International Journal of Pediatric Research (IJPR) is an international peer-reviewed journal committed to promoting the best standards of scientific discoveries and scientific knowledge in the field of pediatrics. IJPR publishes articles on all the aspects related to child health. It acts a best source of information for the pediatricians, child health experts and practitioners.
International Journal of Pediatric Research is a newly launched journal which provides elaborate author benefits along with reliable copy rights policy. We are open to invite experts to join our Editorial board of IJPR. All articles published in the journal will be subjected to a stringent peer review process. It encourages authors to publish their experimental and theoretical results in as much detailed as possible.
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Open Access DOI:10.23937/2469-5769/1510075
Mada Osefori, MD, Leen Jamel Doya, MD, Bana Nezha, MD and Adnan Dayoub
Article Type: Cross Sectional Study | First Published: June 11, 2021
Transient tachypnea of the newborn (TTNB) is a common cause of respiratory distress in the postnatal period. It is rarely associated with serious complications that need intensive care. Prediction of the complications during the first hours of hospitalization is very difficult, so the purpose of the current study is to investigate the relationship between lactate dehydrogenase (LDH) level in blood and the course of Transient tachypnea of the newborn (the duration of hospitalization, and the inci...
Open Access DOI:10.23937/2469-5769/1510074
Courtney E Brennan, MD, Choo Phei Wee, MS, Jared Schiff, MD and Alan L Nager, MD, MHA
Article Type: Original Research | First Published: April 21, 2021
Medical records were retrospectively reviewed for gastroenterology patients presenting to a single, Pediatric Emergency Department with fever and a CVC from April 1, 2014 to December 31, 2016. The primary outcome measure is a positive blood culture. Additional variables studied include age, sex, history of prematurity, primary GI diagnosis, type of CVC and when it was inserted, the presence or absence of an enteral feeding tube, the use of total parenteral nutrition (TPN), weight, ED presenting ...
Open Access DOI:10.23937/2469-5769/1510073
Adam C Gamber, Ethan M Toth, Hendrik J Vreman and Tina M Slusher
Article Type: Review Article | First Published: February 19, 2021
Neonatal hyperbilirubinemia, also known as jaundice, is a significant cause of neonate death and disability in low- and middle-income countries (LMICs). Lack of adequate healthcare facilities, unreliable diagnostic- and treatment equipment, limited parental knowledge, and inconsistent- or absent treatment protocols all contribute to exceptionally high rates of morbidity and mortality especially in Sub-Saharan Africa. This review summarizes the etiology and treatment of neonatal hyperbilirubinemi...
Open Access DOI:10.23937/2469-5769/1510072
Aaradhana, Bineeta Kashyap, Krishna Singhla and Rahul Sharma
Article Type: Original Research | First Published: December 31, 2020
High sensitivity CRP (Hs-CRP) has not been studied in children with dengue so far. We conducted this descriptive cross-sectional study to compare hs-CRP levels between a group of 31 children under 12 year of age with dengue (positive NS1 antigen and/IgM ELISA for dengue) and healthy comparison group and between severe and non-severe dengue cases. Hs-CRP levels were assessed in sera of hospitalized dengue cases and healthy controls. Median (IQR) hs-CRP levels were 46.59 (34.8, 67.0) mg/L and 0.53...
Open Access DOI:10.23937/2469-5769/1510071
Ravi Patcharu, MS, MCh, Karunesh Chand, MS, MCh and Badal Parikh, MD
Article Type: Research Article | First Published: November 05, 2020
Esophageal dilatation is the modality of choice for managing anastomotic stricture after primary repair of esophageal atresia (EA). Balloon dilatation over guide wire is the preferred technique with minimal chances of mucosal erosion. In some cases of tight strictures, safe antegrade dilatation becomes impossible if the guidewire cannot be negotiated across the stricture. In such situations, retrograde dilatation is a safer alternative to avoid another thoracotomy for stricture resection and ana...
Open Access DOI:10.23937/2469-5769/1510070
Babur M Shakirov, PhD and Noila Ashurova, MD
Article Type: Research Article | First Published: October 23, 2020
Thermal inhalation injury is one of the factors aggravating the course of burn disease and resulting in patient’s death. According to literary data, damage to respiratory tract occurs approximately in 30% of cases with severe burn injury. Thermal inhalation injury severity can be determined not so much by airway burns but by toxic inhalation damage to the lungs and whole body with high toxic gaseous and vaporized chemical components of smoke. During a 3 year period 28 children with deep burns ...
Open Access DOI:10.23937/2469-5769/1510069
Rishika Das, RN Mandal, Anurag Agarwal, Sumod Kurian and Bhawna Mahajan
Article Type: Original Article | First Published: October 14, 2020
An observational cross sectional study was conducted at a tertiary care center over a period of one year (April 2017 to March 2018). Stable children with ACHD aged between 6 months to 5 years were selected as cases and age matched children without ACHD as controls. Echocardiography was done in all the patients with clinical findings of ACHD. A total of 83 children (55 cases and 28 controls) were enrolled. The severity of the ACHD was determined by the defect size and the pressure gradient across...
Open Access DOI:10.23937/2469-5769/1510068
Adriana Nieto-Sanjuanero, Arturo Alejandro García-Ramírez, Ramón Gerardo Sánchez-Cortés, Joshua Rodrigo De la O-Vega, Arturo Gerardo Garza-Alatorre and Manuel Enrique De la O-Cavazos
Article Type: Original Article | First Published: October 03, 2020
Heart diseases are considered among the most frequent congenital malformations; they have a great impact on pediatric morbidity and mortality. Children with congenital heart disease present motor and neurocognitive deficits, as well as specific functions such as attention and executive functions can be affected. It is an observational, analytical, retrospective, and cohort study, in which 10 postoperative cardiac surgery patients with the use of an extracorporeal pump were recruited regardless o...
