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© 2018 Liang J, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

CASE REPORT | OPEN ACCESS DOI: 10.23937/2474-3658/1510060

Tigecycline Induced Cholestatic Liver Injury: A Case Report

Jing Liang1, Kai Zhao2, Liqin Zhu2* and Yihe Liu2

1Tianjin HuangHe Hospital, China

2Tianjin First Central Hospital, China


A 41-year-old female patient received tigecycline because of abdominal infection caused by carbapenem-resistant klebsiella pneumoniae (CRKP) after performing cholangiolithotomy by the endoscopic retrograde cholangio-pancreatography (ERCP). Subsequently she developed cholestatic liver injury as substantiated by increased alkaline phosphatase (ALP) and bilirubin. Tigecycline was switched to dual carbapenems. Her liver function tests improved. We suggest that bilirubin levels should be cared in patients with tigecycline in order to avoid severe cholestatic liver injury.