Covid-19: Gastroenterology Perspectives
Natassia Vianna Bocchese, Noele Gurgel Dávila, Maria Beatriz Maia Rodrigues, Rebecca Renata Lapenda do Monte, Renata Carneiro Melo, Amália Cinthia Meneses Rêgo and Irami Araújo- Filho
Article Type: Review Article | First Published: June 29, 2020
The clinical syndrome caused by SARS-CoV-2 was called COVID-19 and became a pandemic from March 2020. Fever, dry cough, and dyspnoea are the predominant clinical manifestations of the disease. However, symptoms such as diarrhea, nausea, vomiting, and abdominal discomfort can also be found in infected patients. Despite the increased prevalence since the second phase of the recent epidemic in China, scientific evidence on the gastrointestinal manifestations of COVID-19 has received little attentio...
COVID-19 and Liver Injury: Hepatology Perspectives
Natassia Vianna Bocchese, Noele Gurgel Dávila, Maria Beatriz Maia Rodrigues, Irami Araújo- Neto, Mariana de Oliveira Costa, Diniz de Meiroz Grillo Barbalho, Amália Cinthia Meneses Rêgo and Irami Araújo-Filho
Article Type: Review Article | First Published: June 27, 2020
SARS-CoV-2, a severe acute respiratory syndrome caused by Coronavirus 2, discovered in 2019 in China, is responsible for the current pandemic declared by the WHO since March 2020. The clinical syndrome caused by Covid-19 has a broad spectrum of severity. The most common clinical manifestations are fever, dry cough, dyspnea, fatigue, and anosmia. The virus binds to receptors for angiotensin-converting enzyme 2 (ECA2) and serine protease TMPRSS2 for protein S initiation, which are expressed not on...
Risk Factors for Mucosal Ulceration in Gastric Gastrointestinal Stromal Tumors (GIST)
Eran Ariam, Anton Bermont, Yehuda Herskovitz, Shay Matalon, Bard Vyacheslav, Reut Yaakobi, Daana Baseem, Fadi Younis, Asia Zubkov, Efrat Broide, Benjamin Avidan, Steven F Moss and Haim Shirin
Article Type: Case Report | First Published: November 18, 2019
Gastrointestinal stromal tumors (GIST) are the most common subepithelial tumors in the gastrointestinal (GI) tract and they are usually located in the stomach. To date, only a few studies have investigated the risk factors for GIST ulceration and bleeding and there have been no prior publications focused on role of Helicobacter pylori in GIST ulceration. The aim of current study was to investigate the risk factors of mucosal ulceration in gastric GISTs. A retrospective study was conducted of 130...
Successful Treatment of Hepatitis C, Genotype 3, Treatment Failure (Sofosbuvir/Daclatasvir) with Sofosbuvir/Velpatasvir in Decompensated Cirrhosis Complicated by Renal Insufficiency
Marco Distefano, Lorenza Di Marco, Enzo Scifo, Salvatore Gruttadauria, Gaetano Scifo and Vito Di Marco
Article Type: Case Report | First Published: September 30, 2019
Clinical trials and real word data have proven that chronic hepatitis C (HCV) can be eradicated (sustained virological response SVR or ‘cure’) in the majority of patients by direct - acting antivirals (DAAs) . There are, however, groups of patients in whom HCV treatment outcomes with direct acting antivirals (DAAs) are suboptimal (genotype (GT) 3 patients, decompensated cirrhosis, renal failure) or have not been studied in large cohorts (patients with relapse to a previous DAAs treatment (fa...