International Archives of Internal Medicine is an international, open access, peer reviewed journal focused to enhance the knowledge in the field of medicine covering a wide range of conditions affecting the internal organs of the body - the heart, the lungs, the liver and gastro-intestinal tract, the kidneys and urinary tract, the brain, spinal column, nerves, muscles and joints. Internists also deal with some diseases specifically affect individual organs, the majority of common diseases - arteriosclerosis, diabetes, high blood pressure and cancer may affect many internal organs of the body.

With respect to multidisciplinary approach in research, this journal fosters an environment for physicians, to publish their works on topics, acute medicine, cardiology, clinical genetics, clinical neurophysiology, clinical pharmacology and therapeutics, dermatology, endocrinology and diabetes mellitus, gastroenterology, general medicine, genito-urinary medicine, geriatric medicine, hematology, immunology, infectious diseases, medical oncology, ophthalmology, neurology, nuclear medicine, pediatric cardiology, palliative medicine, pharmaceutical medicine, rehabilitation medicine, renal medicine, respiratory medicine, rheumatology, sport and exercise medicine, tropical medicine, etc.

Journal Information

Title: International Archives of Internal Medicine

ISSN: 2643-4466

Editor-in-chief: Photios Anninos

NLM title abbreviation: Int Arch Intern Med

ISO abbreviation: Int Arch Intern Med

Other titles: IAIM

Category: Medicine

DOI: 10.23937/2643-4466

Peer review: Double blind

Review speed: 3 weeks

Fast-track review: 10 days

Publication format (s): Electronic and print

Publication policy: Open Access; COPE guide

Publication type(s): Periodicals

Publisher: ClinMed International Library

Country of publication: USA

Language: English

Contact email:

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI


 Open Access DOI:10.23937/2643-4466/1710028

Elderly Involvement in the Era of COVID-19 Infection

Maha Hossam Eldin Ibrahim and Abeer Awad Abdellatif

Article Type: Review Article | First Published: September 14, 2020

Nowadays, the entire world is facing the outbreak pandemic of COVID-19 infection which is a lethal infection to some extent. The most commonly affected group of population is the elderly due to impaired immunity and multiple co-morbidities they suffer from. From this point of view; we will discuss some important issues about the elderly involvement during COVID-19 pandemic hoping to raise the awareness toward that frail sector of population. Indeed many researches for COVID infection whether reg...

 Open Access DOI:10.23937/2643-4466/1710027

A Potential Non-Invasive Therapy to Treat COVID-19, As Yet Unrecognized in the Medical Literature

Benjamin J Scherlag, PhD, Ronald A Scherlag, BS, MBA and Sunny S Po, MD, PhD

Article Type: Commentary | First Published: September 05, 2020

As the pandemic rages across the globe, we await the proven safe and effective vaccine that will turn the tide against the novel coronavirus SARS-CoV-2 (a.k.a. COVID-19) spread. In the meantime, a number of pharmaceutical agents have been the subject of studies including, Hydroxychloroquine, Remdesivir, Dexamethasone, among others with varying degrees of clinical efficacy. Hidden from the medical literature is the evidence gathered by investigators for more than a decade that negative air ions c...

 Open Access DOI:10.23937/2643-4466/1710026

Comparison of Health Status between At-Home-Care and Institutionalized Adults with Down Syndrome in Japan

Kimiko Ueda, MD, MPH, PhD and Nobuhiko Okamoto, MD

Article Type: Research Article | First Published: May 02, 2020

In both cohorts, more than half of the subjects, regardless of gender, had dyslipidemia. Hyperuricemia and obesity were significantly more frequent in at-home-care men than in institutionalized men. The most common diseases in the institutionalized subjects were dyslipidemia (61%), ringworm (59.3%), hypothyroidism (30.5%), hyperuricemia (25.4%) and dementia (16.9%; 46% in those in their 60s). Subjects in their 50s or later showed a greater need for assistance in walking/moving, getting dressed a...

 Open Access DOI:10.23937/2643-4466/1710025

Sebaceous Carcinoma of the Vulva: Case Report and Review of Literature

Rama P Namuduri, Mihir Gudi and Soo Kim Lim Tan

Article Type: Case Report | First Published: May 02, 2020

Extraocular sebaceous carcinoma is an uncommon malignant tumor that usually affects the head and neck. Despite being rich in sebaceous glands, vulvar sebaceous carcinoma is extremely rare. We report a case of vulvar sebaceous carcinoma in a 64-year-old woman that presented as an asymptomatic nodule and was successfully treated by wide local excision. The number of reported cases of vulvar sebaceous carcinoma is very small, more cases need to be collected in order to identify prognostic factors a...