Open Access DOI:10.23937/2469-5769/1510067
Gedif Meseret Abebe
Article Type: Review Article | First Published: August 08, 2020
Cronobacter sakazakii is an opportunistic foodborne pathogen that causes diseases like meningitis, necrotizing enterocolitis, and bacteremia in immunocompromised, low weight individuals, neonates, infants, and elders. Cronobacter sakazakii has the ability to persist in extremely dried foods such as powdered infant formula (PIF). Infant food contamination by this bacterium is attributed to biofilm which are microbial communities attached to biotic or abiotic surfaces using a self-produced matrix ...
Open Access DOI:10.23937/2469-5769/1510066
Parth Patel, Palash R Gogoi, Santanu Deb, Prasenjit Paul, Sabrina Yesmin, Lima Sangla Jamir and Pramod Paharia
Article Type: Original Research | First Published: July 16, 2020
Hypoglycemia is one of the commonest metabolic problems in contemporary neonatal medicine. In the majority of healthy neonates, the frequently observed low blood glucose concentrations are not related to any significant problem and merely reflect normal processes of metabolic adaptation to extrauterine life. However, when low blood glucose levels are prolonged or recurrent, they may result in acute systemic effects and may result in neurologic sequelae....
Open Access DOI:10.23937/2469-5769/1510065
Chaima Rherib, Fatima Jabourik and Abdelali Bentahila
Article Type: Image Article | First Published: July 15, 2020
18-months-old girl, the child of related parents, with no particular pathological history, presented with respiratory disorders associated with the fever and cough. On The clinical examination, the child was febrile and had respiratory distress. The respiratory rate was 60/ min, heart rate 100/min, and blood pressure 100/70 mmHg, The weight and height were 10 kg (under 2DS) and 70 cm (normal for that age) respectively the facies was particularly suggestive of cutis laxa: An early senile appearan...
Open Access DOI:10.23937/2469-5769/1510064
Valeria Botelho, Ingridy Caroline Ferreira Silva, Paula Braga Daltro, Indiry Caroline Ferreira Silva, Rodrigo Jorge de Souza da Fonseca, Jane Mary de Medeiros Guimarães, Gildásio Daltro
Article Type: Review Article | First Published: June 25, 2020
An electronic search for studies developed in the last 20 years in the main databases was carried out: PUBMED, SCIELO, MEDLINE and BIREME using the descriptors: Femoral head osteonecrosis, sickle cell anemia, prevalence associated with Boolean operators: or and and. Studies published in English, pediatric age range between 0 and 18 years and studies available for access, were adopted as limits. At the end, 28 scientific articles were found. After reading the title and summary, only one study fit...
Open Access DOI:10.23937/2469-5769/1510063
Khadijat Omeneke Isezuo, Ben Oloche Onankpa, Asmau Adamu, Fatima Bello Jiya, Maryam Amodu-Sanni, Bilkisu Ilah Garba, Olubusola Busayo Okwuolise and Edzu Usman Yunusa
Article Type: Original Article | First Published: June 11, 2020
Delay in seeking appropriate health care by caregivers is an important modifiable factor which contributes to childhood morbidity and mortality in developing countries. This study was carried out to assess the socio-demographic factors associated with late hospital presentation and outcome of acute febrile illnesses among children aged < 15 years in an emergency unit. Hospital based study in the Emergency Paediatric Unit of Usmanu Danfodiyo University Teaching Hospital (UDUTH), Sokoto....
Open Access DOI:10.23937/2469-5769/1510062
Ruth E Propper, PhD
Article Type: Letter to the Editor | First Published: May 29, 2020
Coronavirus disease 2019 (COVID-19), the illness caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is currently causing a global pandemic. Despite its easy transmissibility and oftentimes severe course in adults, children have been predominantly spared the worst of the disease, tending to suffer only mild illness. However, recently across multiple countries, there have been hundreds of anecdotal reports of Kawasaki, or Kawasaki-like disease, in children, potentially linked ...
Open Access DOI:10.23937/2469-5769/1510061
Adil ZEGMOUT, Hanane CHARAF, Abdelhalim BOUCAID, Youness AMCHICH, Hicham SOUHI, Hanane EL OUAZZANI, Ismail Abderrahmane RHORFI and Ahmed ABID
Article Type: Case Report | First Published: May 08, 2020
Thoracic ganglioneuromas are exceedingly rare. They arise from neural crest cells. These tumors are mostly asymptomatic, but massive tumors can present symptoms related to locoregional compression like dyspnea or scoliosis. We report a case of thoracic paravertebral giant ganglioneuroma in a 12-year-old child presenting as a large intrathoracic mass in the posterior mediastinum with intimate contact with the dorsal spine. That masse causes skeletal deformity and scoliosis. Scoliosis secondary to...
Open Access DOI:10.23937/2469-5769/1510060
Atef Alshafei, MRCPCH. MSc
Article Type: Review article | First Published: April 09, 2020
Improvement of neonatal intensive care in the modern era has greatly changed the demographic image with evolving new generation of extreme preterm survivors. And indeed, evolving new co-morbidities that influence the short and long-term outcomes of these infants. Periventricular-Intraventricular hemorrhage (PVH-IVH) is a significant health problem affecting the brain structures in a critical stage of development in preterm infants. Although the incidence has declined since the 80's of the last c...
