International Journal of

Medical Nano ResearchISSN: 2378-3664

Early Online

 Open Access DOI:10.23937/2378-3664.1410027

Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers

S Huclier-Markai, E Ntsiba, E Thomas, C Alliot, CS Cutler, F Luxc and O Tillement

Article Type: RESEARCH ARTICLE | First Published: February 25, 2019

Diagnostics that combine imaging techniques such as PET and MRI could enhance disease detection and location if effective multimodal contrast agents can be developed. A nanoparticle called AGuIX has been developed that is comprised of gadolinium-bound by chelates and additional free chelates that can be further labelled with radioactive isotopes enabling both PET and MRI imaging. Herein, we describe the size characterization of these nanoparticles together with their size distribution, which is ...

Volume 6
Issue 1