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International Journal of
Virology and AIDS ISSN: 2469-567X

Citation

NIAMA RF, MOUNDOSSO TS, PEMBE IM, BAYONNE-KOMBO ES, OSSIBI IBARA RB, et al. (2019) HIV and Hepatitis Coinfection among HIV-1 Infected Individuals in Republic of the Congo. Int J Virol AIDS 6:055. doi.org/10.23937/2469-567X/1510055

Copyright

© 2019 NIAMA RF, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ORIGINAL ARTICLE | OPEN ACCESS DOI: 10.23937/2469-567X/1510055

HIV and Hepatitis Coinfection among HIV-1 Infected Individuals in Republic of the Congo

NIAMA Roch Fabien1,2*, MOUNDOSSO Thierry Stéphane1, PEMBE ISSAMOU MAYENGUE1,2, BAYONNE-KOMBO Edith Sophie4, OSSIBI IBARA Roland Bienvenu4, DIAFOUKA Merlin5, MAHAMBOU NSONDE Dominique5, LOUZOLO Igor1, LOUKABOU Bongolo Nadia Claricelle1, DZABATOU-BABEAUX Angélie Serge Patrick6, MALOUMBI Marie Geneviève3 and PARRA Henri-Joseph1

1Laboratoire National de Sante Publique, Unité de Biologie Moléculaire, République du Congo

2Faculté des Sciences et Techniques, Université Marien Ngouabi, République du Congo

3Ecole Nationale Supérieure Polytechnique, Université Marien Ngouabi, République du Congo

4Faculté des Sciences de la Santé, Université Marien Ngouabi, République du Congo

5Centre de Traitement Ambulatoire (CTA) de Brazzaville, République du Congo

6Programme National de Lutte Contre le Sida, Ministère de la Santé et de la population, République du Congo

Abstract

Background

HIV and Hepatitis co-infection is common and contribute significantly to morbidity and mortality in persons living with HIV (PLWH). The objective of this study was to determine the prevalence of this co-infection in patients receiving second-line antiretroviral therapy in Pointe-Noire and Brazzaville.

Methods

Human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV) infections are common worldwide and are a major public health problem. The similarity of their transmission pathways (unprotected sex, blood transfusion, injecting drug use, mother-to-child transmission) probably explains the high frequency of co-infections of these viruses.

Results

Out of a total of 261 HIV-positive patients, women accounted for more than half (55.17%), and slightly more than half (54.88%) were older than 40 years. Regarding co-infection, 4.21% (11/261) were co-infected with HIV/HBV, 6.89% (18/261) were co-infected with HIV/HCV and 0.38% (1/261) carried all three viruses. The overall prevalence of patients co-infected with hepatitis and HIV was 11.49%. Conversely, CD4+ cells are low, and less than 350 cells/μl stained CD4+ positive in all groups.

Conclusion

Although the rate of HIV and hepatitis co-infection seem to be low compare with what is known in sub-Saharan Africa, our results highlight the importance of screening PLWH for hepatitis in developing countries, especially in Congo.