Reducing Non-Beneficial Renal Replacement Therapy in the ICU: Teaching Fellows to Negotiate a Time-Limited Trial
Paul J Hutchison, Yusra Cheema, Hala Yamout, Kathy Johnson Neely and Cybele Ghossein
Article Type: Research Article | First Published: June 27, 2016
Background:Acute kidney injury (AKI) carries a high mortality among patients treated in the intensive care unit (ICU). Continuous renal replacement therapy (CRRT) is used to treat complications of AKI, but it is often initiated in patients who have little hope of surviving. Objective:The authors sought to teach nephrology and pulmonary fellows how to utilize a time-limited trial strategy when discussing CRRT. ...
Outcomes Associated with a Heparin-Free Hemodialysis Protocol and Review of the Literature
Elizabeth Liang, Mayra Rodriguez, Melissa Mueller, Matthew K Abramowitz and Michele H Mokrzycki
Article Type: Review Article | First Published: May 20, 2016
Background: We aimed to determine outcomes associated with a heparin-free hemodialysis (H-HD) protocol in hospitalized patients. Methods: A retrospective study comparing 2 intra-dialytic heparin protocols: H + HD (routine heparin prime/bolus dosing) and H-HD (saline prime, heparin avoidance). HD circuit patency, need for intra-dialytic interventions and patient bleeding events were the outcomes....
Guillain-Barre Syndrome Associated with Cyclosporine A
Rizawati RI, Shamila K, Shafira MS and Ruslinda M
Article Type: Case Report | First Published: May 20, 2016
Guillain-Barre syndrome (GBS) is also known as an acute inflammatory demyelinating polyneuropathy (AIDP). It is an immune-mediated polyneuropathy commonly post-infectious in origin that presents with ascending weakness, loss of sensation and deep tendon reflexes resulting from demyelination of peripheral nerve. Drug-induced neuropathy has been describing before and remains a rare clinical entity. Development GBS after an episode of infections such as Campylobacter Jejuni, Epstein Barr Virus, and...
A Review on the Potential Role of Vitamin D and Mineral Metabolism on Chronic Fatigue Illnesses
Anna Dorothea Hock
Article Type: Review Article | First Published: May 14, 2016
Vitamin D3-insufficiency/ deficiency is a common condition arising from prevalent indoor activities and use of sunscreens with high protection factor. Lacking sunlight is frequent in patients suffering from chronic fatigue syndrome (CFS), fibromyalgia (FMS), and myalgic encephalopathy (ME) probably because of fatigue-related reduction of outdoor activity, high premorbid engagement in professional or caring activities, and preceding stressful life events....
Depression in Late-Life patients with End-Stage Renal Disease under Online-Haemodiafiltration is Associated with Low Social Support, Muscular Mass and Creatinine Serum Levels
Leonilde Amado, Veronica Poveda, Ricardo Ferreira, Nuno Ferreira, Vasco Miranda Laetitia Teixeira, Constanca Paul, Alice Santos-Silva and Elisio Costa
Article Type: Original Article | First Published: April 28, 2016
Patients with end-stage renal disease (ESRD) under dialysis showed a higher prevalence of depression, which is independently associated with non-adherence, hospitalization and mortality. We aimed to evaluate the prevalence of depression and associated variables, among ESRD late-life patients under online-haemodiafiltration (OL-HDF)....
HLA-B*60 and HLA-DR*14 Alleles might be associated with the Hyperuricemic and Possibly Metabolic Syndrome Status in Renal Transplant
Gabriela Hernandez-Molina, Joaquin Zuniga, Adriana Torres-Machorro, Lourdes Mena-Hernandez, Antonio Cachafeiro, Julio Granados and Marina Rull-Gabayet
Article Type: Research Article | First Published: January 31, 2016
Background: Hyperuricemia is frequent among renal transplant recipients. The role of the HLA system in the susceptibility of hyperuricemia is unknown. Methods: We evaluated the HLA-B and HLA-DRB1 distribution among 160 renal recipients: 132 with hyperuricemia (Group 1) and 28 free of it (Group 2) as well as 381 ethnic-specific Mexican-mestizo population historic controls. The HLA alleles were assessed by PCR-SSP and the HLA allele gene frequencies were obtained by direct gene counting and compar...