Journal of

Rheumatic Diseases and TreatmentISSN: 2469-5726

Early Online

 Open Access DOI:10.23937/2469-5726/1510071

Urinary VCAM-1, KIM-1, and ET-1 as Biomarkers of Lupus Nephritis: Correlation with Immunological Parameters in Hospital USM

Siti Khadijah SM Nazri, BSc, Wan Syamimee W Ghazali, MD, MMed, Noor Suryani M Ashari, MD, MPath and Wan Zuraida WA Hamid, MD, MPath

Article Type: Research Article | First Published: May 15, 2019

So far, there is no conventional parameters that have been proven to possess the ability to predict the histology of systemic lupus erythematosus (SLE). A few autoimmune serology markers of SLE including anti-dsDNA antibodies, complement C3 and C4, and anti-nucleosome could be helpful clinically, but the correlation between those and lupus renal disease is still imperfect. Recently, the urinary vascular cell adhesion molecule-1 (VCAM-1), kidney injury molecule-1 (KIM-1) and endothelin-1 (ET-1) h...

Volume 5
Issue 2