International Journal of

Neurology and NeurotherapyISSN: 2378-3001

Early Online

 Open Access DOI:10.23937/2378-3001/1410080

Charcot-Marie-Tooth Disease Type 1A and Inflammatory-Demyelinating Lesions in the Central Nervous System

Daniel A Garcia-Estevez, Carmen Cid-Rodriguez and Guillermo Ozaita-Arteche

Article Type: CASE REPORT | First Published: February 23, 2019

Charcot-Marie-Tooth disease (CMT) is a hereditary sensorimotor polyneuropathy which is occasionally associated with demyelinating lesions in the central nervous system, although it remains unclear whether this finding is coincidental or whether the two processes share a common pathogenic mechanism. A male patient with sensorimotor polyneuropathy presented with symptoms consistent with cauda equina syndrome at age 47 in relation to an inflammatory lesion in the conus medullaris. Six years later, ...

 Open Access DOI:10.23937/2378-3001/1410079

Cognitive-Functional Interaction in Patients with Vascular Dementia

Edith Labos, Karina Zabala, Miriam Del Rio, Sofia Trojanowski, Alejandro Renato and Osvaldo Fustinoni

Article Type: Review Article | First Published: February 16, 2019

Vascular Dementia (VD) is the most frequent type of dementia after dementia of the Alzheimer's type (DAT). Its prevalence increases exponentially with age and its risk doubles every 5.3 years. Nevertheless, up to 32% of DAT cases have coexisting cerebrovascular lesions. Cognitive deficits appear very early in patients with cerebrovascular risk. In more than 1000 patients with arterial hypertension recently studied in Argentina, global cognitive impairment was 22.1%. Executive function and semant...

Volume 6
Issue 1