Journal of

Clinical Nephrology and Renal CareISSN: 2572-3286


 Open Access DOI:10.23937/2572-3286.1510011

Reducing Non-Beneficial Renal Replacement Therapy in the ICU: Teaching Fellows to Negotiate a Time-Limited Trial

Paul J Hutchison, Yusra Cheema, Hala Yamout, Kathy Johnson Neely and Cybele Ghossein

Article Type: Research Article | First Published: June 27, 2016

Background:Acute kidney injury (AKI) carries a high mortality among patients treated in the intensive care unit (ICU). Continuous renal replacement therapy (CRRT) is used to treat complications of AKI, but it is often initiated in patients who have little hope of surviving. Objective:The authors sought to teach nephrology and pulmonary fellows how to utilize a time-limited trial strategy when discussing CRRT. ...

 Open Access DOI:10.23937/2572-3286.1510010

Outcomes Associated with a Heparin-Free Hemodialysis Protocol and Review of the Literature

Elizabeth Liang, Mayra Rodriguez, Melissa Mueller, Matthew K Abramowitz and Michele H Mokrzycki

Article Type: Review Article | First Published: May 20, 2016

Background: We aimed to determine outcomes associated with a heparin-free hemodialysis (H-HD) protocol in hospitalized patients. Methods: A retrospective study comparing 2 intra-dialytic heparin protocols: H + HD (routine heparin prime/bolus dosing) and H-HD (saline prime, heparin avoidance). HD circuit patency, need for intra-dialytic interventions and patient bleeding events were the outcomes....

 Open Access DOI:10.23937/2572-3286.1510009

Guillain-Barre Syndrome Associated with Cyclosporine A

Rizawati RI, Shamila K, Shafira MS and Ruslinda M

Article Type: Case Report | First Published: May 20, 2016

Guillain-Barre syndrome (GBS) is also known as an acute inflammatory demyelinating polyneuropathy (AIDP). It is an immune-mediated polyneuropathy commonly post-infectious in origin that presents with ascending weakness, loss of sensation and deep tendon reflexes resulting from demyelination of peripheral nerve. Drug-induced neuropathy has been describing before and remains a rare clinical entity. Development GBS after an episode of infections such as Campylobacter Jejuni, Epstein Barr Virus, and...

 Open Access DOI:10.23937/2572-3286.1510008

A Review on the Potential Role of Vitamin D and Mineral Metabolism on Chronic Fatigue Illnesses

Anna Dorothea Hock

Article Type: Review Article | First Published: May 14, 2016

Vitamin D3-insufficiency/ deficiency is a common condition arising from prevalent indoor activities and use of sunscreens with high protection factor. Lacking sunlight is frequent in patients suffering from chronic fatigue syndrome (CFS), fibromyalgia (FMS), and myalgic encephalopathy (ME) probably because of fatigue-related reduction of outdoor activity, high premorbid engagement in professional or caring activities, and preceding stressful life events....

 Open Access DOI:10.23937/2572-3286.1510007

Depression in Late-Life patients with End-Stage Renal Disease under Online-Haemodiafiltration is Associated with Low Social Support, Muscular Mass and Creatinine Serum Levels

Leonilde Amado, Veronica Poveda, Ricardo Ferreira, Nuno Ferreira, Vasco Miranda Laetitia Teixeira, Constanca Paul, Alice Santos-Silva and Elisio Costa

Article Type: Original Article | First Published: April 28, 2016

Patients with end-stage renal disease (ESRD) under dialysis showed a higher prevalence of depression, which is independently associated with non-adherence, hospitalization and mortality. We aimed to evaluate the prevalence of depression and associated variables, among ESRD late-life patients under online-haemodiafiltration (OL-HDF)....

 Open Access DOI:10.23937/2572-3286.1510006

A Study Evaluating the Prevalence of Nephropathy among Type 2 Diabetes Patients Attending a Teaching Hospital in Malaysia

Salwa Selim Ibrahim Abougalambou, Syed Azhar Syed Sulaiman, Ayman S. Abougalambou and Mohamed Azmi Hassali

Article Type: Research Article | First Published: March 23, 2016

Nephropathy is a major cause of illness and death of patients with type 2 diabetes mellitus (DM), Diabetic nephropathy has become the leading cause of end-stage renal disease; kidney failure that requires a lifetime of dialysis. It develops in about 20-40% of Type 2 Diabetes patients....

 Open Access DOI:10.23937/2572-3286.1510005

Patient Perception of Treatment Success: A Qualitative Interview Study in Patients with End-stage Renal Disease undergoing Hemodialysis

Anna Ryden, Matthew Wolfe and Mona L Martin

Article Type: Research Article | First Published: February 01, 2016

End-stage renal disease treated with hemodialysis (ESRD-HD) is associated with poor outcomes for patients and can substantially reduce health-related quality of life (HRQL). Alongside drug development for this patient group, there is a need for a better understanding of patients' perceptions of their condition, their symptoms and the impact ESRD-HD has on their lives. Here, we report data from qualitative, semi-structured, concept-elicitation interviews, conducted as part of a phase 2 clinical s...

 Open Access DOI:10.23937/2572-3286.1510004

HLA-B*60 and HLA-DR*14 Alleles might be associated with the Hyperuricemic and Possibly Metabolic Syndrome Status in Renal Transplant

Gabriela Hernandez-Molina, Joaquin Zuniga, Adriana Torres-Machorro, Lourdes Mena-Hernandez, Antonio Cachafeiro, Julio Granados and Marina Rull-Gabayet

Article Type: Research Article | First Published: January 31, 2016

Background: Hyperuricemia is frequent among renal transplant recipients. The role of the HLA system in the susceptibility of hyperuricemia is unknown. Methods: We evaluated the HLA-B and HLA-DRB1 distribution among 160 renal recipients: 132 with hyperuricemia (Group 1) and 28 free of it (Group 2) as well as 381 ethnic-specific Mexican-mestizo population historic controls. The HLA alleles were assessed by PCR-SSP and the HLA allele gene frequencies were obtained by direct gene counting and compar...

 Open Access DOI:10.23937/2572-3286.1510003

Assessing Renal Function in Adult Myelomeningocele Patients: Correlation between Volumetric- and Creatinine-based Measurements

Vij Sarah C, Karim Wadih, Luzny Patrik, Myers Jeremy B, Emilio Poggio, Herts Brian and Wood Hadley

Article Type: Research Article | First Published: January 31, 2016

Renal volume-based estimates of glomerular filtration rate (GFR) using computed tomography (CT) in renal donor populations have been described. We hypothesized that the same technology would be especially useful in myelomeningocele (MMC) patients for whom standard methods of GFR assessment are inaccurate....

Volume 2
Issue 1