International Journal of

Immunology and ImmunotherapyISSN: 2378-3672

Early Online

 Open Access DOI:10.23937/2378-3672/1410070

The Ageing Immune System- Implications for COVID-19

Kelechi Ukaegbu

Article Type: Review Article | First Published: 2024/03/04

Ageing is a slow and continuous process that is associated with the decline in the functioning immune system. These changes are now recognized and appreciated under the canopy term ‘Immuno-senescence’ [1]. Immuno-senescence is not due to a lack of immune cells but reduced diversity in the repertoire - with reduced naive cells and increased memory cells. Secondly, the ageing immune system is subject to inflammaging, elevated self-reactivity leading to chronic low-grade inflammation....

 Open Access DOI:10.23937/2378-3672/1410065

Evaluation of Some Inflammatory Cytokines Levels as A Marker for Diabetes

Mabrouk A Abo-Zaid, Soha S Mohammed and Ahmed H Ismail

Article Type: Research Article | First Published: September 05, 2022

From the different causes of death diabetes has an advanced rank in the first 10. So the aim of this study was to relate between some pro-inflammatory cytokines (TNF-α, IL-6, and TGF-β1) and infection with diabetes as biomarkers for infection. Forty male Wister albino Streptozotocin (STZ) induced diabetic rats were used as a model for estimation of the related cytokines. The animals were divided in two groups, the first group was given a placebo, whereas the second was given Streptozotocin at ...

 Open Access DOI:10.23937/2378-3672/1410064

Diagnosis and Treatment of Autoimmune Diseases by the Method of Resonance Medicine

Praznikov Viktorm, MD, PhD

Article Type: Literature Review | First Published: May 26, 2022

Resonant methods for the study of matter have found wide application in physics, chemistry, biology, and medicine. For example, Nuclear Magnetic Resonance (NMR)....

 Open Access DOI:10.23937/2378-3672/1410063

Petechial Rash and Thrombocytopenia after the Booster Dose of Covid-19 Vaccine: A Case Report and Literature Review

Selia Chowdhury, Samia Chowdhury, Nurjahan Shipa Chowdhury, Athanasios Patousis, Anna Gerothanasi and Panagiotis Patousis

Article Type: Case Report | First Published: April 25, 2022

Since December 2020, the Pfizer-BioNTech BNT16B2b2 mRNA vaccine has been widely used to prevent COVID-19 infection. Vaccination is now widely regarded as the most effective way to reduce the pandemic's morbidity and death. Except for mild and infrequent adverse effects, almost all vaccinations are considered safe. One of the documented adverse effects of the COVID-19 immunizations is vaccine-induced immune thrombocytopenic purpura. We discuss the case of a 25-year-old gentleman who received an u...

 Open Access DOI:10.23937/2378-3672/1410062

Immuno-Therapy in Lung Cancer - How Does Immuno-therapy for Lung Cancer Change Patients' Vision?

Tshetiz Dahal, MBBS

Article Type: Research Article | First Published: March 23, 2022

Survival rates of metastatic lung cancer including non-small cell lung cancer (NSCLC) and poor lung cell cancer (SCLC) are poor with a survival rate of less than 5%. The use of cell-oriented therapies has improved the overall survival of the median (OS) in a limited group of NSCLC patients whose tumors undergo certain genetic mutations. However in a large group of NSCLC and SCLC cell mutations are not available to lead to targeted targeted treatment. Recent positive results from new medical rese...

 Open Access DOI:10.23937/2378-3672/1410061

Expression Pattern of IL-6 and Interferon Gamma (IFN-γ) from Chronic Hepatitis B Genotype D Patients from Nepal

Smita Shrestha, Mukunda Sharma and Krishna Das Manandhar

Article Type: Research Article | First Published: January 09, 2022

Hepatitis B virus (HBV) Genotype D has been associated with chronicity leading to Liver cirrhosis and Hepatocellular carcinoma. The Genotype is one of the most common genotypes detected in Nepal. However, the expression analysis for cytokines like IFNγ and IL-6 which could help in boosting the immunity in patients has not been done. The study aims to investigate the expression of IFNγ and IL-6 in chronic HBV patients with Genotype D. Sera samples from 43 Hepatitis B infected patients were coll...

Volume 9
Issue 1