 Open Access DOI:10.23937/2643-4466/1710024

Progress and Challenges of Global High-Resolution Endoscopy

Sheena Bhushan, Rebecca Richards-Kortum and Sharmila Anandasabapathy

Article Type: Review Article | First Published: April 23, 2020

In recent years, gastrointestinal endoscopy has seen an influx of high-resolution endoscopic technologies that are capable of providing optical biopsies of the epithelial surface in real time. Upcoming high-resolution endoscopy techniques are CLE, OCT, EC and HRME. Powered by automated diagnostic algorithms and more-cost effective alternatives, these high-resolution endoscopic technologies have the potential to not only facilitate real-time decision making, but also improve screening and surveil...

 Open Access DOI:10.23937/2643-4466/1710022

Serpentine Supravenous Eruption Docetaxel Related Diagnosed by Teledermatology

Nuria Barrientos Perez, MD, Patricia Ibeas Millan, MD and Jose Domingo Dominguez Aunon, PhD

Article Type: Case Report | First Published: February 28, 2020

Serpentine supravenous dermatitis is a rare eruption related with cytotoxic drug infusion. Several chemotherapeutic agents have been related with this entity. But, most of the published cases are caused by docetaxel. However, considering the high frequency of administration in oncology this rather unknown eruption should be known to all physicians, especially oncologist, dermatologist, internist and GP....

 Open Access DOI:10.23937/2643-4466/1710023

Stress from Uncertainty Predicts Resilience and Engagement among Subspecialty Medicine Fellows

Arabella L Simpkin, MD, MMSc, Susan Hata, MD, Merranda Logan, MD, MPH and Katrina A Armstrong, MD, MSCE

Article Type: Research Article | First Published: March 28, 2020

Burnout is an accelerating phenomenon in the healthcare environment, with implications for physician wellbeing, patient safety, and the quality of healthcare. The ability to manage uncertainty has been identified as a potentially important determinant of burnout in physicians and is now a recognized competency for trainees. No prior studies have evaluated the association of fellows’ reaction to uncertainty with burnout metrics, including resilience and engagement. Cross-sectional online survey...

 Open Access DOI:10.23937/2643-4466/1710021

Peripheral Neuropathy as Initial Manifestation of Churg- Strauss Syndrome

Antonio Villa, MD

Article Type: Case Report | First Published: November 23, 2019

Peripheral neuropathies are well-known complications of primary systemic vasculitides. Antineutrophil cytoplasmic antibody (ANCA)-associated small vessel systemic vasculitides and medium-sized vessel vasculitis are known to frequently damage the peripheral nervous system. A 47-year-old man had a fifteen day history of pain in his lower and upper limbs associated to paresthesias and hypostenia. His medical history revealed no history of asthma, but in the last year some episodes of obstructive- c...

 Open Access DOI:10.23937/2643-4466/1710020

Clinical Conundrums in Diagnosis and Management of Multisystem Langerhans Cell Histiocytosis

Jun Park, MD and Vishal Sehgal, MD

Article Type: Case Report | First Published: September 26, 2019

Langerhans Cell Histiocytosis (LCH) is a rare disorder with an incident of 1.8 cases per 1,000,000. It involves granulomatous deposits in multiple organs, leading to a wide variety of manifestations such as bone lesions, pulmonary nodules, pituitary lesions, and skin lesions. With mucocutaneous manifestation, it is often diagnosed in childhood, typically making LCH a childhood disease. However, due to the involvement of multiple organ systems and variable clinical courses, if not diagnosed durin...

 Open Access DOI:10.23937/2643-4466/1710019

The Relation between Helicobacter Pylori Density and Gastritis Severity

Serhat Sayin

Article Type: Research Article | First Published: September 21, 2019

Helicobacter pylori affects many individuals in developing countries. Inflammation caused by helicobacter pylori differs depending on the virulence factors, density and host tissue response of the bacteria. This study is intended to investigate the relation between density of helicobacter pylori colonization in gastric mucosa in biopsy specimens and gastric mucosal inflammation severity. Helicobacter pylori (H. pylori/Hp) is a microaerophilic gram negative bacilli initially detected in the antra...

