Adedemy JD, Agbeille MF, Agossou J, Noudamadjo A, Kpanidja G, et al. (2019) Five Years Survival Trend and Outcome among HIV Infected Children Followed Up in the Pediatric Department in a Tertiary Hospital. Int J Pediatr Res 5:052.


© 2019 Adedemy JD, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ORIGINAL ARTICLE | OPEN ACCESSDOI: 10.23937/2469-5769/1510052

Five Years Survival Trend and Outcome among HIV Infected Children Followed Up in the Pediatric Department in a Tertiary Hospital

Adedemy JD1*, Agbeille MF1, Agossou J1, Noudamadjo A1, Kpanidja G1, Aisso U1, Chabi Biaou A2, Lalya HF3, Seydou L1 and Koumakpaï-Adeothy S4

1Faculty of Medicine, Department of Mother and Child, University of Parakou, Bénin

2Regional Institute of Public Health (IRSP), Ouidah, Bénin

3Faculty of Health Sciences, Pediatric Ward, Mother and Child Department, University of Abomey Calavi, Benin

4Professeur Honoraire de Pédiatrie, Cotonou, Bénin



HIV infection still contributes significantly to high leatlity among infant and child. The aim of this work was to assess survival rate after five years of routine follow up among HIV 1-infected children in the pediatric ward of the Parakou Teaching Hospital.

Patients and methods

It was a descriptive cohort study with analytical purpose covering Five years from 2011 to 2016. It focused on 89 HIV 1-infected children. Kaplan-Meier method was used to estimate the survival probabilities. The survival trends were compared with Log-rank test. Cox regression test was used to identify factors associated with child deaths.


The HIV1-infected children had an average age of 3 years at admission. Most of children were on first line ART and most complications were malnutrition, pneumonia, pulmonary tuberculosis and oral candidosis. The probability of survival at 60 months was 0.7637. Factors associated with their deaths were the lack of children occupation (p = 0.039); 4th WHO clinical stage (p < 0.001) with 39 fold higher risk than children at WHO clinical stage 1; poor follow-up (p = 0.007) with 5.86 times fold higher risk than children with good follow up and malnutrition (p = 0.003) with 4.92 times fold higher risk than children with normal Z score.


This result will help clinicians to improve the survival rate of infected children through systematic screening at each contact with the health system, a rapid care of children at birth and regularity in children's follow-up monitoring with therapeutic education.