International Archives of Translational Medicine is an Open Access, peer reviewed, international online journal that aims to publish premier papers on all the areas of translational medicine. International Archives of Translational Medicine focus on understanding the molecular mechanism of diseases, including disease biomarkers, molecular diagnosis, drug delivery, target therapies.
International Archives of Translational Medicine welcomes articles in the form of original research, reviews, case reports, commentaries, clinical investigations etc., in the field of translational Medicine. International Archives of Translational Medicine ensures the faster publication of high quality articles. International Archives of Translational Medicine is a yearly journal which accelerates the pace of research updates, discovery and innovation in various aspects of translational medicine.
The journal ensures the faster publication of high quality articles with the support of its eminent Editorial board members. Two independent review comments followed by editor's decision will be considered to publish the article. All the published content with the journal is made freely accessible without any restriction barriers under Creative Commons Attribution License.
Articles Search by Keyword | Journal title | Author name | DOI
Open Access DOI:10.23937/2572-4142.1510010
Paulo Victor Zattar Ribeiro and Leonora Zonula Pope, MD
Article Type: Commentary | First Published: February 05, 2021
The correct diagnosis methods of Renal Cell Carcinoma (RCC) with Xp11.2 translocations are controversial in the current literature. Due to the possible failures of immunohistochemistry alone. So we present a possible scientific based answer with the articles yet available. Renal cell carcinoma (RCC) with Xp11.2 translocations was delineated as a distinct entity in 2004 by the World Health Organization. It was primarily associated with TFE3 gene fusion and TFE3 protein overexpression in immunohis...
Open Access DOI:10.23937/2572-4142.1510009
Tatiana Cristina Figueira Polo, Silvia Justina Papini, Katia Portero Sloan, Patricia Baston Frenhani and Roberto Carlos Burini
Article Type: Original Research | First Published: August 26, 2019
Results of epidemiological studies that have evaluated the relationship between dairy food consumption and risk of metabolic syndrome are not consistent and sometimes controversial. This study included 763 individuals clinically selected for the lifestyle modification program “Move for health” and fulfilling the inclusion criteria of having data of socioeconomic, demographic, physical activity and dietary assessments, as well as the anthropometric, clinical and biochemical assessments for th...
Open Access DOI:10.23937/2572-4142.1510008
Jean-Jacques Braun, MD, Marion Renaud, MD, Sebastien Moliere, MD, Vincent Noblet, MD, Stephane Kremer, MD, Helene Dollfus, MD and Sophie Riehm, MD
Article Type: Original Article | First Published: April 15, 2019
Congenital anosmia (CA) is rare comparatively to acquired anosmia. The pathophysiology and the genetic background remain poorly understood. This study aims to review the main clinical and Magnetic Resonance Imaging (MRI) findings to discuss the diagnostic strategy, the pathophysiology and the genetic basis of the different forms of CA. A series of 60 patients with congenital anosmia was reviewed retrospectively out of 425 non-sinus-related anosmia and compared to the literature data. CA was asse...
Open Access DOI:10.23937/2572-4142.1510007
Zuheir Ahmed Hasan, PhD, Ghada Al-Kafaji, PhD, Maryam Isa Al-Sherawi, PhD, Rima Abdul Razzak, PhD, Diab Eltayeb, PhD, Cristina Skrypnk, MD, PhD and Moiz Bakhiet, MD, PhD
Article Type: Original Article | First Published: March 11, 2019
Autism is a complex neurodevelopmental disorder, the pathogenesis of which remains unclear. Recent research suggests a possible role of hormonal abnormalities in the pathogenicity of autism. In this investigation, we measured serum levels of leptin, ghrelin, and growth hormone (GH) in 40 age-matched Bahraini children, 20 with autism (16 males and 4 females) and 20 healthy children (13 males and 7 females). Hormonal levels were measured by enzyme-linked immunosorbent assay method....
Open Access DOI:10.23937/2572-4142.1510006
Estela S. Estape, Lorena Gonzalez-Sepulveda, Wen Wei, Ingrid Rodriguez-Rivera and Ivette Torres-Negron
Article Type: ORIGINAL ARTICLE | First Published: September 06, 2018
Numerous studies have demonstrated a strong relationship between circulating levels of marinobufagenin (MBG) and salt-sensitivity. Since salt-sensitive hypertensives have increased plasma levels of MBG and are known to be at a higher risk of having cardiovascular events, stroke and increased mortality, we evaluated the possibility of an association between MBG and ischemic stroke. In this pilot study, we determined plasma MBG levels in patients after surviving an ischemic stroke compared to simi...
Open Access DOI:10.23937/2572-4142.1510005
Schmid F, Zuhlke I, Hein H, Magnussen H and Jorres RA
Article Type: Research Article | First Published: December 13, 2017
The standard treatment of patients with COPD comprises β2-agonists and anticholinergics. Both drugs exert similar effects in terms of bronchodilation but in the clinical use we observed that some patients reported a stable degree or even an increase of dyspnea after the administration of β2-agonists compared to anticholinergics....
Open Access DOI:10.23937/2572-4142.1510004
Lloyd Reeve Johnson, Harry Mc Connell and Alston Unwin
Article Type: Case Report | First Published: October 09, 2017
Epilepsy is the most common chronic neurological condition in humans and dogs. Unexplained death is up to three times greater in epileptic humans than the general population with less definitive but supportive evidence of this trend in dogs....
Open Access DOI:10.23937/2572-4142.1510003
Article Type: Review Article | First Published: December 07, 2016
The quality of healthcare, drug innovation, treatment decisions and even approval of drugs are all transaction dependent. Each decision after we seek medical attention is part of a predictable sequence, the totality of which describes the healthcare system. The interplay between the patient, clinician, pharmaceutical company, government or medical insurances paying bills, and, regulators controlling access to the healthcare market is therefore predictable and open to influence. Each of participa...
Open Access DOI:10.23937/2572-4142.1510002
Estela S Estape, Ivette Torres-Negron, Lorena Gonzalez and Manuel Martinez Maldonado
Article Type: Research Article | First Published: May 30, 2015
The Dahl salt-sensitive rat is a well-established model to study essential hypertension. We fist described a subgroup of these rats based on the unique response pattern in systolic blood pressure during the fist weeks of exposure to a high salt diet that included cataract formation. We classified this group as cataractprone Dahl salt-sensitive rat. We also were able to predict and prevent cataract formation in these rats. Further studies showed an inhibition of lens Na, K-ATPase activity which m...
Open Access DOI:10.23937/2572-4142.1510001
Article Type: Editorial | First Published: February 25, 2015
With great pleasure, I welcome you to the inaugural issue of the International Archives of Translational Medicine. The rapid progress in basic medical research is constantly reframing the paradigm how we prevent, diagnose and treat human diseases....
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