Early Online
Open Access DOI:10.23937/2378-3001/1410125
Paula Maria Neufeld, Jonas Frai, Veronika Matschke, Carsten Theiss and Sarah Stahlke
Article Type: Original Article | First Published: 2023/12/30
In this study, we evaluated the stability of three common housekeeping genes, GAPDH, beta-Actin, and 18S-rRNA, in human neuroblastoma SHSY-5Y cells exposed to varying levels of steroid hormones like progesterone (P4) and testosterone. Housekeeping genes serve as reliable internal controls, assumed to maintain consistent expression across diverse tissues and experimental conditions. Since steroid hormones act as ligand-activated transcription factors, directly impacting gene transcription, the id...
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