Open Access DOI:10.23937/2469-5769/1510059
Gigi Sam, Sarah Zinaf, Maha Hamoud and Noora Inad
Article Type: Original Article | First Published: February 13, 2020
Sleep is a prime factor of healthy development and has been associated with emotional, behavioural, and cognitive development. This study investigates sleep parameters and associated sociodemographic characteristics in a population-based online method in Saudi children from infancy to four years of life. A Brief Infant Sleep Questionnaire (BISQ) for sleep assessment was made available to participants through the web link in Arabic language and were filled by the mothers. The target population we...
Open Access DOI:10.23937/2469-5769/1510058
Cristiana F Martins, Bruno Loureiro, Catarina Magalhaes, Isabel Rodrigues, Monica Costeira, Ana Maia, Augusto Ferreira, Catia Sousa and Tereza Oliva
Article Type: Case Report | First Published: February 13, 2020
An 11-year-old girl with lymphoblastic lymphoma, who presented a history of leukoencephalopathy, which mimicked stroke one week after receiving high doses of intravenous methotrexate. The patient’s symptoms completely improved within two days without sequels. Ten days after a new administration of methotrexate presented right-side hemiparesis and dysarthria. Again, with full resolution. Brain magnetic resonance scan was indispensable for diagnosis. The patient was discharged home without neuro...
Open Access DOI:10.23937/2469-5769/1510057
Debrnesh Goshiye, Girum Sebsebie and Sisay Gedamu
Article Type: Research Article | First Published: October 16, 2019
Prevention of Mother-to-Child Transmission service is expanded out in accelerated fashion throughout Ethiopia with all public hospitals and health centers. However, published studies on the services' provision in the country are generally limited. If at all, they did not comprehensively examine quality of the services. The aim of the study was to assess the quality of Prevention of Mother-to-Child Transmission service at governmental Hospitals of South Wollo Zone, Amhara Region, Ethiopia, 2018. ...
Open Access DOI:10.23937/2469-5769/1510056
Lynn Kern Koegel, PhD, Katherine M Bryan, BA, Pumpki Su, MA, Mohini Vaidya and Stephen Camarata, PhD
Article Type: Review Article | First Published: September 27, 2019
Most children diagnosed with ASD will present with late onset verbal communication, and at least one third of these children will remain minimally or completely nonverbal throughout their lifespan, speaking few or no words. Challenges with verbal language can negatively affect many areas, including socialization, academics, independent living and employment. The objective of this paper was to systematically review interventions for the treatment of nonverbal and minimally verbal individuals with...
Open Access DOI:10.23937/2469-5769/1510055
Padmini Selvaganesan, Michala Dauterman, Ajay Mahajan and Jyoti Krishna
Article Type: Research Article | First Published: September 16, 2019
For diagnosing sleep apnea, patients are required to stay overnight in a sleep lab, and various physiological signals are recorded using different sensors. The data collected during the study is often prone to artifacts due to various reasons and one such artifact in younger patients is due to the use of pacifiers which corrupts the signal from the sensors. One of the sensor signals which is corrupted frequently is the airflow signal. This airflow signal is obtained using a thermistor that is pl...
Open Access DOI:10.23937/2469-5769/1510054
Rodrigo Hipolito Cifuentes, Rene Carmona Barba, Antonio Vega Valdes and Placido Espinosa Rosas
Article Type: Research Article | First Published: July 18, 2019
One female patient, on chronic acid-suppressive therapy who underwent successful laparoscopic implantation of the LES stimulation system, surgery time 1 hour, trans surgical endoscopy with absence of perforation, closure of pillars; measured by GERD daily symptom diaries the patient symptoms improved soon. Two weeks after the surgery, the patient reported better symptom control without the intake of PPI, and the absence of heartburn and regurgitation. One month follow-up with esophageal ph shows...
Open Access DOI:10.23937/2469-5769/1510053
Bishnu Prasad Mandal, Yao Yang and Jingyi Fan
Article Type: Research Article | First Published: April 24, 2019
Neurodevelopmental disorders (NDDs) are growing worldwide in both developed and developing countries. Parents are primary caregivers to recognize the signs and symptoms of children's behavior or mental -illness. This study is to obtain basic knowledge and awareness about NDDs in children in Nepali community. People in Nepali community have various religions and outdated belief. This study analyzes misconceptions and factors that influence the knowledge regarding NDDs among general populations, w...
Open Access DOI:10.23937/2469-5769/1510052
Adedemy JD, Agbeille MF, Agossou J, Noudamadjo A, Kpanidja G, Aisso U, Chabi Biaou A, Lalya HF, Seydou L and Koumakpaï-Adeothy S
Article Type: Original Article | First Published: April 08, 2019
HIV infection still contributes significantly to high leatlity among infant and child. The aim of this work was to assess survival rate after five years of routine follow up among HIV 1-infected children in the pediatric ward of the Parakou Teaching Hospital. It was a descriptive cohort study with analytical purpose covering Five years from 2011 to 2016. It focused on 89 HIV 1-infected children. Kaplan-Meier method was used to estimate the survival probabilities. The survival trends were compare...
Open Access DOI:10.23937/2469-5769/1510051
Melike METE, Gonca KESKINDEMIRCI and Gulbin GOKCAY
Article Type: ORIGINAL ARTICLE | First Published: March 06, 2019
The study was conducted in İstanbul University İstanbul Medical Faculty Social Pediatric Outpatient Clinic. Children aged 18-30 months who used BW for 30 minutes or more a day for at least 1 month constituted the user group (n = 100) and those who never used a BW were in the control group (n = 100). Information was obtained through the personal health record of the unit and by a face-to-face questionnaire applied to the families during their visits to the unit. The Ankara Development Screening...
