International Journal of

Virology and AIDSISSN: 2469-567X

Early Online

 Open Access DOI:10.23937/2469-567X/1510094

Understanding Low Vaccine Uptake in African, Caribbean, and Black Populations Relative to Public Health in High-Income Countries: A Scoping Review Protocol

Josephine Etowa, Sheryl Beauchamp and Victoria Cole

Article Type: Original Research | First Published: 2024/03/21

Vaccination has significantly contributed to reducing once common and even deadly infectious diseases, yet vaccine hesitancy threatens the emergence of vaccine-preventable diseases. The COVID-19 pandemic has caused the need for the largest mass vaccination campaign ever undertaken to date; however, African, Caribbean, and Black (ACB) populations have shown both a disproportionately high degree of negative impacts from the pandemic and the lowest willingness to become vaccinated. Low vaccination ...

 Open Access DOI:10.23937/2469-567X/1510093

Factors Associated with HIV/Tuberculosis Coinfection among People Living with HIV after Initiation of Antiretroviral Treatment in Lingwala Health Zone from 2021 To 2023

Jean Claude Mikobi Maleshila, Espérant Ntambue Malu, Fabrice Sewolo, Tacite Kpanya Mazoba and Jean Nyandwe Kyloka

Article Type: Original Research | First Published: 2024/03/08

Around 8% of incident cases of tuberculosis (TB) were reported among people living with HIV worldwide in 2022. Tuberculosis is the leading cause of death among people living with HIV. Africa accounts for the majority of co-infection episodes, with over 50% of cases in some parts of southern Africa. In the Democratic Republic of Congo (DRC), around 9% of persons living with HIV (PLHIV) develop TB and 11% of TB patients are infected with HIV. The DRC is one of the 30 countries in the world bearing...

 Open Access DOI:10.23937/2469-567X/1510092

Incidence and Predictors of Treatment Failure among Adult on First-Line Antiretroviral Therapy in Gullele Sub City, Addis Ababa, Ethiopia 2023: A Retrospective Study in Selected Public Health Facilities

Masresha Wondimgezahu Shawangardew, MPH and Tefera Tezera, PhD

Article Type: Research Article | First Published: 2023/12/31

Ethiopia is one of the countries in sub-Saharan Africa that was most affected by the HIV epidemic. In response to HIV/AIDS, Ethiopia implemented the antiretroviral therapy program in an effort to preserve lives. However, the occurrence of first line ART failure has had an impact on the outstanding success documented in lowering morbidity and mortality. This study was designed to identify the incidence and predictors of first-line ART failure in selected public health facilities at Gullele sub ci...

 Open Access DOI:10.23937/2469-567X/1510091

siRNA-Therapy for Hepatitis B Virus (HBV): A Novel Choice for HBV Treatment

Myra Sarfraz Iqbal

Article Type: Review Article | First Published: 2023/11/11

Hepatitis B virus (HBV) is a virus that may lead to chronic infection of the liver. Once infected, HBV may stay in the blood and liver for a lifetime. HBV is a non-retro virus that infects hepatocytes, with an underlying mechanism of converting its relaxed circular DNA (rcDNA), into closed circular DNA (cccDNA). The cccDNA then serves as a transcription template to transcribe viral RNAs utilizing the transcription factors meant for the host system's transcription....

 Open Access DOI:10.23937/2469-567X/1510084

Thrombotic Microangiopathies as Initial Presentation of HIV: Two Case Reports and Literature Review

Rawan AlAgha

Article Type: Case Report | First Published: March 09, 2023

Thrombotic microangiopathies have been recently a recognizable presentation of patients infected with Human Immunodeficiency Virus (HIV). Most of those who present similarly noted to have poor prognosis as majority have advanced HIV with low CD4 counts. It has postulated by some authors and researches that it should be recognized as an AIDS defining condition. Here we present two cases of adult males who presented with features of thrombotic microangiopathy and were diagnosed to have HIV for the...

Volume 10
Issue 1