An eighty-year-old patient presented with right upper eyelid mass. Contrast enhanced computed tomography (CECT) showed large heterogeneously enhancing exophytic soft tissue density mass lesion with few hyperdense foci noted involving skin and subcutaneous tissue. An excisional biopsy was performed. A diagnosis of sebaceous cell carcinoma was confirmed on histopathology....

 Open Access DOI:10.23937/2378-346X/1410091

Iron-Overload, Oxidative DNA Damage and Differential Transcript Expression of Iron Homeostasis Genes in Human Cortical Cataracts

Sankaranarayanan Rajkumar, Nair Gopinathan Vidya, Darshini Ankit Ganatra and Abhay Raghukant Vasavada

Article Type: ORIGINAL RESEARCH | First Published: September 10, 2018

The purpose of the study is to determine the level of iron, its role in oxidative damage and to profile and measure the level of transcript expression of genes responsible for iron homeostasis in lenses of human cataracts. Human whole lenses (WLs) were obtained from donors' eyes (n = 33) within 8 hours of death. A total of 167 (control, n = 35 and cataract, n = 132) anterior central capsules (ACC) harboring lens epithelial cells (LECs) and lens aspirate containing LECs, primary and secondary len...

 Open Access DOI:10.23937/2378-346X/1410090

Therapeutic Efficacy of Subthreshold Laser Photocoagulation using a Conventional Pattern Scan Laser for Macular Edema in a Retrospective Study

Tomoyasu Shiraya, Satoshi Kato and Fumiyuki Araki

Article Type: Original Research | First Published: August 11, 2018

Subthreshold laser photocoagulation has emerged and is changing minimally invasive treatment for macular edema (ME) affected by retinal vascular diseases. However, this laser method requires specific photocoagulator, and it cannot be introduced at each facility. We investigated the efficacy of subthreshold laser photocoagulation using a conventional pattern scan laser (PS-STLT) in treating ME in clinical practice....

 Open Access DOI:10.23937/2378-346X/1410089

Unusual Laser Blepharoplasty Complications: Sight and Life-Threatening!

Nazrin Nordin and Lott Pooi Wah

Article Type: Clinical Image | First Published: August 11, 2018

A 53-years-old woman presented with bilateral severe periorbital swelling and reduce left eye visual acuity. She had undergone laser blepharoplasty 1 week prior to presentation. Ophthalmic examination revealed both eye periorbital swelling with pouring pus discharge from lower lid with underlying erythematous and ulcerative skin, limitation of extraocular muscles and chemosis....

Volume 5
Issue 3