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Geriatric Medicine and GerontologyISSN: 2469-5858

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 Open Access DOI:10.23937/2469-5858/1510057

Optimal Time to Administer Once-Daily Oral Cardiovascular Agents: Evidence Based on Randomized Clinical Trials in the Last Ten Years

Shu-yi Zhou, Ling-ling Zhu and Quan Zhou

Article Type: Research Article | First Published: December 03, 2018

Sporadic studies have investigated the influence of administration time (morning versus evening) on the efficacy and safety of once-daily medications. It is necessary to let clinicians know the developments during the last ten years. Focusing on chronotherapeutic topic, a literature search on randomized controlled trials (RCTs) of oral once-daily cardiovascular agents was conducted using PubMed, Cochrane Library, Scopus and Web of Science from Jan 01, 2008 to Sept 30, 2018....

 Open Access DOI:10.23937/2469-5858/1510056

Vertebral Body Erosion in Geriatric Patient: Case Reports and Systematic Review of Literature

Elif Evrim EKIN, Hulya KURTUL YILDIZ and Muhittin Emre ALTUNRENDE

Article Type: Case Report | First Published: November 03, 2018

A 71-year-old man with low back pain for more than a year, cortical erosion and vertebral cyst formation of L4 vertebral body were diagnosed on lumbar MRI. There was no compression fracture or bone marrow edema. The fusiform unruptured aneurysmatic dilatation of abdominal aorta was seen adjacent to the vertebral cyst (Figure 1 and Figure 2). The vertebral cyst was thought to be associated with abdominal aortic aneurysm (AAA). The aortic wall defect or paraaortic hematoma was not established. Aft...

 Open Access DOI:10.23937/2469-5858/1510055

Screening Colonoscopy Adverse Events in Aging Adults: Does Frailty Matter?

Toosizadeh N, Ehsani H, Taleban S, Golden T, Tirambulo C and Mohler J

Article Type: Research Article | First Published: November 01, 2018

Socio-demographic data, the Charlson Comorbidity Index (CCI), and UEF clinical frailty syndrome classification (non-frail versus pre-frail/frail) were assessed prior to colonoscopy, and acute colonoscopy outcomes were stratified into three severity categories. Logistic regression and ANOVA/ANCOVA were employed. 41% of non-frail had one or more complications, versus 70% of pre-frail/frail group. Those in the pre-frail/frail group had nearly three times the number of acute colonoscopy complication...

Volume 4
Issue 4