Waheed A, Kossor D, Collins W, Camie A (2018) Effect of Specific Music on Psychoneuroimmunological Responses. Int J Oncol Res 1:011. 10.23937/ijor-2017/1710011


© 2018 Waheed A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ORIGINAL ARTICLE | OPEN ACCESS DOI: 10.23937/ijor-2017/1710011

Effect of Specific Music on Psychoneuroimmunological Responses

Abdul Waheed1*, David Kossor2, William Collins3 and Amy Camie4*

1Biochemistry and Molecular Biology, St. Louis University, USA

2Principal/CEO, Syncratic Therapies LLC, Charlotte, USA

3Principal/Owner, Reintegrative Health Institute, St. Louis University, USA

4Composer, Professional Harpist, St. Louis, USA


A pilot study was done to measure quantitative EEG (qEEG) brainwave frequencies and behavioral indices of five women undergoing chemotherapy treatment for cancer, before and after listening to specific music (The Magic Mirror-Inspired Reflections solo harp CD written, performed and recorded by Amy Camie) once a day for ten days. Following treatments, the EEG profile for all five participants improved and subjective reports from daily questionnaires confirmed a positive effect of the music.

A further proof of principle investigation of potential effects of listening to The Magic Mirror music on physiological and psychological stress and immunoreactivity was done in ten healthy individuals by measuring biomarkers of physiological and psychological stress (carbonic anhydrase VI (CAVI), IgA, IgG, and ά-amylase) in saliva samples that were collected from each individual before and after listening to the 23-minute CD. Additional samples were collected 24 hours later. Secretory IgA, IgG, and CAVI biomarkers were increased in saliva and remained high until 24 hours after music, suggesting The Magic Mirror produced measurable effects on immune response in individuals.

A second proof of principle study looked at the duration of the effects. Similar to the first study, the second study was done repeating the same study design, where levels of secretory IgA, IgG, ά-amylase, and CAVI in saliva samples again were shown to increase during and after listening, and these changes persisted for 2-3 days. These results suggest that listening to The Magic Mirror CD produces neurosecretory responses indicative of reduced physiological and psychological stress and may be a useful adjunctive therapy for cancer or physiologically stressed patients.