Review Timeline | CrossMark Policy | ClinMed Features
logo
International Journal of

Respiratory and Pulmonary MedicineISSN: 2378-3516

Archive

 Open Access DOI:10.23937/2378-3516/1410195

Sotatercept in the Treatment of Pulmonary Arterial Hypertension: A Comprehensive Narrative Review of Mechanism, Efficacy, and Future Directions

Niroshan Ranjan, MD, Ahmed Ahmed, MD, Jordana Woods, MD, Ramaneshwar Selvaraj, MBBS, Mihir Patel, DO, Yaman Dalati, DO, Vidushan Sabanathan and Thanujan Thangadurai, MD

Article Type: Narrative Review | Indexed Archive: Volume 12

Pulmonary arterial hypertension (PAH) is a progressive vascular remodeling disease with elevated pulmonary vascular resistance that is lethal. While therapeutic progress was recently made with endothelin, nitric oxide, and prostacyclin pathway-based therapy for the treatment of PAH, the disease is currently incurable with a high cost of morbidity and mortality. Sotatercept, a new activin receptor IIA-Fc fusion protein, may prove to be a gamechanger as a therapeutic agent for the treatment of PAH...

 Open Access DOI:10.23937/2378-3516/1410194

Addressing Environmental Factors in COPD: The Role of HEPA Filters in Indoor Air Quality

Nishant Allena, Anandu Mathews Anto, Luis Espinosa, Sneha Khanal and Trupti Vakde

Article Type: COPD is a major public health issue globally, resulting in Check for updates unit increase in ambien | Indexed Archive: Volume 12

COPD is a major public health issue globally, resulting in Check for updates unit increase in ambient air pollutant exposure is significant morbidity, loss of productivity, and increased health expenditure. Air pollution is considered the primary factor leading to the development and progression of COPD. While the role of outdoor air pollution was well outlined, studies have looked at how indoor air quality and indoor air pollution can cause or worsen the disease. ...

 Open Access DOI:10.23937/2378-3516/1410193

Assessing Measures for Preventing Ventilator Associated Pneumonia among Nurses Working in Intensive Care Units: A Case of Two Selected Referral and Teaching Hospitals in Kigali

Ernest Ruririmbwa, Busisiwe Rosemary Bhengu, Girum Sebsibie Teshome

Article Type: Original Research | Indexed Archive: Volume 12

Ventilator associated pneumonia (VAP) is the most common hospital acquired infection in intensive care units (ICUs). This infection has been found to be associated with increased duration on mechanical ventilation, longer hospital stay, higher treatment costs as well as increased rate of morbidity and mortality....

Volume 12
Issue 1