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Open Access DOI:10.23937/2690-3172/1710012
C.E.M. Fernandes, E.M. Guilherme, K.R. Serafim, A.C.L. Gianlorenço and R. Mattioli
Article Type: Research Article | First Published: April 21, 2021
The cerebellum is known to participate in motor functions, but the role of the histaminergic system, and specifically the H4 receptors, in its functions is still unclear. In the present study, we investigated the effects of intravermis microinjections of an H4 receptor agonist (VUF-8430) on mice behavior undergoing a rotarod (Experiment 1) and open field (Experiment 2) test. The cerebellar vermis of male mice was implanted with a single guide cannula. All experiments were performed on two consec...
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