FERNANDEZ L, SEIJAS R, PÉREZ-BELLMUNT A, RAGAZZI P, PEILLON O, et al. (2019) Anterior Cruciate Ligament Reconstruction with Platelet Rich Plasma: Systematic Review. Int J Sports Exerc Med 5:142.


© 2019 FERNANDEZ L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

RESEARCH ARTICLE | OPEN ACCESS DOI: 10.23937/2469-5718/1510142

Anterior Cruciate Ligament Reconstruction with Platelet Rich Plasma: Systematic Review

Laura FERNANDEZ1, Roberto SEIJAS1-3, Albert PÉREZ-BELLMUNT1*, Paolo RAGAZZI1, Olivier PEILLON1 and Pedro ALVAREZ1-4

1Anatomy Unit, International University of Catalonia, Spain

2Fundación García-Cugat, Spain

3GC Arthroscopy, Chiron Hospital, Spain

4Catalan Mutualidad de Futbolistas, Spanish Football Federation, Spain



The aim of this study was reviewed the scientific evidence of the relationship that could exist between the use of Platelet Rich Plasma (PRP) after the reconstruction of the Anterior Cruciate Ligament (ACL).


We performed a systematic using the following key words: platelet rich plasma AND anterior cruciate ligament. Abstracts were screened by a single reviewer. For those studies meeting the eligibility criteria, full-text articles were obtained.


From 127 studies found only 5 articles were included in this systematic review. We found the presence of inflammatory diseases, DM, advanced osteoarthrosis (grade III-IV), previous knee surgeries, malignant diseases, contrast allergy, renal disease and thrombocytopenia.


The use of the platelet rich plasma after the ACL reconstruction with patellar tendon, demonstrates a better autograft recovery in terms of vascularization, bone remodeling and edema decreasing, achieving an earlier autograft homogenization.