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Clinical Gastroenterology and TreatmentISSN: 2469-584X

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 Open Access DOI:10.23937/2469-584X/1510075

Covid-19: Gastroenterology Perspectives

Natassia Vianna Bocchese, Noele Gurgel Dávila, Maria Beatriz Maia Rodrigues, Rebecca Renata Lapenda do Monte, Renata Carneiro Melo, Amália Cinthia Meneses Rêgo and Irami Araújo- Filho

Article Type: Review Article | First Published: June 29, 2020

The clinical syndrome caused by SARS-CoV-2 was called COVID-19 and became a pandemic from March 2020. Fever, dry cough, and dyspnoea are the predominant clinical manifestations of the disease. However, symptoms such as diarrhea, nausea, vomiting, and abdominal discomfort can also be found in infected patients. Despite the increased prevalence since the second phase of the recent epidemic in China, scientific evidence on the gastrointestinal manifestations of COVID-19 has received little attentio...

 Open Access DOI:10.23937/2469-584X/1510074

COVID-19 and Liver Injury: Hepatology Perspectives

Natassia Vianna Bocchese, Noele Gurgel Dávila, Maria Beatriz Maia Rodrigues, Irami Araújo- Neto, Mariana de Oliveira Costa, Diniz de Meiroz Grillo Barbalho, Amália Cinthia Meneses Rêgo and Irami Araújo-Filho

Article Type: Review Article | First Published: June 27, 2020

SARS-CoV-2, a severe acute respiratory syndrome caused by Coronavirus 2, discovered in 2019 in China, is responsible for the current pandemic declared by the WHO since March 2020. The clinical syndrome caused by Covid-19 has a broad spectrum of severity. The most common clinical manifestations are fever, dry cough, dyspnea, fatigue, and anosmia. The virus binds to receptors for angiotensin-converting enzyme 2 (ECA2) and serine protease TMPRSS2 for protein S initiation, which are expressed not on...

 Open Access DOI:10.23937/2469-584X/1510071

Risk Factors for Mucosal Ulceration in Gastric Gastrointestinal Stromal Tumors (GIST)

Eran Ariam, Anton Bermont, Yehuda Herskovitz, Shay Matalon, Bard Vyacheslav, Reut Yaakobi, Daana Baseem, Fadi Younis, Asia Zubkov, Efrat Broide, Benjamin Avidan, Steven F Moss and Haim Shirin

Article Type: Case Report | First Published: November 18, 2019

Gastrointestinal stromal tumors (GIST) are the most common subepithelial tumors in the gastrointestinal (GI) tract and they are usually located in the stomach. To date, only a few studies have investigated the risk factors for GIST ulceration and bleeding and there have been no prior publications focused on role of Helicobacter pylori in GIST ulceration. The aim of current study was to investigate the risk factors of mucosal ulceration in gastric GISTs. A retrospective study was conducted of 130...

 Open Access DOI:10.23937/2469-584X/1510070

Successful Treatment of Hepatitis C, Genotype 3, Treatment Failure (Sofosbuvir/Daclatasvir) with Sofosbuvir/Velpatasvir in Decompensated Cirrhosis Complicated by Renal Insufficiency

Marco Distefano, Lorenza Di Marco, Enzo Scifo, Salvatore Gruttadauria, Gaetano Scifo and Vito Di Marco

Article Type: Case Report | First Published: September 30, 2019

Clinical trials and real word data have proven that chronic hepatitis C (HCV) can be eradicated (sustained virological response SVR or ‘cure’) in the majority of patients by direct - acting antivirals (DAAs) . There are, however, groups of patients in whom HCV treatment outcomes with direct acting antivirals (DAAs) are suboptimal (genotype (GT) 3 patients, decompensated cirrhosis, renal failure) or have not been studied in large cohorts (patients with relapse to a previous DAAs treatment (fa...

 Open Access DOI:10.23937/2469-584X/1510062

Knowledge and Attitudes of Internal Medicine Trainees' Co-Prescribing Patterns of Gastroprotective Agents in Patients Taking Long-Term Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Nikki Duong, Alice Lee and James H Lewis

Article Type: Research Article | First Published: July 13, 2018

The side effect profile of NSAIDs is well-established. For prevention of NSAID-related ulcers, the evidence suggests that misoprostol and PPIs (proton pump inhibitors) are superior to H2RAs (histamine-2-receptor-antagonists). Current guidelines recommend use of the lowest possible NSAID dose, as well as consideration of the patients' gastrointestinal and cardiovascular risk profile....

Volume 4
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