International Journal of

Neurology and NeurotherapyISSN: 2378-3001


 Open Access DOI:10.23937/2378-3001/3/6/1063

Effectiveness of A Fall Prevention Protocol for Patients with Ischemic Stroke During Hospitalization

Yanxia Huang, Ting Luo, Lihui Huang, Lei Zhang, and Hongmei Tao

Article Type: Original Research | First Published: December 15 2016

Patients with ischemic stroke are at high risk of fall. However, few study focused on fall prevention for patients with ischemic stroke in hospital. The aims of the study were to find out the causes of falling in the inpatient ischemic stroke patients and formulate a fall prevention protocol for them....

 Open Access DOI:10.23937/2378-3001/3/6/1062

A Combinatory Therapy Continuously Improves Memory in a Case of Probable Alzheimer's Disease with Head Trauma for Nearly Two Years

Jing Shi, Xuekai Zhang, Mingqing Wei, Jingnian Ni, Ting Li Mphil and Jinzhou Tian

Article Type: Case Report | First Published: December 05, 2016

Since the worldwide demographic ageing, prevalence of the most common cause of dementia in the elderly, Alzheimer's disease (AD), will increase dramatically. Although it has been intensively researched for many years, there are still limited treatments for AD. Currently approved pharmacotherapy is generally considered have symptom-relieving rather than disease processing modifying effects. Meanwhile, there are efficacy limits of such medicines, for example, donepezil efficacy starts to decline f...

 Open Access DOI:10.23937/2378-3001/3/6/1061

Depression in Parkinson's Disease is Associated with a Serotoninergic System Change Secondary to Neuroinflammation

Ronise M Santiago, Maria ABF Vital, Marcelo D O Sato and Gustavo P Adam

Article Type: Research Report | First Published: December 03, 2016

Depression is a common psychiatric disorder in patients with Parkinson's disease (PD), being more prevalent in PD than in any other chronic disabling disease. Its cause, nevertheless, has not yet been elucidated. According to some authors, there is a decrease in serotonin (5-HT) levels compensatory to dopaminergic release impairment, but new evidence suggests that chronic inflammation may be a more likely etiogenic factor to depression. The inflammatory hypothesis states that depression is cause...

 Open Access DOI:10.23937/2378-3001/3/6/1060

The Damaging Impact of Chronic Heart Failure on A Critical Interoreceptor and the Therapy for it

Robert S Fitzgerald

Article Type: Mini Overview | First Published: December 01, 2016

Congestive Heart Failure (CHF) is among the heart diseases which accounted for > 54% of deaths world-wide in 2013 in a World Health Organizations report. CHF patients most often have a more sensitized carotid body (CB) chemoreceptor than normal. CB neural output stimulates output from the sympathetic nervous system. Increased CB output in CHF has in animal models been attributed to a loss of shear stress on the luminal surfaces of the CBs' vascular endothelial cells....

 Open Access DOI:10.23937/2378-3001/3/6/1059

Abnormal Plasticity and Epigenesis in Epileptic Seizures of an EL Mouse

Jiro Suzuki

Article Type: Rather Short Review | First Published: November 30, 2016

The EL mice were exposed to the natural proprioceptive sensory stimulation of tossing the animal into the air to provoke an epileptic seizure, which results from an increase in the excitability of the cortical neurons due to low activities of Glutamic acid decarboxylase (GAD) and Gamma-amino butyric acid (GABA). The seizures develop due to the abnormal plasticity and eventually occur spontaneously....

Volume 3
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