Sayin S (2019) The Relation between Helicobacter Pylori Density and Gastritis Severity. Int Arch Intern Med 3:019.


© 2019 Sayin S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Research Article | OPEN ACCESS DOI: 10.23937/2643-4466/1710019

The Relation between Helicobacter Pylori Density and Gastritis Severity

Serhat Sayin*

Department of Internal Medicine, Training and Research Hospital, Aksaray University, Turkey



Helicobacter Pylori affects many individuals in developing countries. Inflammation caused by helicobacter Pylori differs depending on the virulence factors, density and host tissue response of the bacteria. This study is intended to investigate the relation between density of helicobacter Pylori colonization in gastric mucosa in biopsy specimens and gastric mucosal inflammation severity.

Materials and methods

Our study included 685 patients who applied to the hospital with dyspeptic complaints and had gastroscopy between the dates of January the 1st 2017 and January the 1st 2018. Histopathologic results of endoscopic biopsy specimens of these patients were retrospectively screened. Inflammatory severity and helicobacter Pylori intensity were assessed by Sydney scoring.


68.6% of the patients were infected with Helicobacter Pylori. As the intensity of inflammation increased, the intensity of Helicobacter Pylori increased as well. The relation between the intensity of Helicobacter Pylori and the severity of inflammation was statistically significant (p < 0.001).


Helicobacter Pylori infection increases gastric inflammation.