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Review Article Open Access

Innovative Treatment in Menopause: Tissue-Selective Estrogen Complex (TSEC)

Baquedano L, Sanchez Borrego R, Abad P, Jurado AR, Manubens M and Mendoza N
Reprod Med Int Volume 1, Issue 1

Abstract: Menopause is not a disease, therefore it is not always necessary to treat women in the transition and in menopause. However, hormonal changes can be associated with symptoms, the most common are hot flashes and night sweats. Others like dyspareunia, vaginal dryness, mood swings and sexual disfunction can frequently appear. In addition, there is an increase in bone resorption on ocassions leading to osteopenia and osteoporosis. Women who are severely symptomatic, 25-30% more or less of all menopause women, have their quality of life affected.

PDF   Full Text   DOI: 10.23937/rmi-2017/1710004

Short Communication Open Access

Hyperhomocysteinemia and Polycystic Ovary Syndrome

Mohamed Nabih EL-Gharib
Reprod Med Int Volume 1, Issue 1

Abstract: Homocysteine (Hcy) is an essential amino acid required for the growth of cells and tissues. Homocysteine (Hcy) is an intermediate product formed by the breakdown of methionine the aid of certain B-vitamins. Homocysteine remethylation to methionine is dependant on both folate and cobalamin (Figure 1) and may undergo transsulfuration to cysteine and cystathionine.

PDF   Full Text   DOI: 10.23937/rmi-2017/1710003

Mini Review Open Access

Does Luteal Phase Deficiency Exist and What is its Association with Infertility?

Monica S Chung, Laurice Bou Nemer and Bruce R Carr
Reprod Med Int Volume 1, Issue 1

Abstract: Luteal Phase Deficiency (LPD), also known as luteal phase defect, is a concept that was defined by Georgeanna Seegar Jones in 1949 as reduced progesterone production by the Corpus Luteum (CL). LPD results from low endogenous progesterone production and the resultant insufficiency to maintain a secretory endometrium to allow embryo implantation and growth.

PDF   Full Text   DOI: 10.23937/rmi-2017/1710002

Case Report Open Access

Inadvertent Use of Depot GnRH-agonist Trigger and its Effect on the Luteal Phase: A Case Report

Shahar Kol and Ofer Fainaru
Reprod Med Int Volume 1, Issue 1

Abstract: The use of short acting GnRH agonist to trigger final oocyte maturation in IVF is a common practice. Its primary advantage is prevention of significant ovarian hyperstimulation syndrome. The effect of a long acting GnRH agonist preparation in that setting is not known. In the current case report, a depot preparation was given accidentally, resulting in prolonged and robust luteal phase activity, with luteolysis achieved only 14 days after administration.

PDF   Full Text   DOI: 10.23937/rmi-2017/1710001

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