Open Access DOI:10.23937/2469-5769/1510050
Jane M DeLuca, PhD, RN, CPNP-PC, Sara M Sarasua, PhD, MSPH and Luigi Boccuto, MD
Article Type: ORIGINAL RESEARCH | First Published: February 23, 2019
Currently, a clinical diagnosis of autism spectrum disorder (ASD) is determined by behavioral/ observational evaluations performed on children ages 2-5 years. Research suggests that laboratory-based tests for screening or diagnosis of ASD may be available in the future. In this study, we examined attitudes towards the acceptance of a hypothetical laboratory-based screening test for children for ASD. For this study, a survey was developed to capture opinions about a hypothetical ASD laboratory te...
Open Access DOI:10.23937/2469-5769/1510049
Julie Lerwick, PhD, LPC, NCC, RPT
Article Type: Review Article | First Published: February 06, 2019
In the United States pediatric hospitals and healthcare organizations are becoming more familiar with the value of Child Life Specialists to partner with children and their families to offer information, preparation, and stress reduction interventions to ease the potential negative emotional impact of a healthcare experience. To that end, Child Life Specialists have a unique role, which is not often understood by other healthcare providers. Historically casually regarded as "the hospital play la...
Open Access DOI:10.23937/2469-5769/1510047
Article Type: Case Report | First Published: December 01, 2018
D-penicillamine (D-PA) was first recognized as a potential benefit for neonatal hyperbilirubinemia (NHBI) caused by hemolytic diseases of the newborn infant or immaturity of UDP-glucuronyltransferase enzyme. During a long-term follow up study there was a remarkedly low incidence of retrolental fibroplasia (RLF) in the infants treated with D-PA in their neonatal period. Then, all infants < 1500 g birthweight were treated with D-PA to prevent retinopathy of prematurity (ROP). This preventive inter...
Open Access DOI:10.23937/2469-5769/1510046
Clemens Drenowatz and Klaus Greier
Article Type: Research Article | First Published: November 19, 2018
Dietary intake plays an important role in the development and health of children and adolescents. Puberty is a particularly vulnerable period due to the increased nutrient demands associated with growth. This age range has also been associated with various changes in health behavior. While several studies have examined the influence of the social and built environment on dietary habits during adolescence, there remains limited research on the association between biological maturation and eating ...
Open Access DOI:10.23937/2469-5769/1510045
Ping Yuan and Min Zhong
Article Type: Case Report | First Published: November 16, 2018
Acute necrotizing encephalopathy (ANE) is a rare clinical-imaging syndrome with unknown etiology, characterized by acute fulminant severe encephalopathy and brain damage with multifocal symmetry. ANE has no specific clinical symptoms and signs, similar to common encephalitis or encephalopathy symptoms. The characteristic brain imaging examination is diagnostically significant. To date, no specific treatment for ANE is available and the prognosis is poor. Here, we reported a typical case of ANE i...
Open Access DOI:10.23937/2469-5769/1510044
Reindolf Anokye, Rita Amihere, Patience Abbiaw, Enoch Acheampong, Naomi Gyamfi and Amy Budu-Ainooson
Article Type: Original Article | First Published: November 15, 2018
Most childhood ailments often present with fever which account for the most common reasons why parents seek medical care for their children; particularly, the under-five children. The study aimed to assess the mothers' knowledge of fever in their under-five children and how this is managed at home. This was a descriptive designed study that used a simple random sampling technique to select 100 participants who were mothers of under-five children who presented to the Kwahu Government Hospital, At...
Open Access DOI:10.23937/2469-5769/1510043
Christopher J Butler and Andrew Mallick
Article Type: Case Report | First Published: November 02, 2018
Migraine is a common pediatric disorder presenting with unilateral frontal headache. Hemiplegic migraine is a rare and clinically challenging subtype of migraine with aura. There are two different subtypes of hemiplegic migraines; they can occur as either sporadic or familial forms. Recently our understanding of the genetics underlying hemiplegic migraine has rapidly evolved. Familial hemiplegic migraine has been associated with pathogenic mutations in three independent genes. Migraine is a comm...
Open Access DOI:10.23937/2469-5769/1510042
Issa Al Salmi and Suad Hannawi
Article Type: Research Article | First Published: October 31, 2018
Non-communicable diseases (NCD) are rising throughout the globe over the last few decades. Developing countries bear the worse burden of these NCD. Similarly, low birthweight is increasing around the world where most of this prevalence commonly seen in the developing countries but as well in the well-developed countries where advancement of health care managed to increase the survival of the very low birthweight babies. In recent years, there has been great interest in the early development of t...
Open Access DOI:10.23937/2469-5769/1510041
Manoj D, Vinayaka HS and Basavaraj GV
Article Type: Case Report | First Published: October 24, 2018
Hemophagocytic Lymphohistiocytosis (HLH) describes a clinical syndrome of hyperinflammation resulting in uncontrolled and ineffective immune response. It may be primary or secondary HLH. Primary HLH is better defined as "genetic" encompassing both the familial hemophagocytic lymphohistiocytosis (FHL) and also HLH occurring in association with Chediak-Higashi syndrome, Griscelli syndrome type 2 and X-linked lymphoproliferative disorder. FHL is inherited as an autosomal recessive manner. The incid...
Open Access DOI:10.23937/2469-5769/1510040
Mustafa Yasar Ozdamar
Article Type: Original Research | First Published: October 19, 2018
Obliteration of the processus vaginalis during the fetal growth begins with a transient decrease in sympathetic tonus and then ends with smooth muscle cells (SMCs) undergoing apoptosis. Otherwise, an inguinal hernia (IH) occurs due to the defective obliteration. Although the mechanism in the formation of an inguinal hernia has been elucidated by many investigations, it has not been investigated whether proliferation in the IH sac cells which would lead to the benign or malignant process. In this...