 Open Access DOI:10.23937/2643-4466/1710018

A Review of the Most Common Dermatologic Conditions and their Debilitating Psychosocial Impacts

Madeeha Mian, BA, Annika S Silfvast-Kaiser, MD, So Yeon Paek, MD, Dario Kivelevitch, MD and Alan Menter, MD

Article Type: Review Article | First Published: July 22, 2019

The majority of skin conditions are not life-threatening; however, many can be severe and disfiguring enough to devastate a patient's quality of life. Skin diseases can significantly impact not only a patient's physical appearance, but also their social and emotional well-being. Even the smallest skin lesions have been shown to disrupt a person's level of overall wellness. Here, we aim to address the potential psychological and emotional impact of the most common and debilitating dermatologic co...

 Open Access DOI:10.23937/2643-4466/1710017

Effect of Vitamin D on Novel Ventricular Repolarization Indices

Hakan Kaya

Article Type: Research Article | First Published: July 19, 2019

Vitamin D deficiency may be the underlying cause of most health issues and diseases. There are few studies investigating the effect of low vitamin D levels on the cardiac arrhythmias. The electrocardiographic Tpeak to Tend (Tpe) interval and Tpe/QT ratio may associate with increased ventricular arrhythmias. The goal of this study was to evaluate the relationship between ventricular repolarization and vitamin D levels in apparently healthy individuals by using Tpe interval, Tpe/QT ratio and Tpe/c...

 Open Access DOI:10.23937/2643-4466/1710016

Disclosure: Possibility to Discuss Medical Error

Vitor S Mendonca and Maria Luisa S Schmidt

Article Type: Research Article | First Published: July 03, 2019

The study intended to analyze physician's post medical error disclosure process. This is a qualitative understanding research with ten Brazilian physicians from a private hospital. Participants were interviewed following a semi-structured script. From the data obtained in this research, results indicated that the surgical specialties or those in related fields had a higher error incidence. Classical medical training further reinforces a specific behavior by physicians that makes it difficult to ...

 Open Access DOI:10.23937/2643-4466/1710015

The Impact of the Medical Education on Student's Knowledge, Opinion and Attitude to Organ/Tissue Donation-Transplantation

Serpil Demirag, MD, PhD

Article Type: Research Article | First Published: July 03, 2019

The purpose of this study is to investigate the effect of medical education and training on medical student's knowledge, thoughts and attitudes to organ donation and transplantation, and also to draw attention to the subject. Totally 323 first and sixth grade students were included in this study. A questionnaire consisting of four categories and 48 questions was used to collect data. SPSS 18.0 program was used for the data input and the analyses of the study. A p value smaller than 0.05 was acce...

 Open Access DOI:10.23937/2643-4466/1710014

Correlation between the Number and Magnitude of Howship Lacunes (HL) with the Blood Concentration of C-Ipth and CT in Patients with Advanced Chronic Kidney Disease Treated and Non-Treated with Regular Haemodialysis

Petar Cakalaroski, Ljutvi Zulbeari and Koco Cakalaroski

Article Type: Research Article | First Published: July 03, 2019

Seventy-one patients (71) with chronic kidney disease (CKD) (21 men and 18 females non-treated with hemodialysis and 19 men, respectively 13 females treated with regularly repeated hemodialysis) are investigated. The mean clearance of creatinin in investigated group were 0.17 mL/sec (10.2 mL/min). The average age of non-dialyzed group were 40.3 years, and in the dialyzed patients -38.6 years....

 Open Access DOI:10.23937/2643-4466/1710013

Phases of the Diagnostic Journey: A Framework

Linda N Geng, Oliver Sum Ping and Yong-Jian Geng

Article Type: Commentary Article | First Published: May 20, 2019

Diagnostic journeys begin when patients first present to a healthcare provider for their symptoms and end when they receive the correct diagnosis for these symptoms. In many cases, the diagnosis can be made promptly, but patients with rare, complex, or unusual conditions often embark on odysseys spanning years to sometimes even decades in search of a diagnosis. This prolonged process can often result in excessive costs, preventable medical errors and iatrogenesis, as well as feelings of frustrat...

