Journal of

Clinical Gastroenterology and TreatmentISSN: 2469-584X

Current Issue

 Open Access DOI:10.23937/2469-584X/1510071

Risk Factors for Mucosal Ulceration in Gastric Gastrointestinal Stromal Tumors (GIST)

Eran Ariam, Anton Bermont, Yehuda Herskovitz, Shay Matalon, Bard Vyacheslav, Reut Yaakobi, Daana Baseem, Fadi Younis, Asia Zubkov, Efrat Broide, Benjamin Avidan, Steven F Moss and Haim Shirin

Article Type: Case Report | First Published: November 18, 2019

Gastrointestinal stromal tumors (GIST) are the most common subepithelial tumors in the gastrointestinal (GI) tract and they are usually located in the stomach. To date, only a few studies have investigated the risk factors for GIST ulceration and bleeding and there have been no prior publications focused on role of Helicobacter pylori in GIST ulceration. The aim of current study was to investigate the risk factors of mucosal ulceration in gastric GISTs. A retrospective study was conducted of 130...

 Open Access DOI:10.23937/2469-584X/1510070

Successful Treatment of Hepatitis C, Genotype 3, Treatment Failure (Sofosbuvir/Daclatasvir) with Sofosbuvir/Velpatasvir in Decompensated Cirrhosis Complicated by Renal Insufficiency

Marco Distefano, Lorenza Di Marco, Enzo Scifo, Salvatore Gruttadauria, Gaetano Scifo and Vito Di Marco

Article Type: Case Report | First Published: September 30, 2019

Clinical trials and real word data have proven that chronic hepatitis C (HCV) can be eradicated (sustained virological response SVR or ‘cure’) in the majority of patients by direct - acting antivirals (DAAs) . There are, however, groups of patients in whom HCV treatment outcomes with direct acting antivirals (DAAs) are suboptimal (genotype (GT) 3 patients, decompensated cirrhosis, renal failure) or have not been studied in large cohorts (patients with relapse to a previous DAAs treatment (fa...

 Open Access DOI:10.23937/2469-584X/1510069

Cannabinoid Hyperemesis Syndrome in Pregnancy: A Case Report and Treatment Overview

Tram Anh H Nguyen and Melissa C Palmer

Article Type: Case Report | First Published: September 26, 2019

Nguyen TAH, Palmer MC (2019) Cannabinoid Hyperemesis Syndrome in Pregnancy: A Case Report and Treatment Overview. J Clin Gastroenterol Treat 5:069. doi.org/10.23937/2469- 584X/1510069...

 Open Access DOI:10.23937/2469-584X/1510068

High Anti-Acid Omeprazole Lightweight Capsule for Gastro-Enteric System Acid-Related Disorders Treatment

Longjian Geng, Lidong Han, Lulu Huang, Ziheng Wu, Zhenghong Wu and Xiaole Qi

Article Type: Research Article | First Published: September 26, 2019

Utilization of diverse anti-acid materials is necessary for the preparation of compound omeprazole capsules. However, to gain the satisfied anti-acid effect, use of large amount of anti-acids is always difficult to swallow. This study aimed to develop a lightweight compound omeprazole capsule which could achieve immediately drug releasing with high anti-acid ability in stomach. In this study, we successfully prepared OMZ-CD, which were characterized and compared with micronized OMZ. An improved ...

Volume 5
Issue 2