Open Access DOI:10.23937/2469-5769/1510039
Sameer Sarswat, Mithilesh Kumar and Raju Gupta
Article Type: Original Article | First Published: October 05, 2018
Typhoid fever is a life-threatening systemic infection occurring in developing countries like India. The presenting signs and symptoms of typhoid fever in children differ from adults. Some studies indicate reemergence of sensitivity of Salmonella with chloramphenicol. 164 children between 1-12 years of age with suspected enteric fever were enrolled in the study. Out of these, 73 patients were diagnosed as enteric fever and clinical features were compared among different age groups. Antibiotic se...
Open Access DOI:10.23937/2469-5769/1510038
Mohd Ibrahim Wani, Mudasir Nazir, Roumissa Lone, Mohd Rafiq, Syed Wajid Ali and Bashir Ahmad Charoo
Article Type: Research Article | First Published: October 05, 2018
Almost 60% of normal healthy term babies and 80% of preterm babies develop visible jaundice in the first week of life. Although the outcome of the majority is benign, newborns with untreated severe hyperbilirubinemia can develop short and long-term sequelae of bilirubin encephalopathy. This study was designed to evaluate the impact of exchange transfusion on various biochemical parameters and to assess the need for routine calcium gluconate supplementation during the procedure....
Open Access DOI:10.23937/2469-5769/1510037
Nurah M Hammoud, Harold W de Valk, Lenie van Rossem, Geertje W Dalmeijer, Douwe H Biesma, Jan M Wit, Maarten Rijpert and Gerard HA Visser
Article Type: Research Article | First Published: October 05, 2018
Offspring from women with diabetes have an increased risk for childhood obesity, which may be related to the abnormal intrauterine environment, genetic imprinting or current diet and lifestyle. We analyzed whether diet and lifestyle differ between offspring from women with either type 1, type 2 or gestational diabetes. We collected completed questionnaires from parents of 51 offspring from women with type 1 diabetes (ODM1), 21 of women with type 2 diabetes (ODM2) and 87 of women with gestational...
Open Access DOI:10.23937/2469-5769/1510036
Oloyede Iso Precious and Okpokowuruk Frances Sam
Article Type: RESEARCH ARTICLE | First Published: September 12, 2018
Sucking of the digits is the most common oral habit found in children. It is a form of non-nutritive sucking which appears to be influenced by various factors. When the habit becomes prolonged, it can lead to both dental and hand complications. Breastfeeding is one of the factors known to be protective against this habit in children. Therefore, the aim of this study was to find out the prevalence of digital sucking in our environment and the influence of breastfeeding/exclusive breast feeding in...
Open Access DOI:10.23937/2469-5769/1510035
Aaradhana Singh and Ravi Sachan
Article Type: Case Report | First Published: July 12, 2018
Congenital Cytomegalovirus infection (CMV) has varied presentations ranging from asymptomatic to involvement of multiple organ systems like central nervous system, gastrointestinal, hepatic and hematopoietic. Jaundice is a manifestation of congenital CMV presenting as neonatal hepatitis or cholestasis jaundice. We report a case of severe conjugated hyperbilirubinemia presenting on the first day of life that was diagnosed as a case congenital CMV on further workup....
Open Access DOI:10.23937/2469-5769/1510034
Livia Roberta Piedade De Oliveira, Ivete Pomarico Ribeiro De Souza and Carla Martins
Article Type: Case Report | First Published: June 22, 2018
Merosine Deficient Congenital Muscular Dystrophy (MDCMN) is a rare subtype of Muscular Dystrophy and it is defined as generalized hypotonic muscular syndrome. This case report aimed to describe the oral status of a six-year-old girl with MDCMN. The family's and child's chief complaint was bad breath. The child, who presented normal intelligence, had physical disability with mobility impairment and so, used wheelchair....
Open Access DOI:10.23937/2469-5769/1510033
Angel J Lacerda Gallardo, Daysi Abreu Perez, Miguel Mazorra Pazos, Gustavo P Valdivieso Caraguay, Gustavo M Obregon Criales and Paschal Edes Songoro
Article Type: Research Article | First Published: June 11, 2018
To evaluate in a general way the usefulness of early decompressive craniectomy in pediatric patients with severe traumatic brain injury, the time elapsed from the moment of trauma to the arrival at the neurotrauma center, Glasgow coma scale on admission and its possible association with discharge results and evaluate the results of the computerized tomography images on admission and sequential, as well as the behavior of intracranial pressure and cerebral perfusion pressure....
Open Access DOI:10.23937/2469-5769/1510032
Asli Derya Kardelen, Ismail Yildiz, Beyhan Omer and Fatma Oguz
Article Type: Research Article | First Published: May 30, 2018
Vitamin D has an important role in many parts of the body, it maintains serum calcium (Ca) and phosphorus (P) homeostasis and is necessary for the health of bones and muscles. It also has positive effects on the immune system. It has a protective effect against hypertension, cardiac disease, various cancers, type 1 diabetes, autoimmune and allergic diseases....
Open Access DOI:10.23937/2469-5769/1510031
Kushnareva МV, Markhulia Kh М, Keshishyan ES and Semenov AV
Article Type: Research Article | First Published: March 19, 2018
Severe pneumonia had 10 infants, moderate stage was among 4 infants, an acute stage was observed in 12 patients, and prolonged stage was in 2 infants. Severe form of the disease was presented by pronounced symptoms of infectious toxicosis, respiratory and cardiovascular insufficiency, physical changes from the lungs. Bronchopulmonary dysplasia was developed in two infants....
Open Access DOI:10.23937/2469-5769/1510030
Costanza Tognon, Luisa Meneghini, Francesco Fascetti Leon and Piergiorgio Gamba
Article Type: Original Article | First Published: February 17, 2018
Since many years, feasibility and safety of thoracoscopic surgery in infants with pulmonary malformations has been confirmed. Nevertheless, infants present some problems caused by the anatomical and physiological peculiarities typical of the age and of the size of the structures. Several ways to overcome these difficulties have been proposed to assure efficacy and safety of mono-pulmonary ventilation. The knowledge of the infant's respiratory physiology is essential to prevent complications and ...
