International Archives of

Translational MedicineISSN: 2572-4142

Current Issue

 Open Access DOI:10.23937/2572-4142.1510010

Is Immunohistochemistry Enough to Diagnose Xp11.2 Renal Cell Carcinoma?

Paulo Victor Zattar Ribeiro and Leonora Zonula Pope, MD

Article Type: Commentary | First Published: February 05, 2021

The correct diagnosis methods of Renal Cell Carcinoma (RCC) with Xp11.2 translocations are controversial in the current literature. Due to the possible failures of immunohistochemistry alone. So we present a possible scientific based answer with the articles yet available. Renal cell carcinoma (RCC) with Xp11.2 translocations was delineated as a distinct entity in 2004 by the World Health Organization. It was primarily associated with TFE3 gene fusion and TFE3 protein overexpression in immunohis...

Volume 6
Issue 1