Journal of

Clinical Nephrology and Renal CareISSN: 2572-3286

Early Online

 Open Access DOI:10.23937/2572-3286.1510039

Utility of Trend of Nephrocheck (IGFBP7 × TIMP-2) Biomarker for Early Identification of Acute Kidney Injury in Critically Ill Patients with Sepsis or Respiratory Failure

Ena Gupta, Ravi Sunderkrishnan, Nimrita Sidhu, Maria P Martinez Cantarin, Michael Baram and Bharat Awsare

Article Type: Original Research | First Published: August 27, 2018

Many studies have shown the association between acute kidney injury (AKI) and morbidity and mortality in the Intensive Care Unit (ICU). Traditional measures of AKI, such as serum creatinine and urine output, fail to show dynamic changes in renal function. A feasibility study was performed to evaluate the Nephrocheck test system which comprises of two biomarkers (Insulin-like growth factor binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP-2)) to screen for patients at ...

 Open Access DOI:10.23937/2572-3286.1510038

Tolerability of Double Filtration Plasmapheresis (DFPP) in the Remission-Induction of Severe Lupus Nephritis

Shafira Mohamad Sha

Article Type: Review Article | First Published: July 04, 2018

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by a multitude of autoantibody production. Lupus nephritis (LN) is one of its most severe manifestations and its treatment is well established with the usage of immunosuppressions. However the use of these immunosuppressions at high doses are fraught with adverse effects including infections, subfertility and even malignancy....

Volume 4
Issue 2