Over the past five years clinicians from numerous countries have implicated human papillomavirus (HPV) immunizations as the cause of diverse systemic ailments, egregious injuries, and even death. Vaccine ingredients in Gardasil and Cervarix contain hidden organosiloxanes (organosilicones) and silica (silicon dioxide), all of which are capable of creating biochemical disturbances that are strikingly similar to the metabolic disruptions identified in both chronic fatigue syndrome and the recurrent public health debacle of silicone gel-filled breast implant toxicity.