Open Access DOI:10.23937/2469-5769/1510029
Aravindhan Veerapandiyan, Lama Charafeddine, Durriyah Sinno and Mohamad A Mikati
Article Type: Research Article | First Published: January 31, 2018
Early Childhood Developmental Interventions (ECDIs) were developed with the aim of improving overall functional outcome of children over and above what the home environment provides. Cost-Benefit Analysis (CBA) of ECDIs using a flexible and easy to apply model that can complement the more granular and highly desirable CBA studies that often may be too difficult or too expensive to perform....
Open Access DOI:10.23937/2469-5769/1510028
Tejas N Doctor, Efrant Harnaen, Bob Seith, Kenneth Tan and Simon Craig
Article Type: Original Article | First Published: December 04, 2017
Extremely preterm infants, < 28 week of gestational age, (ELGANs) continue to need high levels of health-care post-discharge from the NICU. We studied post-NICU hospital contacts of this highly vulnerable population and present data from infants treated in our health network....
Open Access DOI:10.23937/2469-5769/1510027
Carme Alejandre, David Vila, David Vila, Sergio Benito, Patricia Corniero, Monica Balaguer, Susana Segura, Francisco Jose Cambra and Iolanda Jordan
Article Type: Research Article | First Published: December 01, 2017
Critically ill children who are admitted to Pediatric Intensive Care Unit (PICU) often receive analgesia and sedation for pain, comfort and safety. Moreover the new objectives of sedation include maintenance of the functioning of the neuromuscular system early upon ventilatory support....
Open Access DOI:10.23937/2469-5769/1510026
Hui Li, Huiping Zhang, Qian Su, Dan yao, Shuya Shao, Ding Ding, Shaoli Wang and Zhongliang zhu
Article Type: Research Article | First Published: March 17, 2017
Disorders in the expression of plasma homocysteine are significantly related to psychological stress. There is also evidence that prenatal maternal psychological stress could lead to adverse birth outcomes. The present study aimed to determine whether disorders in the expression of plasma homocysteine would be associated with the adverse birth outcomes following prenatal psychological stress (PPS)....
Open Access DOI:10.23937/2469-5769/1510025
Freek Hollman, Pascal Vroemen, Lodewijk Van Rhijn, Dam Surtel, A Cremers, Paul Rompa, Prosper Moh and Heleen Staal
Article Type: Original Article | First Published: November 05, 2016
This study will present the histological findings of biopsies acquired from the medial and lateral part of the proximal tibia during the W/M serrated osteotomy in patients with infantile Blount's disease. It is hypothesized that the medial metaphyseal area of the proximal tibia will present a different ossification pattern compared with the lateral area....
Open Access DOI:10.23937/2469-5769/1510024
Atul Malhotra, Michael C Fahey, Suzanne L Miller, Graham Jenkin, JV Singh, Pawankumar Patil, Vishwajeet Kumar and Euan M Wallace
Article Type: Research Article | First Published: August 24, 2016
Background: Birth asphyxia is a major cause of neonatal deaths in the developing world. The management of an asphyxiated infant includes effective resuscitation at birth and treatment of subsequent hypoxic ischemic encephalopathy (HIE). HIE is frequently under recognized in this setting and this contributes to early infant mortality and morbidity. Methods: We present the evolution of a HIE recognition training program for rural India. The development of this program involved close community int...
Open Access DOI:10.23937/2469-5769/1510023
Seyma Kayal, Ilker Ertugrul, Vehbi Dogan, Senem Ozgur, Utku Arman Orun and Selmin Karademir
Article Type: Original Article | First Published: August 22, 2016
A total of 132 patients who underwent TEEPS at our institution were included. Demographic features and symptoms of patients were evaluated and the patients were divided into three groups to compare the inducibility of tachycardia: Symptom group was consisting of 91 patients who had symptoms of arrhythmias, Wolf Parkinson White group was consisting of 18 patients who had Wolf Parkinson White pattern on surface electrocardiogram, and Tachycardia group was consisting of 23 patients who had previous...
Open Access DOI:10.23937/2469-5769/1510022
Yurieva Eleonora Alexandrovna, Vozdvizhenskaya Ekaterina Sergeevna, Kushnareva Maria Vasilievna and Novikova Natalia Nicolaevna
Article Type: Review Article | First Published: August 19, 2016
The following information about the endogenous intoxication in children (from 2 up to 17 y.o.) with nephrological diseases was presented. Endogenous intoxication as multisystemic pathological condition occurs as the result of action on the organism of toxic substances of endogenous or exogenous origin. It is characterized by the following: a) violation of the barrier function of the organism against toxins, b) violation of transport mechanisms of toxic substances to the organs of their transform...
Open Access DOI:10.23937/2469-5769/1510021
Houda Boudiaf, Manel Gherbi and Moussa Achir
Article Type: Case Report | First Published: July 22, 2016
The patient is a 5-year-old male with findings suggestive of Kawasaki disease. He was treated with intravenous gamma globulin (IVG) and oral aspirin. Because the fever persisted, he received additional IVG and intravenous methylprednisolone. Echocardiography showed diffuse dilatation of the right coronary artery (RCA; 13 mm) and proximal dilatation of the left main coronary artery (LMCA; 8 mm)....