 Open Access DOI:10.23937/2643-4466/1710012

Acute Epiploic Appendagitis: Report of Six Cases and Review of Literature

Antoine El Khoury, Majd Roustom, Henri Azar, Georges Chaer and Tony El Murr

Article Type: Case Report | First Published: May 01, 2019

Appendagitis has always been considered as a diagnosis of exclusion. Most of the times it is diagnosed incidentally. The majority of patients present flank pain, right and/or left iliac fossa pain with few other symptoms. These findings lead usually the physician toward a surgical disease. Imaging is very important to confirm the diagnosis of appendagitis and to avoid unnecessary hospitalizations and surgeries. In this article, we present five cases of acute appendagitis that have had nearly sim...

 Open Access DOI:10.23937/IAIM-2017/1710011

Spontaneous Coronary Artery Dissection: An up to Date

Dario Buccheri and Daniele Adorno

Article Type: Commentary article | First Published: February 20, 2019

Spontaneous dissection of the coronary artery (SCAD) is an uncommon cause of acute coronary syndrome (ACS) and is defined as a dissection of the coronary artery not associated with an atherosclerotic process, plaque rupture and/or thrombus formation and, by definition, not iatrogenic. The resulting myocardial damage is determined not by the rupture of a plaque indeed, but by the formation of an intramural hematoma (IMH) or intimal/medial disruption that determines the dissection of the arterial ...

 Open Access DOI:10.23937/iaim-2017/1710010

ST Segment Elevation Myocardial Infarction (STEMI) in the Elderly over 75 Years: Retrospective Study in a General Hospital

Abrar-Ahmad ZULFIQAR MD, MSc and Marphy KERIF MD

Article Type: Brief Report | First Published: December 31, 2018

Data on ST elevation myocardial infarction in patients aged over 75 years remains sporadic. The prognosis for ST Segment Elevation Myocardial Infarction (STEMI) patients is bleak. Mortality at one year in patients aged over 80 years is very high. We describe a series of elderly patients over 75 years treated by emergency physicians in pre-admissions or in emergency wards presenting with acute ST elevation myocardial infarction, and we compare these data with a second group of patients aged below...

 Open Access DOI:10.23937/iaim-2017/1710009

Eosinophilic Ascites, A Challenging Diagnosis

Sara Melboucy-Belkhir, Reda Khentache, Laure Andre-Ledun and Benoit Brihaye

Article Type: Case Report | First Published: November 21, 2018

Eosinophilic ascites is a rare presentation of eosinophilic gastroenteritis (EGE), a rare condition first described by Kaijser, in 1937; Hundreds of cases have been reported. EGE affects both adults and children. EGE was defined by the presence of gastrointestinal symptoms with an abnormal eosinophilic infiltrate of the intestine wall and exclusion of other causes of secondary eosinophilic infiltration; EGE has 3 clinical presentations depending on the depth of eosinophilic infiltration of the b...

 Open Access DOI:10.23937/iaim-2017/1710008

Sweet Syndrome Successfully Treated with Ruxolitinib in JAK-2 Positive Myeloproliferative Disorder

S Melboucy-Belkhir, F Brigant, R Khentache, M Bouketouche, R Garidi and B Brihaye

Article Type: Case Report | First Published: November 21, 2018

Sweet syndrome also known as acute febrile neutrophilic dermatosis includes sudden onset of painful erythematous plaques, papules or nodules, fever, histopathological finding of neutrophilic infiltrate in the dermis without leukocytoclastic vasculitis and good response to systemic corticosteroids. Sweet syndrome may be linked to various conditions: Hematologic malignancies including myeloproliferative disorders, solid cancers, medications, Crohn diseases, colitis ulcerative, and autoimmune disea...

 Open Access DOI:10.23937/iaim-2017/1710007

Practical Approach to Constrictive Pericarditis

Monik Mehta

Article Type: Short Review | First Published: October 27, 2018

Constrictive pericarditis (CP) is characterized by impaired ventricular filling secondary to a scarred pericardium. The scarred pericardium involving both parietal and visceral layers may be thickened or calcified with resultant loss of normal elasticity of the pericardial sac. The common causes include idiopathic aetiology, post cardiac surgery and systemic diseases affecting the pericardium such as tuberculosis, collagen vascular diseases, malignancy, renal diseases or radiation therapy....

