Open Access DOI:10.23937/2572-4215.1510027
Treatment of Severe Trismus during Locked-In Syndrome Secondary to Central Pontine Myelinolysis Using Onabotulinum Toxin-A: Case Report
Wiaam Elkhatib, MD and Whitney Pratt, MD, PhD
Article Type: Case Report | First Published: February 19, 2023
Trismus in adults has a wide range of known causes, though few cases have ever been reported secondary to central pontine myelinolysis (CPM). This report describes a case of severe trismus without clear etiology successfully treated with onabotulinum toxin-A following development of CPM. Patient was a female aged in her early thirties who presented to the hospital with ascending weakness five days following hyponatremia correction at rates within guideline recommendations. MRI revealed increased...
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