Open Access DOI:10.23937/2469-5769/1510020
Luis Miguel Borrego, Magna Correia, Ines Mota and Mario Morais-Almeida
Article Type: Case Report | First Published: June 07, 2016
Over-the-counter medicines are available without prescription, allowing for convenience and facilitating self-care. We report a case of an adverse reaction to a pharmaceutical formula for gingival eruption in a child with milk allergy. The objective of this report is to alert health-care professionals regarding the potential threat of over-the-counter formulations to children with food allergy. Over-the-counter (OTC) medicines are available without prescription. As the number of OTC drugs rise, ...
Open Access DOI:10.23937/2469-5769/1510019
Jillian S Owens, Michele Strom, Farsad Farassati, Krista Van Roestel, Kathryn Chambers, Penni Kean, Megan Carricato, Vicky L Ng, Yaron Avitzur and Glenda Courtney Martin
Article Type: Research Article | First Published: May 24, 2016
Minimal research has been conducted on the effect of nutritional status on acute post-transplant outcomes in pediatric liver transplant patients. The purpose of this study was to determine the effect of pre-transplant nutritional status (height, weight, albumin, hemoglobin, Vitamin A, Vitamin E, Vitamin D, mean corpuscular volume (MCV), calcium, magnesium and phosphorus) on acute post-transplant outcomes (length of hospital stay and infection rate)....
Open Access DOI:10.23937/2469-5769/1510018
Rowena Ng, Jennifer Tang and Maria Kroupina
Article Type: Short Communication | First Published: May 16, 2016
Internationally adopted (IA) children are at a greater risk for emotional, behavioral and adaptation difficulties, relative to typically-developing youth due to the fact that many of them experience severe social-emotional deprivation and other adverse experiences preadoption. Importantly, a disproportionate number of IA children show insecure attachment with caregivers even post-adoption, which has been associated with later problems with affect and behavioral regulation. Notably, research has ...
Open Access DOI:10.23937/2469-5769/1510017
M. Kirchner, B. Robinson, L. Strothmann, A. Sonnenschein and W. Mannhardt-Laakmann
Article Type: Research Article | First Published: March 28, 2016
The oligoarticular juvenile idiopathic arthritis (oJIA) refers to a heterogeneous group of chronic inflammatory joint diseases of childhood and adolescence of unknown aetiology. The oligoarticular subtype is described as a T helper cell-mediated inflammatory disorder, mainly due the large number of activated Th1 cells and the abundance of pro-inflammatory cytokines in the inflamed joint....
Open Access DOI:10.23937/2469-5769/1510016
Aditi Mathur, Anmol Mathur and Vikram Pal Aggarwal
Article Type: Original Article | First Published: March 26, 2016
The dental treatment is still a night mare for most of the people. Dental neglect have tight bond with dental caries. Dental caries has been called as scourge of modern civilization and is without doubt, one of the mankind's most prevalent chronic diseases. The concept of dental neglect may offer a viable linkage between dental health and the cultural, social and attitudinal factors. Australia's 1993 children's protection act defines neglect as "any serious omission or commission by a person whi...
Open Access DOI:10.23937/2469-5769/1510015
Maria Isabel Roldos and Vanessa Bustamante
Article Type: Case Study | First Published: March 18, 2016
Health care utilization databases rely on the vested commitment of patients and their families, but mainly from medical care personnel to provide information of diagnoses, procedures, and follow-up visits. Most developed countries produce health care utilization data from hospital and physician sources through large studies funded by federal research monies. In developing countries, these databases are scare....
Open Access DOI:10.23937/2469-5769/1510014
Joanne S. Katz and Agnes Perenyi
Article Type: Original Research Article | First Published: January 15, 2016
Due to the recent advances in obstetrical and neonatal intensive care, an increasing number of preterm infants survive. The surviving infants have high risk for often multiple morbidities, repeated hospitalizations after discharge and adverse neurodevelopmental (ND) outcomes. Several studies suggest improvement in early neurodevelopment in some of the subgroups of preterm infants. Other authors report no improvement or unchanged ND outcomes, especially in very preterm infants....
Open Access DOI:10.23937/2469-5769/1510013
Lukas Schroder, Mark Born, Marcus Panning, Anna Maria Eis-Hubinger, Andreas Muller, Rainer Ganschow and Ingo Franke
Article Type: Original Article | First Published: December 31, 2015
The A(H1N1)pdm09 virus is a major pathogen causing acute respiratory diseases (ARD) in children worldwide, leading to high rates of ambulatory consultations and hospitalizations. The seasonal influenza of 2012/2013 in Germany was unusually severe, leading to higher numbers of hospitalization rates as compared with previous seasons. This trend was even notable in our tertiary care Children's Hospital at the University of Bonn, Germany....
Open Access DOI:10.23937/2469-5769/1510012
Hamdi Kaziz, Thabet Mouelhi, Walid Osman, Mohamed Amine Triki, Nader Naouar and Mohamed Laziz Ben Ayeche
Article Type: Case Report | First Published: December 26, 2015
Subacute osteomyelitis is a rare affection. Clinical presentation is often unclear and can lead to a delay in diagnosis. As a matter of fact, subactue metacarpal osteomyelitis is usually missed at the first time, so that some complications may occur like brachymetacarpia or loss of motion. We report a 10 year-old boy, with a subacute metaphyseal osteomyelitis of the second right metacarpal bone. The radiological features can mimic various benign or malignant bone tumours and non-pyogenic infecti...
Open Access DOI:10.23937/2469-5769/1510011
Maria Luisa Martin-Ruiz, Miguel Angel Valero, Maria Linden, Susana Nunez-Nagy and Angeles Gutierrez Garcia
Article Type: Short Communication | First Published: November 11, 2015
The creation of adequate smart monitoring solutions at home can provide professionals with reliable information about the health status of a child. Furthermore, toys and playing are crucial for the overall development of a human being. Hence, the aim of this research is to improve the exactitude of traditional evaluation methods by embedding sensors into daily life toys that provide professionals with added value supplementary evidence enhanced by Decision Support Systems (DSS). It will be possi...
