Clinical and Spirometric Characteristics of Premenstrual Asthma
S Aissani, I Ararem, H Haouichat, ME Haffaf and A Zitouni
Article Type: Research Article | First Published: June 06, 2019
Premenstrual asthma (APM) is often confused by the patient and/or doctor with the symptoms of asthma in general. The purpose of our study is to investigate the clinical and spirometric characteristics of APM. Prospective descriptive study from 2011 to 2017, on 95 non-menopausal asthma patients, divided into 2 with and without APM. They benefited on a single menstrual cycle of spirometry during the follicular phase, luteal and premenstrual and cutaneous tests....
Anaphylaxis to Water Caltrop (Singoda Flour): A Case Report
Omar E Mohamed, Toni Osborne, Jane Heslegrave and Mamidipudi Thirumala Krishna
Article Type: Case Report | First Published: May 25, 2019
A 57-year-old gentleman of an Asian background developed generalised urticaria, breathlessness and loss of consciousness following ingestion of Singoda flour (water caltrop flour). He was successfully resuscitated with adrenaline, chlorpheniramine and hydrocortisone. Acute mast cell tryptase was elevated and the skin prick test to water caltrop seed was positive. ...
H1-Antihistamines for Allergic Diseases: Old Aged but Not Old-Fashioned Drugs
Luisa Ricciardi, Fabiana Furci and Isola Stefania
Article Type: REVIEW ARTICLE | First Published: March 04, 2019
Histamine is a chemical messenger synthesized from the amino acid histidine by L-histidine decarboxylase. It plays an important role in the system of immunoregulation and in acute and chronic allergic inflammation binding to four subtypes of receptors H1, H2, H3 and H4, described as heptahelical transmembrane molecules that activate specific G-proteins. These receptors placed on the membranes of different cellular jambs (mast cells, endothelial cells, sensory nerve fibres, bronchial smooth muscl...