 Open Access DOI:10.23937/iaim-2017/1710006

Cutaneous Angiosarcoma in a Psoriasis Patient on Infliximab and Methotrexate Therapy

Annika Silfvast-Kaiser, Amanda Abramson Lloyd and Alan Menter

Article Type: Case Report | First Published: October 12, 2018

Angiosarcoma is a soft tissue sarcoma of endothelial origin that can arise in any organ, with an incidence of up to 5% of all malignant cutaneous tumors. It is the 4th most common sarcoma of the skin and typically occurs on the scalp of white men over 60 years of age. Its prognosis is traditionally very poor, with 5-year survival rates reported as low as 11%. Risk factors for cutaneous angiosarcoma have not been clearly established. Herein, we describe a 64-year-old male with a chronic history o...

 Open Access DOI:10.23937/IAIM-2017/1710005

Clinical Outcomes of Parathyroidectomy in Resistant Renal Hyperparathyroidism

Zafer Pekkolay, Emre Aydin and Faruk Kilinc

Article Type: Research Article | First Published: September 29, 2018

Secondary hyperparathyroidism is associated with impaired calcium, phosphorus and vitamin D balance in patients with chronic renal insufficiency, and patients are often treated medically. However, some patients have medical treatment resistance. The definition of resistant renal hyperparathyroidism despite intake of calcimimetic, parathormon binding and vitamin D analogs persistent parathormon elevation and related symptoms. The only treatment for resistant renal hyperparathyroidism is surgery. ...

 Open Access DOI:10.23937/iaim-2017/1710004

A Complicated Tonsillitis: Lemierre's Syndrome

Moreno Diaz Javier, GarcĂ­a Brunen Jose Miguel, Loscos Aranda Silvia and Arenas Miquelez Aranzazu Inmaculada

Article Type: CASE REPOR | First Published: September 07, 2018

Lemierre's syndrome is a rare complication of tonsillitis, with septic emboli and jugular vein thrombosis. We present a case in a young adult without immune deficiencies that required purulent collection drainage and admission to the Intensive Care Unit. This entity, although rare, is potentially fatal and should be known for early diagnosis and treatment....

 Open Access DOI:10.23937/iaim-2017/1710003

Main Producers of World Cancer Epidemic

Robert Skopec

Article Type: Review Article | First Published: November 27, 2017

There is a growing amount of the research data confirming the cancer risk associated with cooking starchy foods at high temperatures. In a word, acrylamide is a chemical used in lots of industrial processes, including water purification, or to separation of DNA molecules in experiments....

 Open Access DOI:10.23937/iaim-2017/1710002

Sarcoidosis: The Organs Involved. A Primer for Primary Care Physicians

Richard Rissmiller and W Ennis James

Article Type: Review Article | First Published: September 18, 2017

Sarcoidosis is a granulomatous disease of unknown etiology that can affect any organ. Management of sarcoidosis patients with the potential for multi-organ involvement can be complex and require the expertise of multiple specialties. The goal of this review is to discuss clinical, imaging and epidemiologic features of organ involvement in sarcoidosis....

 Open Access DOI:10.23937/iaim-2017/1710001

Novelties on Stress Echocardiography for the Assessment of Ischemia

Jesus Peteiro and Alberto Bouzas-Mosquera

Article Type: Review Article | First Published: August 31, 2017

Stress echocardiography is an established tool for clinical assessment and decision making-process in patients with Coronary Artery Disease (CAD). Current indications include diagnosis and assessment of patients with suspected CAD and intermediate pre-test probability of the disease, assessment of patients with already known CAD, and diagnosis and assessment of patients with non diagnostic ECGs or with inconclusive exercise ECG tests....


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ClinMed Journals Index Copernicus Values

Clinical Medical Image Library: 93.51

International Journal of Critical Care and Emergency Medicine: 92.83

International Journal of Sports and Exercise Medicine: 91.84

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Ophthalmology and Clinical Research: 90.80

International Archives of Urology and Complications: 90.73

Journal of Clinical Nephrology and Renal Care: 90.33

Journal of Family Medicine and Disease Prevention: 89.99

Journal of Clinical Gastroenterology and Treatment: 89.54

Journal of Dermatology Research and Therapy: 89.34

International Journal of Clinical Cardiology: 89.24

International Journal of Radiology and Imaging Technology: 88.88

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Blood Research and Disorders: 88.22

International Journal of Diabetes and Clinical Research: 87.97

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