Open Access DOI:10.23937/2469-5769/1510010
Efrant Harnaen, Tejas N Doctor and Atul Malhotra
Article Type: Case Series | First Published: October 19, 2015
It is a rare cause of neonatal blood stream infections in developed countries and most studies report its occurrence in the setting of an outbreak. We present data from a busy tertiary neonatal intensive care unit in Australia, over a 12-year period. During the study period, we found 6 cases of P. aeruginosa blood stream infection (0.5% of total positive blood culture episodes and 4.2% of total gram-negative culture episodes)....
Open Access DOI:10.23937/2469-5769/1510009
E J van der Gaag, N Bolk-van Droffelaar, J van der Palen and R Baarsma
Article Type: Research Article | First Published: October 13, 2015
In developed countries, dietary intake of pre-schoolers is sometimes inadequate. Not because of insufficient provisions, but due to picky eating and behavioural feeding problems. Micronutrient deficiency could be a result, but is most of the time difficult to detect due to failing laboratory evaluations. Iron deficiency is the most common detected nutritional deficiency in children; other deficiencies may be present but are also hidden because they cannot always be found in routine evaluations. ...
Open Access DOI:10.23937/2469-5769/1510008
Joel Navarrete Espinosa, MC Beatriz Rivas Sanchez and Dra. Maria Luisa Soriano Rodriguez
Article Type: Research Article | First Published: October 12, 2015
Cross-sectional study in school children 8-12 years of age; Leptospira identification tests (IFI and Dark Field: Microbiology and Parasitology Department, FM-UNAM) were performed and risk factors were researched. Those positive to IFI (cutoff 1: 80) and dark field in blood and urine were considered positives. Prevalence, prevalence ratios, and multivariate analysis were estimated....
Open Access DOI:10.23937/2469-5769/1510007
Lindsey N Zimmerman and Amy J Wagner
Article Type: Case Report | First Published: October 10, 2015
Hair tourniquets are uncommon occurrences in children that can have devastating consequences. They tend to be found on fingers and toes, but have also been reported to involve the genitalia. We present a case of a hair tourniquet involving the clitoris of a child. A high index of suspicion is necessary in order to facilitate early diagnosis and treatment....
Open Access DOI:10.23937/2469-5769/1510006
Mehmet Sinan Dogan, Izzet Yavuz, Osman Atas, Abdullah Emre Karaali, Fatih Demirci and Abdulsamet Tanik
Article Type: Case Series | First Published: October 09, 2015
Tooth injuries constitute an integral part of clinical dentistry. Complicated crown fracture and crown-root fracture are the most common injury in the permanent dentition. The success of treatment and prognosis of the traumatized tooth depends on accurate diagnosis and treatment procedures and materials....
Open Access DOI:10.23937/2469-5769/1510005
Sampson Antwi, Anima Sarfo, Abigail Amoah, Anna Serwaa Appia and Esther Obeng
Article Type: Research Article | First Published: September 14, 2015
Acute kidney injury (AKI) is a relatively common condition encountered in everyday paediatric practice. It remains a significant contributor to preventable deaths especially in resource constraint regions of the world largely due to lack of dialysis services. This 3-year data analysis (2010-2012) was undertaken to determine the aetiology and treatment/mortality outcomes of children with AKI presenting to a Teaching Hospital in Ghana. AKI was defined in this analysis by the RIFLE and KDIGO cri...
Open Access DOI:10.23937/2469-5769/1510004
Krzysztof Orczyk, Joanna Swidrowska, Jerzy Stanczyk and Elzbieta Smolewska
Article Type: Research Article | First Published: April 08, 2015
Juvenile dermatomyositis (JDM) is the most common inflammatory myopathy in children. Diagnostic criteria by Bohan & Peter are originally formulated for adults. A wide range of differences in clinical course of dermatomyositis between adults and children has provoked to set a new look at the existing criteria....
Open Access DOI:10.23937/2469-5769/1510003
Yu-Shu Huang, Stacey Quo, J Andrew Berkowski and Christian Guilleminault
Article Type: Research Article | First Published: April 08, 2015
A retrospective study of prepubertal children referred for suspicion of obstructive sleep apnea, found 27 subjects with non-syndromic short lingual frenulum. The children had findings associated with enlarged adenotonsils and/or orofacial growth changes....
Open Access DOI:10.23937/2469-5769/1510002
Maria Cristina Azcona-Sanjulian, Ana Catalan Lamban and Borja Lana Ruiz
Article Type: Original Article | First Published: March 13, 2015
Objective: To assess the effect of metformin on weight, BMI, body fat, and insulin sensitivity in obese children and adolescents. Methodology: The study was prospective, and included 21 patients with obesity (8 male, 13 female) with a mean age of 12.31 (3.87) years. Inclusion criteria were a fat mass percentage (FM%) of over 25% in males and over 30% in females, a BMI of greater than the 95th percentile, and a lack of response to nutritional and lifestyle changes over three months....
Open Access DOI:10.23937/2469-5769/1510001
Yasunobu Hayabuchi, Miho Sakata and Shoji Kagami
Article Type: Review Article | First Published: February 20, 2015
Multidetector-row computed tomography (MDCT) scanners are a widely available, accurate, and noninvasive technique for the diagnosis of pediatric cardiovascular disorders. A lots of articles published regarding the usefulness of MDCT mostly describe that it can be an alternative to the invasive catheterization and angiography. The unique diagnostic features of this imaging modality have been largely ignored or disregarded. We presented the pathological conditions that cannot be diagnosed by conve...
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