International Archives of

Clinical Physiology

Early Online

 Open Access DOI:10.23937/iacph-2017/1710004

On the Neurophysiology of Delusional Disorders: Top-Bottom vs. Bottom-Up Theories

Gentian Vyshka and Jera Kruja

Article Type: Opinion Paper | First Published: October 14, 2019

The psychopathology of delusions has been indelibly denoted from top-bottom theories, with a very long psychiatric tradition explaining the issue as a cortical derangement. The reverse face of the entire issue has been poorly if ever, scrutinized. The role of the peripheral nervous system in the installing and the maintaining of delusive ideas and convictions, albeit elusive, need to be addressed. The hallmark of bottom-up theory relies upon distorted primary processing of peripheral stimuli, wi...

 Open Access DOI:10.23937/IACPH-2017/1710003

Serum Copeptin Levels in Obstructive Sleep Apnea

Ebru Sengul Parlak, MD, Habibe Hezer, MD, Emine Arguder, MD, Hatice Kilic, MD, Murat Alisik, MD, Gokhan Yalciner, MD, Mehmet Ali Babademez, MD, Ozcan Erel, MD and Hatice Canan Hasanoglu, MD

Article Type: Research Article | First Published: June 21, 2019

Obstructive sleep apnea (OSA) is an important public health concern with numerous consequences at the societal level, including motor vehicle accidents, increased cardiovascular morbidity, metabolic dysfunction, and behavioral and cognitive deficit. OSA is characterized by a decrease in, or complete cessation of, airflow despite ongoing efforts to breathe, and is related to oxygen desaturation and sleep fragmentation....

 Open Access DOI:10.23937/IACPH-2017/1710002

The Impact of Thyroid Autoantibodies Positivity on In Vitro Fertilization Outcome: A Comprehensive Review

Sokratis Grigoriadis, Evangelos Maziotis, Mara Simopoulou, Konstantinos Sfakianoudis, Polina Giannelou, Anna Rapani, Petroula Tsioulou, Agni Pantou, Despina Tzanakaki, Konstantinos Pantos and Michael Koutsilieris

Article Type: Research Article | First Published: March 28, 2019

In Vitro Fertilization (IVF) has been employed for more than four decades. A crucial concern is the etiology of infertility due to the fact that it may range widely, from reproductive system anatomy and endometrium receptivity to multisystem disorders and several immunologic factors. Among the immune pathologies that could compromise fertility are the autoantibodies affecting thyroid function. Infertile women are in a great prevalence of thyroid autoimmune disorders. However, there are still uns...

 Open Access DOI:10.23937/iacph-2017/1710001

Human Physiology in Extreme Heat and Cold

Braian M Beker, Camila Cervellera, Antonella De Vito and Carlos G Musso

Article Type: Review Article | First Published: March 31, 2018

The interest in the human body physiological capacity to adapt to extreme heat and cold conditions has increased enormously in the last few decades because of global warming and the consequent changing temperatures. The human body has multiple thermoregulatory mechanisms to counter the external extreme temperatures whose main objective is to keep temperature homeostasis within normal values. As exposure time to these stressful conditions increases and the external temperature becomes even more e...

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