A Brief Look at the Examination of Kidney Biopsies under Transmission Electron Microscope
Article Type: Short Commentary | First Published: December 24, 2018
Ultrastructural examination using the transmission electron microscope (TEM) has been used for diagnostic purposes in the evaluation of renal pathologies for more than 40 years. Previous studies have reported that electron microscopic ultrastructural examination makes a contribution of at least 25% in the diagnosis of renal pathologies, particularly including glomerulopathies such as nephrotic syndrome and minimal change disease. Several new glomerulopathies such as human immunodeficiency virus ...
Penile Prosthesis Surgery in Italy: Personal Experiences, Complications and Considerations after 552 Cases
Diego Pozza, Mariangela Pozza and Carlotta Pozza
Article Type: Review Article | First Published: December 19, 2018
The Implant of Penile Prostheses (Silicone, Malleable, Inflatable) represents an efficient solution for patients affected by Erectile Dysfunction (ED) and penetrating incapacity who do not respond to the other treatment modalities (PDE5i, PGE1, Vacuum Systems). Patients with penile prostheses regain the spontaneity of intercourses without having to assume drugs, to introduce mechanically medical substances or to activate complex mechanisms. Just like the whole field of prosthetic surgery, introd...
Female Hypospadias and Urinary Incontinence: Surgical Solution of a Little-Known Entity
Mario Lima, Niel Di Salvo, Tommaso Gargano and Giovanni Ruggeri
Article Type: Case Report | First Published: November 23, 2018
We describe the case of a female patient referred to our Institution for urinary incontinence likely due to hypospadias. As a matter of fact, her clinical history was way more complex. She was born at term, with no prenatal diagnostic suspicions. After toilet training achievement, between 2 and 3 years old, her mother noticed a continuous urinary dripping during day and night hours. Simultaneously, she started suffering from well-documented recurrent urinary tract infections (UTIs). She was firs...
Adrenocortical Carcinoma in a Young Patient: Report of a Rare Case and Review of the Literature at King Abdulaziz University Hospital
Sultan Almuallem, Shahad Abualhamael, Hala Mosli, Hisham Mosli and Murad Aljiffry
Article Type: Case Report | First Published: October 31, 2018
Adrenocortical tumors are rare neoplasms with poor prognosis and with an incidence of one in one million population. They are categorized as either functional (hormone-secreting) or silent and as either benign or malignant. We are reporting a very rare case of huge (16 cm) adrenocortical carcinoma in a 19-years-old male patient who presented with a progressively increasing right abdominal mass and uncontrolled systemic blood pressure for 2 years. Clinical exam was unremarkable for syndromic feat...
Supporting Evidence, Potential Adverse Effects, and known Drug Interactions of the Complementary Alternative Medicines which are Frequently used by Prostate Cancer Patients
Harmeet Deol, Alan Truong, Tibebe Woldemariam, Xiaodong Feng and Ruth Vinall
Article Type: Research article | First Published: October 18, 2018
A significant number of prostate cancer patients use complementary alternative medicines (CAMs) as an adjunct to their conventional treatment. Examples of CAMs that are frequently used by prostate cancer patients include green tea extract, lycopene, and pomegranate fruit extract. In many cases there is little if any clinical study-based evidence to support the efficacy of CAMs in this setting, and, importantly, some CAMs can cause serious adverse effects when taken a high doses and/or have signi...
Br, Fe, Rb, Sr, and Zn Levels in the Prostatic Secretion of Patients with Chronic Prostatitis
Vladimir Zaichick and Sofia Zaichick
Article Type: Research Article | First Published: October 12, 2018
Chronic prostatitis (CP) is an internationally important health problem of the man, particularly in developed countries. The aim of this exploratory study was to evaluate whether significant changes in the levels of Zn and some other trace elements of prostatic fluid exist in the inflamed prostate. Prostatic fluid levels of Br, Fe, Rb, Sr, and Zn were prospectively evaluated in 33 patients with CP and 42 healthy male inhabitants. Measurements were performed using 109Cd radionuclide-induced energ...
