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Original Article Open Access

Cytotoxic Effect of Snake (Echis Carinatus) Venom on Human Embryonic Kidney Cells (HEK 293)

Mahboobeh Balali Bahadorani and Abbas Zare Mirakabadi
Clin Med Rev Case Rep Volume 3, Issue 9

Abstract: Background: The venom of snake (Echis carinatus) induces hemorrhage and necrosis locally at the bite site as well as acute renal failure (ARF) as a consequence of morphological and functional alterations in glomerular and tubular cells. Objectives: It is not clear that ARF results from a direct cytotoxic effect on renal epithelia or from a renal ischemia due to systemic hemodynamic disturbances. This work investigated the in vitro effect of Echis Carinatus crude venom, using cultured Human embryonic kidney (HEK 293) mono layers as a model to see the cytotoxic effect of Echis carinatus venom.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410132

Review Article Open Access

Advances in the Management of Skin Wounds with Synthetic Dressings

Fletes-Vargas Gabriela, Leon-Mancilla Benjamin and Esquivel-Solis Hugo
Clin Med Rev Case Rep Volume 3, Issue 9

Abstract: Treating wounds under normal wound healing processes often require little or no intervention, consisting primarily of debridement, as during the inflammatory stage the cells clear the wound to healing. However wound care professionals face many challenges in treating acute wounds with impairment on healing such as burn injuries or chronic wounds like diabetic, vascular and pressure ulcers. Wound healing is a complex process of several stages that requires being free of complications.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410131

Case Report Open Access

A Young Man with Joints Effusion without Trauma: It is a Rheumatic Disease

Cinzia Casu, Francesco Benazzo, Eleonora Bruschi, Franco Combi and Oscar Massimiliano Epis
Clin Med Rev Case Rep Volume 3, Issue 9

Abstract: The problem of swollen joints in athletes represents a typical risk following a sports injury, but this is not the only cause, although it is the most frequent one. Indeed inflammatory arthritis may also be a source of joint effusion. We report the case of a 21-year-old professional football player who suffered from pain and swelling in his joints after a mild sprain. He first underwent arthroscopy, followed by intra-articular steroid injections at a later stage.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410130

Case Series Open Access

Pseudoxanthoma Elasticum: An Unusual Cause of Hypertension in Child. About Three Cases Reports

A Dibi, M ElFahime, N Mouane, R Dafiri and A Bentahila
Clin Med Rev Case Rep Volume 3, Issue 9

Abstract: A 11-years-old boy was hospitalized for haematemesis. Clinical examination found a high blood pressure ranging at 170/90 mmHg. Renin activity was very high at 1825 mIU/l. The genetic study has identified 2 ABCC6 mutations in the composite state, what has allowed to confirm the diagnosis of PXE.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410129

Case Report Open Access

A Case of Spontaneous Regression of High-Grade Hepatocellular Carcinoma

Ghufran A, Agni R, Winslow E, Dalvie P and Agarwal PD
Clin Med Rev Case Rep Volume 3, Issue 9

Abstract: A 70-year-old South African male with a history of type 2 diabetes mellitus presented with vague abdominal discomfort of 2 months' duration. This was associated with anorexia and 15-pound weight loss over the preceding 6 months.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410128

Case Report Open Access

Malignant Peritoneal Mesothelioma in a Clerk: A Diagnostic Dilemma

Victoria Achaval Rodriguez, Patricia Moreira, Maria Camara, Pilar Rondon, Maria Garrido, Ricardo Hitt and Maria Jose Echarri
Clin Med Rev Case Rep Volume 3, Issue 9

Abstract: Diffuse malignant peritoneal mesothelioma (DMPM) represents one-fourth of all mesotheliomas. Association of asbestos exposure with DMPM has been observed, especially in males. Incidence is increasing worldwide and is not expected to peak for another 5 to 20 years. The majority of patients present with abdominal pain and distension, caused by accumulation of tumors and ascitic fluid.

PDF   | Full Text   DOI: 10.23937/2378-3656/1410127

Volume 3
Issue 9