Penile Cancer: Case Report
Mehmet Solakhan and Ersan Bulut
Article Type: Case Report | First Published: October 11, 2018
Penile cancer is the most rarely observed cancer among male urogenital system tumors and is observed at an annual rate of 1/100000. Penile cancer risk increases significantly with increasing age, poor hygiene, and the presence of a foreskin. The most frequently observed type is the squamous cell carcinoma (SCC). Clinical examination of the inguinal lymph nodes is critical, as nodal involvement is a poor prognostic feature. Patients with T2 or higher-grade tumors and lymphovascular invasion are a...
Case of Penile Malignant Peripheral Nerve Sheath Tumor in a Twenty-Year-Old Male with Neurofibromatosis Type 1
Orchid Djahangirian, Ngoc-Anh Tran, Lilibeth Torno and Antoine Khoury
Article Type: Case Report | First Published: October 11, 2018
The patient's past medical history was significant for juvenile myelomonocytic leukemia (JMML) that was treated at the age of three years with chemotherapy, total body irradiation and splenectomy and bone marrow transplantation. The patient was clinically diagnosed with NF1 on the basis of multiple café au lait macules, cutaneous neurofibromas, and axillary and inguinal freckling. At the age of 19 years, imaging performed to evaluate a two-week history of coughing revealed a right paratracheal ...
Pure Primary Small Cell Carcinoma of Urinary Bladder: An Extreme Rarity
Sanjay Kumar, Namita Bhutani, Sant Prakash Kataria and Rajeev Sen
Article Type: Case Report | First Published: September 19, 2018
Small cell carcinoma of the urinary bladder is an extremely rare tumor accounting for less than 1% of all cancers arising from the bladder. Since the tumor is very rare, pathogenesis is uncertain. The tumor shares similar histological features with the small cell carcinoma originating at the other sites in body. However, its similar clinical features like the conventional transitional cell carcinoma of the bladder, tendency to present at a advanced stage and low immunoreactivity to the conventio...
Case Report: Fournier Gangrene Following Circumcision
Faisal Ghumman, Carlon Fitzpatrick, Seemin Nazad, Mishal Iqbal, Haider Iftikhar and Danielle Alexander
Article Type: Case Report | First Published: August 13, 2018
D.T. a 42-year-old male with no significant past medical history underwent circumcision for recurrent Balanitis using the sleeve technique. The procedure was uncomplicated, however a few adhesions with hyper-vascularity were found between the foreskin and the glans. No antibiotic prophylaxis was given intraoperatively. Good haemostasis was achieved with bipolar diathermy....
-2proPSA and Prostate Health Index Usefulness for the Diagnosis of Prostate Cancer for PSA Range between 3 and 10 ng/ml
J Juan Escudero, A Duran-Rivera, E Escudero, A Montoro, M Fabuel del Toro, M Ramos de Campos and E Lopez Alcina
Article Type: Original Article | First Published: Augsut 08, 2018
The prostate specific antigen (PSA) is a kallikrein protein family member and since the 1990s has been used as a biochemical marker for the early diagnosis of PCa. Since the introduction of PSA, we have witnessed the migration of this tumor to initial stages diagnosis, with a subsequent decrease in mortality. Even though PSA use is constantly challenged due to its low specificity, especially in what is known as the PSA grey area (between 4-10 ng/dL range), PSA is still the most utilized tumor ma...
The Impact of ABO Blood Group on Biochemical Recurrence after Radical Prostatectomy
Shahait M, Fares S, Mukherji D, Hout M, Bachir BG, Khauli R and Bulbul MA
Article Type: Original Article | First Published: July 11, 2018
The ABO antigens are expressed on the surface of red blood cells, epithelial cells, and endothelial cells. The association between different ABO blood group and several conditions such as VTE, CAD, and several neoplasms is well documented in the literature. The aim of this study is to examine the impact of ABO blood group on the biochemical failure after radical prostatectomy....